HsaINT0027386 @ hg19
Intron Retention
Gene
ENSG00000182472 | CAPN12
Description
calpain 12 [Source:HGNC Symbol;Acc:13249]
Coordinates
chr19:39230691-39232550:-
Coord C1 exon
chr19:39232417-39232550
Coord A exon
chr19:39230860-39232416
Coord C2 exon
chr19:39230691-39230859
Length
1557 bp
Sequences
Splice sites
5' ss Seq
CAAGTGAGG
5' ss Score
5.85
3' ss Seq
CCCCAGATCTGCCCCCACAGGCT
3' ss Score
6.77
Exon sequences
Seq C1 exon
CTCTGGCAGTTTGGCCGCTGGATGGACGTCGTGGTGGATGACAGGCTGCCCGTGCGTGAGGGGAAGCTGATGTTCGTGCGCTCGGAACAGCGGAATGAGTTCTGGGCCCCACTCCTGGAGAAGGCCTACGCCAA
Seq A exon
GTGAGGACCCCAGTTCCAACCAGCTGCAGCCCTAAGTCCCCACAGCAGGCATCAAGCCACAGGGGGACCCAGAGTCCCCCAAGCTCTGCAATCCTCCAAACACCCCACCAAGAATCCCAAACCAAGTGACAACCGCCAGAACCCTCATATCACAACATCACCTGAGCAACTTCATGTTTTTTTTTTTTTTCTTTTTTTTTGAGACGGAGTCTCACTCACTCTGTCGCCCAGGCTGGAGTGCAGTAGCGCGATCTTGGCTCACTGCAACCTCTGCCTCCCAGGTTCCAGCGATTCTCCTGTCTCAGCCTCCCGACTAGCTGGGATTACAGGAGCGCACCACCATGCCTGGCTAATTTTTATATTTTTAGTAGAGATGGGGTTTCACCATGTTGGTCAGGCTGGTCTCCAACTCCTGATCTCAGGTGATCCACCTTCCTTGGCCTCCCAAAGTACTGGGATTACAGGTGTGAGCCACTGTGCTCAGCTGTACCTTCAAATCTTAAACCCCTCTCTCCATCAATATTTCACACAAAACATTCCTGGAGACCCCCAGTCACTCATAATTCTTAAGGATCCTGAAATCTCATATATCAGGCCCTGGATTCACCAAATCTGGGATTTATCCCCTCGGGTGAGCTGTATATCTTAGATTGTCTCTCCTGGTCCATTGAGAAATCTAAAGCACCCCCAAAATATTGGGGGTCACCCTGGGACCCTCAAATCTTTGCCTTTTCCCCATTCTGAGGCTCTGAAATTCCTGACAAGCCCCCATAGGGATGATCCCCCAAAGCGGACATCTACCAGAGGTTCAAGGTTTCAGACAGCACCAGGACTCTCAGAATTCTAACACAGCTCTCCCATGCCCCCCACCAAACCGAAGTCCTGGTCACCCCAAGGACCACAGGCCCAATCTCCAAGGGCTTCTGTATGTGCCACAGTTCCCCCCGTCAAGAGTCTGAATTTTTTTTTTTTTTTTGAGATGGAGTTTCACTCTTGTTGCCCAGGCTACAGTGCAATGGCGTGATCTTGGCTCACTGCAACCTTCGCCTCCCGAGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCATGTGCCACCACGCCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACTTGCCTCGGCTTCCCAAAGCGCTGGGATTACAGGCGTGAGCCACCATGCCTGGCCAAGAGTCTGAAATTGTTTTAGCTGGGTGTGGTGGTGTGCACCTGTGGGCCCAGCTCCTCGGGAGGCTGAGGTGGGAGGAGGATCGCTTGAACCCGGGAGTTTGAGGCTACAGTGAGATGAGATCACGCCACTGCACTCCGGCCTGGGCCACAGGGTGACCCTGGAAAAAGTCTCAAAACTTCAGGAATTTCCCCTGGGGATTCCACACCCTGAGACACAGGCCCCTGCAGATCCCAGGGCAGGGGTGCCTGAGACGCTTGTACTTGCCTCAACCCTCACCCCAGATCTGCCCCCACAG
Seq C2 exon
GCTCCACGGCTCCTATGAGGTGATGCGGGGCGGCCACATGAATGAGGCTTTTGTGGATTTCACAGGCGGCGTGGGCGAGGTGCTCTATCTGAGACAAAACAGCATGGGGCTGTTCTCTGCCCTGCGCCATGCCCTGGCCAAGGAGTCCCTCGTGGGCGCCACTGCCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000182472-CAPN12:NM_144691:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=PD(31.9=95.6)
A:
NA
C2:
PF0064816=Peptidase_C2=FE(18.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTTGGCCGCTGGATGGAC
R:
GACTCCTTGGCCAGGGCAT
Band lengths:
273-1830
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)