HsaINT0003368 @ hg19
Intron Retention
Gene
ENSG00000123612 | ACVR1C
Description
activin A receptor, type IC [Source:HGNC Symbol;Acc:18123]
Coordinates
chr2:158406674-158412844:-
Coord C1 exon
chr2:158412605-158412844
Coord A exon
chr2:158406905-158412604
Coord C2 exon
chr2:158406674-158406904
Length
5700 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGT
5' ss Score
8.14
3' ss Seq
TCCATCTTTTCTTTGGTTAGGTC
3' ss Score
8.66
Exon sequences
Seq C1 exon
CATCACCAAATGCCCCAAAACTTGGACCCATGGAGCTGGCCATCATTATTACTGTGCCTGTTTGCCTCCTGTCCATAGCTGCGATGCTGACAGTATGGGCATGCCAGGGTCGACAGTGCTCCTACAGGAAGAAAAAGAGACCAAATGTGGAGGAACCACTCTCTGAGTGCAATCTGGTAAATGCTGGAAAAACTCTGAAAGATCTGATTTATGATGTGACCGCCTCTGGATCTGGCTCTG
Seq A exon
GTATGTTACCATTGTCCATTTTTTTAAAATAAGAAAACACTTTTATTTAAAAGTAAATAAAAACTTTTTAACAAAAAGGGCCCAAATATTATGAATTCCGTCTTGAAAGGATACATGGTGAGCTCTGGTATAGGAACTCCTTTTAGTACCTGAGGAAGAGAAAAACCATCGTGGCCTATAGAATTAAGTCTTCTCAGTTGCTTTTTGTAGCTTTAGGTGTTCAGATTCTTACATTCACTTTCCTTCAGAATTTATTTCTGAAGCAAAAAAGCAATTTCCCTTCTCTCCTCCCTGCTTCCCCCCATTATGGTTACTAACAATCACTGTTGCTTTGTTGATAATGTTTTATGGACACAAAAGAGTTAGGGTTGTGGTATTTAAGGTGTTGAGTTCTGAGGGAAAGATGTTGGTTATACAAAGTAGTGTTCTTTGAGCTCTTTTGCTTGTGGGTATGAGGATTTTCAGAATCTATAGACACCCCCTGAGATGTGTGTGAAGCTAACAGGGAACTCACCTAAAATTAAATCAAGAATATGTTCTTAAAGCAAAGAAACAGAAGATTAAAGAGAGCAGTGCAGCATTCCTGTGCTGGCTTTTGCTGGCTGTGGTTACATACATGACTGTCTTCCTCTTTAATGGAACTCCAGAACCCCAGGTAAAGCGTTCAAAGTACCGGCCGGGCGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCATGAGGTCAGGAGATCGAGACCATCCTGGCTAACAAGGTGAAACCCCGTCTCTACTAAAAAATACAAAAAATTAGCCGGGCGCGGTGGCGGGCGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATGGCGTGAACCCGGGAAGCGGAGCTTGCAGTGAGCCGAGATTGCGCCACTGCAGTCCGCAGTCCGGCCTGGGTGACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAAAAAAAAAAGCGTTCAAAGTACCAGGCTGTATTATAGCCTAAATGAGCCTTTCTCACAACACAAAGCATTTGAAGGTTTTTTATTTTTATTTTTATTTTTTATTTTTTTATCTTTTGGCAGGAGGTTGGCGGAGTGGGGGGACAGTTTTCCCCAGAATAACAAACTCCCTAAAATGGTAGGGGATTCCATATATATATATATCCAGAAATCCTGCCAGCTCATGGTTTATGAAAATACGAACAAGAGTAACCCTAGGTGAGCCACTTCAGAGGCCCCTGCATCTCTTCTTGTTTTGGAAGGATCATTAAGATAGTAGCCCAACATTCTGAAGAACTCCCTTGCCAATGGCTTTCGGGAAAATCCAGGCAGTAACAATTAACAGAGGTAGGCAACAGAGGGCTGATAACATCTCTATGTGCATCCATATTTAGCATGAAGCTGCTTTGGATTCATCAGAAAAGAAAAGCATAATCAAACCCAGATAGTTCGCTCCTTCTGGGGCAAAATCACCTGGCCTCCCACTGACGAAGACTAAATGTTTACACCATCACTGTACACATTAGGTAGCATCTTTCAAAGGAAGAATACTGGTAAGAAAACCCCCAAACTGCAAAGTTTTAAAAACCAGAATTTAAATTAAAATAAATTATTGGCTAGACGACTGGCACCTTCCTTCCTTCCTTCCTTTGTCTCCTTCCTTCCTTCATCTCCTTCCTTCCTTCCTTCCCTCCCTCCCTCCCTTCTTTCTTTCTTTCTCTTTCTTTCTTTCTCTCTTTCTCTTTCTTTTTCTTTTTCTTTTCCTTTCTTTCTTTCTCTCTCTCTCTCTCTTCCTTCCTTCCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTCTCTTCTTTATTTTTTTTTTTTCCAGATTCTCACCCTGTTACCTAGGCTGGAGTGCAGTGGTGCTATCTTGGCTCACTGCAACCTCTCCCTCCTGGATTCAAGTGATTCTCCTACCTGAGCCTCCTAAGTAGCTAGAATTACAGGTGTGCCCCACTACACCTGGCTAATTTTTGCATTTTTAGCAGAGATGGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGAACTCAAGTGATCTGCCTGCCTTGGCCACCCAAAGTGCTGGGATTACAGGTGTGAGCCACTGCACCTGGCCACATTTTTCTTTAAAATTAAAACTTGTTGATATTCAATACTGTTTCCTTCTTTGACTCTGACACTTTGAGGCCCACTGTGCCCTGATTTCTTGAATATTGACAACATTCTAGGCACAGAGACCTCTGATTTATGGCAAGTTTCTTGAAACCTTATATAATTTCTTTATAAGGTTCAAGAGGTTAAATAACTCTCTGCTTAATCCCCATCCCCAAAACCATTTTAATTATCTGAAGATGTTAGATAAAAACGTGCATTTTGGAACTATTCCTTAAATACATTTAAGATAACCAAAGATTTTCCTTTCAAATGAAAGCAATTCAGATTTTAATGCTAGAGACTGGGATTTAGTTTGAGAAAGTAGTCATGGGCTAGGGCAGAAATCAAAAATTAATGTTACATTTTCTGGTGTTTTTTGCATGTTTAAACCTAAATCTGGAATTACTGATTCTGGACTCTCTCGTTTTCAGATTATTCTAAGATCTCTCATTTAAAAAAAAAAAAAGTAGTAAATGTACCCAAGCATGGATGATTTCTTTAAATACCAATCTGAAAGAGCTTTAGGCATTTTTCCCCCAAAGCCAGTTGCATACGTTTGGCAGTGACCAGTGGCTGAAAGTAACAGAAGGCCTCCCTGCCTTTGATAATCAGAGAATGGGTGTATCCGCAGTGAGGCTTCAGTCATAAAAGCTCACCTGTAGGGAGGGGATTGGAGGAGGGGGGAGTCTGATTCCCTCTGCTTTTCTTAATTGGCCAGTAACTTTAAATGTGAGACAGTTTGTCAGATGCTGAGGAACAAAAACTGTGAAGCGTATTCTTGACCTGGTCAGGGACAAATTTCAAAGACATGCATAATGCCTGCAAGAGGGGAAAATGGACTGATGAGAAATGATGGTGTCTCAGATGGCTTCCAAGAAACTGGGTAGGTTGCTGCTTTTCTCTTGTGGTGTAACAATTCTGACTGATGGTGACATTATTGAAAGCTAACCTTCTACACCCCCTGGTTAAAAGATTGAAATGAACCTACAGGGAGAAGCAAAAATCCATGTATCTTCAAATGAAATGTCTAGGTGCATAACAGAAGAATTAGATTCATTTTGGTGGTTGCTTTGAAAGATACCAAAGCAAATTTTATTGAGTTTTAATGTCTCAATTTAATTGCTGTCTCGAGTACTTTATATATTGTTGTCTTACTTTGTTCCTGATCTGCACCACTGATTATGTACTTGATTAATTTGCAGTTTGAAAGCATAAGCTTATCTAGCTCTCCATCCATTTGTTGTGTTTTGGGTAGTGCTGGTTGTTGGTAGTGATGTTTCTGTGAGTGTGCATGTATGTATGTGGATAAGACTATAGGTTAGCAGGAGGAAGGGAGAGACTGAGATTGAGATTTGGCCTAATAATTGTTAGCATAACTTTTAGTGTGTGGTCAAGTAGTAAAATTGATTGTTGCCTGCAAAAACAGTCCAGGCTGGTTGCAGTGGCTCACGCCTGTAATCCCAGTACTTTGGGAGGCCGAGGCAGGTGGATCACTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCTCTTCTCTACTAAAAATACAAAAATTAGCTGGGTATGGTGGTGCACACCTGTAGTCCCAGCTACTCAAGAGGCTGATGTGGGAGAATCGCTTGAACCTGGGAGGTGGAGATAGTAGTGAGCTGAGATCATGCCACTGCACTCCAGCCTGACAGAGCAAGACTCCATCTCAAAAAACAAACAAACAAACAAACAAAACAAACCAACAAACAAAAACAGTCTTATAGTTTGCTTCTAGACAGGAACAGTTTGCACTGAAGATCAGTGTTTTAGTTCTAGGTCTGCCTCTCACTAGCAGCATAATCCTGGGAAAGACTTTGATTATCGAGGGGCCTCAGTTTTGCCATCTCTAAAATGATAGGGTTGAACCAGATAATTTCAAAAGAACTTTCTTCCTGTAGGGTTTTGTGACTAATTGTTGAGATCCGTAACAGCAGATTTGTAGTCTGTGCTTATTTAGCCTGTGCTTATATGTCCATATGAGAACATGTGAATGAACAGTGACTAGTTTTAGGTGCAGGGACCAAAGCCCCTGCAAGACAGGGTCATTGCTATGAGGGTTCCCTAGCTGTCTGAGTACAAAAACAGTAACTAAATGTGACTTTTCAGAATAAATGTAGACTGTAACCTCTTTAACTATTTTTCCTTTGATTTTAAGAGCAATAAATATCAATTGTGGAAATTAAGAAAATGTGGAAAATTAGAAAGAAGACTATCATAACTCACCCCGGTTTCACCAAGAGAAATAACCATCATAACATTTAGCATGCTTCCTTTTGAGTCTTATTTTCTGTGCATATTTTGAATAGCTAGATACACTTATATTTATAAGAATAAAATGTACTATGCTGTTTTTATTTAATATTATAGCAAAAGTATTTTTTCATGTTATTAGATACTTCTTCATAAGCATCATCATTATTATTGGCTCTGAGTAAGCCATCCTAAGATTAACATAATGTTAACCATTATTGAACATGTAATATGCCAGATACTGTGCTAGGTGCTGAACATGCTTATTAATTCTCATATCATCTCTGCGAGATGCGTAATATTGATTATCCCCAGTTTTTCAGATGAAGAAGCTGAAGCGCAGACAGGTGAAATAACTTGTGCATGATTACCAGGTGGCAGAGCTGAAATCTGAATCCGCCTGTGCTCTTAATCTCTGCACTTTATTTCACAATTATTCCATTACCTGACACTTTTACTTATTTTATTCCTATAAATAATAATAAGATATTAAACATCTTGACATAAATTTTTCTACATTTTGCATTAAGTATTTGCGACAGAATTCTAGAGGTGGAGTTAGTAGTTCAAAGAATATAAGCGTTATACATACATTCAGGATATATTTTCTTTGAAAATTTTTTTTTGTTCTGCAGAAAATATTCATTTGATATCTTATTTGACTATATCTTGCTTTTAGTGTAATATCATTATCTCACATGATCATTGTATTTGATTCTTCACTTTCCAATTTGAGCTTGGTTTTTGAAAAAATTCACAAATAATTATTTTGCTCTTCCAGTTGTACCAGGAACCATACATTTTATTTTAGAGGCTAACACTTCTTTTTTTTTTTTTTGCTTTTACTCTTGTGTACTTAGTAACCTGACTGGCTTTGATGGGCAAATGAAGGAGATTTGCAGCAATTCTTGGAAATCAGATATCTGTAGCAGCAGGCTATGTTCAAAAAATTTTTACTTGTGAATACGACAAGACAAATTCATATTCATAATTTGAAGTATTTTTTTCAGCATGCTTTGACATTAAATAAGTTTGCTATAATGGTACTTATTCCTTCAAAATAGATAAAATTATTAAAGCATTTAAATGTTTGCTTTTTTAAAATCTGAAAACAGTGATTATTGAGAGTTCTTTTCTGACATTTGTGTTTAATTATCAATTCCATCTTTTCTTTGGTTAG
Seq C2 exon
GTCTACCTCTGTTGGTTCAAAGGACAATTGCAAGGACGATTGTGCTTCAGGAAATAGTAGGAAAAGGTAGATTTGGTGAGGTGTGGCATGGAAGATGGTGTGGGGAAGATGTGGCTGTGAAAATATTCTCCTCCAGAGATGAAAGATCTTGGTTTCGTGAGGCAGAAATTTACCAGACGGTCATGCTGCGACATGAAAACATCCTTGGTTTCATTGCTGCTGACAACAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123612-ACVR1C:NM_145259:3
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF085157=TGF_beta_GS=PU(58.6=21.0)
A:
NA
C2:
PF085157=TGF_beta_GS=PD(37.9=14.1),PF0006920=Pkinase=PU(22.2=82.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)