HsaINT0027449 @ hg19
Intron Retention
Gene
ENSG00000162909 | CAPN2
Description
calpain 2, (m/II) large subunit [Source:HGNC Symbol;Acc:1479]
Coordinates
chr1:223933008-223934867:+
Coord C1 exon
chr1:223933008-223933141
Coord A exon
chr1:223933142-223934698
Coord C2 exon
chr1:223934699-223934867
Length
1557 bp
Sequences
Splice sites
5' ss Seq
CAAGTAAGT
5' ss Score
10.08
3' ss Seq
CGTCTAATCCCCTCTTGTAGGAT
3' ss Score
9.32
Exon sequences
Seq C1 exon
TTCTGGCAATACGGCGAGTGGGTGGAGGTGGTGGTGGATGACAGGCTGCCCACCAAGGACGGGGAGCTGCTCTTTGTGCATTCAGCCGAAGGGAGCGAGTTCTGGAGCGCCCTGCTGGAGAAGGCATACGCCAA
Seq A exon
GTAAGTTGCCATCCTCCCCTGGCCCCATGGCCTTCCCCCAATGCCCTGGATTCCAAAAAATTCACTCATGCCTGTAATCTCAGCACTTTGGGAGGCCGAGGTGGGTGGATCATTTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGATGAAACCCCGTCTCTACTAAAAATATAAAAATCAGTAGAACTACTCCAGGACTACTTTGAGTGGGAAGTCCTTTTCTATAGAAGGACTTCTTTGGCCAAAATTAGGCTCTAAATGCAAGGAGATAGTGCATGCAGGGTGCCTGGCTGCACTGTACGCTGATAAATGATGTCTATCACCATCTTTAACCAAATGCACAGGAACAAGTTATGGTACTGATTGTGCTGGACTTGAGAAGGAGCTCTACTTCCTTGACAGGACACATTTGTATCAACTTAAAAAAGCAGAATTTTTGCCAATGGGCAGAACTATTCATTGCAGAGGTAGGAAACTTGCCCAGAATAGATGATGTCACTGATTAGCAATGGCTTCCCCATCTCCGCACAGCTGCTTCCCACCCAGGTTGCCCACAGTTGAGTTTGTCCAGTGCTCAGGGCTGCCCACTCTCAGTAAGAAGCCCCACACCAGCCCCTCTCCACAATGGCCCCATGTTGGCTGTGCCGCCCGGCTCCTTCCATTAAAGTGACCCCACTTTAGAGCAGCAAGTGGATTTCTGTTTCTTACAGTCCCAATCCAGGAAGGAGGAGTCAGCTGTGAGAACCTGGAGCCTGACGGATGCTTCTAAGTCCCACTGCTCAATACTGGGGTCAGGGAAGCCACCGGACTCCAGCATCAGCAGTCAGGAGCACTAAGCCCTTGCCAACACCGTGCCTGTTTCTCAGAGAAACTGCTTCCATTATTGAATGGTTGTCCTTTTTTAAGCTATCAATGCCAAACGACCCATTAGTAGACCTCCCCTTTCTTGTCAGGATGTAGAAGGAATCAATACAGGAGGTTCATCCAGAAAATCACTAAGGTCCTTCCGACTCTAAGGTTCTACGAGAATCTTTTTTTTTTTTTTTTTTTTTAATACGGAGCCTCATTCTGTCACCCAGGCTGGAGTGAGCGGCATGATCTCAGCTCACTGCAATTTCCACGTTCTGAGTTTCAGCAATTCTTTTGCCTCAGCCTCCCAAGTAGCTGGGACTACAGGCATGCACCACCATGCCCAGCTAATTTTTTTGTATTTTTAGTAGAGATGGTGTTTTGCCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCGCCCACCTCGGCCTCCCAGAGTGCTGGGATTACAGGCATGAGCTACCGCGCCCGGCCTGAGATTTTCTTTAAAACACAAAATACCAGGGAAATGGTAACTGTGGACATTATACCTTGCCTTCCTGAGCACCCCGAGCTGGGAACAAGGCCAAGGAGAATGTGAGCAGGGGGTCCCTGGAGCATCAAATCTAGACGGTACTAGGGGGTGGCTGTTTGAGAGATTATAGCATCAGTAGTGTCAAGGGTAGCGGCAGCGTCTAATCCCCTCTTGTAG
Seq C2 exon
GATCAACGGATGCTATGAAGCGCTATCAGGGGGTGCCACCACTGAGGGCTTCGAAGACTTCACCGGAGGCATTGCTGAGTGGTATGAGTTGAAGAAGCCCCCTCCCAACCTGTTCAAGATCATCCAGAAAGCTCTGCAAAAAGGCTCTCTCCTTGGCTGCTCCATCGAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162909-CAPN2:NM_001146068:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0064816=Peptidase_C2=FE(14.7=100)
A:
NA
C2:
PF0064816=Peptidase_C2=FE(18.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTGGCAATACGGCGAGTG
R:
TGGAGCAGCCAAGGAGAGAG
Band lengths:
298-1855
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)