HsaINT0017053 @ hg19
Intron Retention
Gene
ENSG00000137936 | BCAR3
Description
breast cancer anti-estrogen resistance 3 [Source:HGNC Symbol;Acc:973]
Coordinates
chr1:94033297-94037398:-
Coord C1 exon
chr1:94037227-94037398
Coord A exon
chr1:94033409-94037226
Coord C2 exon
chr1:94033297-94033408
Length
3818 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
3' ss Seq
AAACACCACCTTTCTTCCAGATC
3' ss Score
7.25
Exon sequences
Seq C1 exon
ACACAACACAATGGCCATCGGCATTGCAGTGGACATTCTGGGATGCACGGGCACTTTGGAGGACCGAGCGGCCACTCTGAGTAAGATCATCCAGGTGGCGGTGGAACTGAAGGATTCCATGGGGGACCTCTATTCCTTCTCAGCTCTCATGAAAGCCCTGGAAATGCCACAG
Seq A exon
GTAAATTTCCAATTACTTTATGTGTACTTAATGTTCTGTAAAGAGATCTGCATGCCATGTTTGGCAAATCAGACTATTTTAGTCAATCTCAAAAGTAAATTGAATCTTAGTGAAAGCTGCTTCATTTAGGGGACAGTGTCCTAAGTATTTGGGGTCTACTTTTTTTTTTCTTTTTTGAGACAGAATCTCACTCTGCCACCTAGGCTAGCAGTGGCACAATCTCAGCTCACTGCAACCTCCACCTCCCAGGCTTAAGTGATTCTCATGCCTCAGCCTCAAGTAGCTGGGACTATAGGCAGGCACCACCACACCCAGCTAATTTTTGTATTTTTAGTAGGGACAGGGTTTCACCAGGTTGGCCTGGAACTCCTGACTTCACATGATCTGCCCGCCTCAGCCTCCCGAAGTGCTGGAATTACAGGCATGAGCCACTGTACCTGGACTGGGGTCTATTTTTTTTTTTTTTTAAACGAAGTCTCGCTCTGTTGTCCAGGCTGCAGTACAATGGTGTGATCTTGGCTCATTGCAACCTCTGTCTCCTGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATAACAGGCGTGGGCCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTTGCCATGTTGGCCAGGCTGATCTCGAACTCCTGACCTCAGGTGATCTGCCCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAAGCACCACGCCCAGCCTCTGGGGTCTATTTTTTAAGGCAGTAAATATTTGCTGACAGTCCATGCTTTCTCTTTGATGTACAGTAGCAAGTGTCATCCTCATGAACAGTAGTGATTCAAGGAGAACCAATTAGGATGAGACATCTGGCTAAAGTGTGTTGTATAAGAAGGAGACTGCCTCCATCTGGGTCACCAGGTGTGGGCAGTCTAGGATAATCACTGGGAAATGAGACATTTGCAGAGCTTCTATCAGAATCCTTAGAATAGTTTATCTCAGGTCACCTAAAACAGACTGTCCTATTAAAAAGTTCGGATTCCTGGTCCATCTGCCATAGAACTCCCTAATTACCGTTTCTGAAACTGGGCATTTGAATTTATCTGCTGTGCCAGGGATTTTTTAGGATGAGTGTCAAACCTGAATATCTGTATCTGAAGTCAAGCAGGCCTCATAGAGGAAAGTCAGGCTGCCATCTTTATTGCTGAGGATCAGCACTCCCACTTCTGTTCTCCCAAGCCCTGGATGCTTGGAGGACTTGAGTATGAGTTTACAGTCCAGCCAGCAAAACTTTCTAGTAACACCAAAACCGCTGGTCACTCGGCTTGGCTGTTTCATAGCCACAGGTTAGCTCTGAAATCCTGCCAGGTACTCACTGAAATTCCATCATTGCCACTGAAAAACAGCCACAATCACATGTCCCGCAAGTCAGATCATGGCAGGAATAGAATTTACTTGCATTAAAGCAAGGTCACCTTAAAAATAAAAAGTTGAAAACTTAGTGCCTTCATCGGGAATTTGTGGGGGGTCAATTCTAATTATATTTCAGAAGCTTTCAGAATTCTTCAGGTAGACTGGTATTTTGTAGGATTGGTATTTGAAATAAGCAGCCCATAAGTTCTGCCAGATTTTCATGATATACTGATTTCTACTATAACGGGTTATCATTTTTTCATTCAGGTATTTTAATGTGCATTATGTTTATTTCCTGTCACCTAAAACTGCCTAGAATTTTGACAGCAGAGCCAACAGGCCAGGCTGTGGGTAAAGCCTTCCAGCCCAGAGCTTCCCCTGAGACTGGTAAAGGAGATGTTTTGTGGGATCACATGGTTGCCATCCATGACATCAAACTCAGCAGTTAGGGACTTGTCCCCAACCACATTACCATGCTTTGTAGGCGGCTCCCTGCCTTCTAACAGTGTCAGCCTTTCCCTTCTGGAGCACATCAGCAGTGACAGGACACAGTCCTCCAGAGCATACAGTGGCCTAGGAGGAAGTGGCATACCCAGAGAAAGCCCAAAAGGAGGGTCACATTACTTTGCGTGTCACCATCCAACCCAGCCCTTACACTATAGCCACATCTGCCACCTTCTCTTCTCAGCTTCTAGTATCAAGAGAATATGTCCAGGAGATGGGCCTAGCCCAGACCCAGAGGCTTCTTTCAGAAAGGCAATGCCTCAGGGAGTGGGTGTAGGGAGCAGGGGTCTACAGAAGGAAGGGCAGCATGGTGGGCAGCAGGAGGAAGGCGGCCACAGCCTTTTCTTCACAGCACGTCTGCTGGTGCTGAGCCTACTCACCTTCCTTTTGGATACAGGAGCTCTTCAAGGCCAAGTAAATGAATCTCAGCTCTACCACATACCAGCTGGGAAGCCTTGGGCAGTTACCTAATCTCTTCTGTTTTCTCATCTGTAAAAGCCAAAATACCTGTCTTAAAGGGCATTGTGAAGATTAAATGAAATTCTTCAAATATTTGACACAAACTTGGCTCTTATTCCCCAAATACTAATGCCCTTCCTTGTTTCATGTAGAAAACTTAACATAGCCTTGCCGGTTTTAGGGTATGAGTTGGGGACCATTTATCTTAGGACAGTCAGAGTCAGTGGTGTATGCTGCTGCTGACTAAATTGTTCCAAAAGAAAATTGAGGCCCTGAGTTACCTGCAGAAGAAAAGAAATGAGTAGCAGGCATGGTGTCTCATGTTTGTTGTCCCAGCTACTCAGAAGGCTGAGGTGGGAAGATCACTGAGCCTGGGAGGTTGAGGCTACAGTGAGCTGTGATCGCACCACTGCACCCCAGCCTGGGCAACAGAGTGAGACCCCATCTCAAAGAAGAAAAGTCATAAAACTCTTTAAGAGACGAGTTAAACTATAGCTATCCATACAGTGGACTATTATGCAGAAATTTAACAAAATAAGGCTGTTCTATATGTACTTATACTGAATGCTTTTGAGGCAAGGAATGGGTGTGGTTTATGTAGTATATAATATGCATGTATTTATTTTTAAAAGGGGTGTGCGTATAGACAGGAATTTTGGGGAGGTCAATTCCAGTTTTATTTCAAGAGCTTTCAAAATTCTTCAGGTACACTGGAATTTTCTAGGATCAGTATTTAAAATAAGCAACATCAGTTCTGCCGTATTTTCATGATAATGCTGATTTCTATTATAACAAGAGTGTAATTTTTCATTCAGGTGTTTTACTTTGCATCATGTTTATTTCCTCTCATCCAATACTGCCTTGAATTTTGACAGTGGACTGGCCAGCAGGCCAGGCTGTATGTGAAACACACACGCACAAGCAGTTGAAGAGAGTTGCCATCTCTGGGATGCGCTAACAGCAATGCAGATGGGGCGGATGGGGGATTATTTTTTCTTTCTACCCTGCTTTCAGACACTTTGACATTTTTACCATGTGTATCTATCACCTGTTCCAAAATTTAAGCAAAAGGGTAATTTTATTTTATTTATTTTTTTTTTTTTGAGACAGGGTCTCACTCTGTCAACCAGGCTGGAGTGCAGTGGCATGATCTTGGCTCATTGCAACCTCCGCCTCCCAGGTTCAAGCAATTCTCCCGCCTCAACCTCCCGAGTAGCTGGGATTACAGGCACACGCCACCACGCCTGGCTAATTTTTGTATTTGAGTAGAGACAGGGTTTCACCATACTGGCCAGACTGGTCTTGAACTCCTGACCTCAAGTGATCCACCCGCCTCAGCCTCCCAAAGTGCTGGCATTACAGGCGTGAGCTACCACGCCCAGCCACTAAAAGGTAATTTTAAAAAGAACCTTTTCCAAAACACCACCTTTCTTCCAG
Seq C2 exon
ATCACAAGGTTAGAAAAGACGTGGACTGCTCTGCGGCACCAGTACACCCAAACTGCCATTCTCTATGAGAAACAGCTGAAGCCCTTCAGCAAACTCCTGCATGAAGGCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137936-BCAR3:NM_003567:9
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(29.1=100)
A:
NA
C2:
PF0061714=RasGEF=FE(18.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)