HsaINT0025095 @ hg19
Intron Retention
Gene
ENSG00000176919 | C8G
Description
complement component 8, gamma polypeptide [Source:HGNC Symbol;Acc:1354]
Coordinates
chr9:139839698-139840222:+
Coord C1 exon
chr9:139839698-139839910
Coord A exon
chr9:139839911-139840085
Coord C2 exon
chr9:139840086-139840222
Length
175 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGAA
5' ss Score
6.68
3' ss Seq
CTCCCATGGTCTGCCCCCAGTTT
3' ss Score
8.47
Exon sequences
Seq C1 exon
AGAGTAGACTCTGTCCTGGGACTTGGTGGTGCTACCCTTGGCCTCCCACAGTCCTGCCACCCTGCTGCCGCCACCATGCTGCCCCCTGGGACTGCGACCCTCTTGACTCTGCTCCTGGCAGCTGGCTCGCTGGGCCAGAAGCCTCAGAGGCCACGCCGGCCCGCATCCCCCATCAGCACCATCCAGCCCAAGGCCAATTTTGATGCTCAGCAG
Seq A exon
GTAGAAGTTGGGGGGGGTAGAGGGAGGCAGGTAGAAGTTGTGGGAGGGGTAGAGGGAGACAGGTAGAAGTTGTTGCGGGGGAGAGGGAAGCAGGTGAAGTTGTGGGGGGTGTAGAGGGAAGCAGGTGAGGGGCCCTCCCACAGTGCCCTCGAGTTCTCCCATGGTCTGCCCCCAG
Seq C2 exon
TTTGCAGGGACCTGGCTCCTTGTGGCTGTGGGCTCCGCTTGCCGTTTCCTGCAGGAGCAGGGCCACCGGGCCGAGGCCACCACACTGCATGTGGCTCCCCAGGGCACAGCCATGGCTGTCAGTACCTTCCGAAAGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000176919-C8G:NM_000606:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.326 A=NA C2=0.065
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0006118=Lipocalin=PU(31.7=95.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACCCTCTTGACTCTGCTCCT
R:
GAAGGTACTGACAGCCATGGC
Band lengths:
247-422
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)