HsaINT0004365 @ hg38
Intron Retention
Gene
ENSG00000185761 | ADAMTSL5
Description
ADAMTS like 5 [Source:HGNC Symbol;Acc:HGNC:27912]
Coordinates
chr19:1506590-1506928:-
Coord C1 exon
chr19:1506739-1506928
Coord A exon
chr19:1506662-1506738
Coord C2 exon
chr19:1506590-1506661
Length
77 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
CAGCACCGCCCATCCCACAGACC
3' ss Score
5.89
Exon sequences
Seq C1 exon
GTCCTCCTGCAGGAGCCCAACCCTGGCATCGAGTTTGAGTTCTGGCTCCCTCGGGAGCGCTACAGCCCCTTCCAGGCTCGTGTGCAGGCCCTGGGCTGGCCCCTGAGGCAGCCTCAGCCCCGGGGGGTGGAGCCTCAGCCCCCCGCAGCCCCTGCTGTCACCCCTGCACAGACCCCAACGCTGGCCCCAG
Seq A exon
GTGAGGTGGGGACAGCCAGGGTGGGGGATGAGTGGGGACTGAGGCCTGTGCCCCTCACAGCACCGCCCATCCCACAG
Seq C2 exon
ACCCCTGCCCACCCTGCCCTGACACCCGCGGCCGCGCCCACCGACTACTCCACTATTGCGGCAGTGACTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000185761:ENST00000330475:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.529 A=NA C2=0.360
Domain overlap (PFAM):
C1:
PF059869=ADAM_spacer1=PD(14.5=25.0)
A:
NA
C2:
PF0175916=NTR=PU(7.7=32.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCCAGGCTCGTGTGCAG
R:
ATAGTGGAGTAGTCGGTGGGC
Band lengths:
178-255
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development