HsaINT0031160 @ hg19
Intron Retention
Gene
ENSG00000117335 | CD46
Description
CD46 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:6953]
Coordinates
chr1:207940358-207943707:+
Coord C1 exon
chr1:207940358-207940540
Coord A exon
chr1:207940541-207943665
Coord C2 exon
chr1:207943666-207943707
Length
3125 bp
Sequences
Splice sites
5' ss Seq
AAGGTACAA
5' ss Score
6.82
3' ss Seq
AATCAAACTTATTTTTCTAGGTC
3' ss Score
7.93
Exon sequences
Seq C1 exon
TGGTCAAATGTCGATTTCCAGTAGTCGAAAATGGAAAACAGATATCAGGATTTGGAAAAAAATTTTACTACAAAGCAACAGTTATGTTTGAATGCGATAAGGGTTTTTACCTCGATGGCAGCGACACAATTGTCTGTGACAGTAACAGTACTTGGGATCCCCCAGTTCCAAAGTGTCTTAAAG
Seq A exon
GTACAAAGGTTATCTTTTTTCTGTCTTGGTTTGTTATTGTTGTTGCTGTTCATTTTAGACTTTATTTCTTTGATATTAACTATCAGTCATACAAAATAACTGAAAAGAAACAATTTTAGTATTTAACTCTGTCTTGTATTCATTTCTATGCCAGATGAATGACACGAAATTCACATAAAATTCTGCTGTTGTGATTTTTTGTGCTTTTCCAGGGTTCTTAGCACGTTATGTACATTGCATGGGTATATGCTTTTAATATTTTTATGTATAAAAAGTGAATTACAACAACTTTTTGGAATTGAAACATGGGCATTTTTATCTAAGTAAGTCAACAATGGCATAATTCATATAAATGAAATGAGAGCAATAACTCCCAAGTGGTTGATCTTCTAACATTATTTTGTTTCCTAGTGCTGCCTCCATCTAGTACAAAACCTCCAGCTTTGAGTCATTCAGGTTTAGTAGCTTCTTCCTTATATGTCTTCTTCCTTATATGTTACAAGATATAAGGAATTCCTGGAGAAATTGCCAGCAATAACTCCCAAGTGTTTGGTCCAATCTACATTATTATTTTGTTTTCCAGTGTCGACTTCTTCCACTACAAAATCTCCAGCGTCCAGTGCCTCAGGTTTAGTAATTTCCTGCTTATAGTTTTTCAAAAATCCTTTAAATTCCTGGTGATTTTTTATAAAATCCTTCAAATTTCTGGTGATGTTCACTTATTTTTAGTAATGAAAGGAGGGAGGACATTTGTATAGCCATTTTAGTTGTTATACATAGTGATTCTAAAATTATTTGCCATAATCTGATATAAACAGGAATATGACCTTGGGAAAGTTGTATAAATTTTGAATGTGTTTATATATATATGTTTACATTATATATAGAGAAATTGATTTAGTACCTTCCTTATTGGGTATTAGTAAGGTATAAGTGGGATGCATTTAAAGCACTTAGCACAGTGCCTGGTGTAGAGAAAGCTCTTAGAGCTAGCCAATATGACTTATCCTACACTTAAATTAATGTTAGGGAAGGGGAAGGTTCATGTATGTTTGTTAGTATGTGTGTGTGTTAATATGTTAATATGTTTGTTTGTTAATATGTATGTTTTGTGTCATCAACTTTGCTATTTTATTCTTTTCAGAAGTGATCTGTTGACACCTTTACTGAGTTTGTTCCTATTGCAGGACTCTTTCATTTCCTGGAATGCAACTAGTTTGAGTCTTCTGATGTAAAACATTTAAACAGGGAAATTTCTGCTGTCCTCAGAACAAGATCTGTATTTCTGCCTCTTCCCTACCCACCCCTCTTCCACACCTCATAATGTTATTTATTTTTTTTCTCTTTAGTGGGCAGTTTTATCTGGCAATAGCAACTCAATTTTATAGCAACTGAAAGGCAGGAAAAGTCCTTATTTACTGAAATAAAATAGAAGACTTTTGCAGGGACTCCTGGTCAACCACTGTGCTTATGACTGGAGAGATTATTTTGATATGATGGAAGGAATTATCCTGATTTCAGCACTACCATCTCTGGTTTCACTTTGCTTCCAGCAGAAGCAAGAGACAATAGTAATTGTGGGTAGCACTTCAGTCTGGGCAGACTGTGCTTAGTTAACATCATTTCTGTGGTCTTCAGTTTCCCTTTAGTATAATGTGAGTGTTGAACTGAAATCTCAATCACTGGCTTCTAATTTGGTTATATATTTCCTATCTCCCTAATATTTTAAAGGATCGAAGAGAATTATGCATGTTAACATAGTAATTAAGATACCTTCTTATAGGCTGGGTGGGGTAGCTCACACCTGTAATACCAGAACTTTGGGAGGCCGAGGTGGGTGGATCACGAGGTCAGAAGTTCAAGACCAGCCTGGCTAAGTTGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCGGGGTGCGGTGGCAGGCACTTGTAATCCCAGCTGCTCGGGAGGCCGAGGCAGGAGAATCGCTTGAACCCAGTGGGCAGAGGTTGCAGTGAGCCAAGATCATGCCACTGCACTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAACAAAAACCTTCTTATAATTCCTGTAAGAGCTTGGTAACTGGTAGCCTCCTGAGTTGAGTGCTGTAGGGTTTGAGGGGCAGGAAGAGATGAGTTTTTTAGTGGACTGATACATGAGCAAAACAAGATTGCATGTGAAATTTATACTCAGTGAGGCATCCGGGCTTAACTCACATGCTCCTAGTGGGTATATGCACTAATACTACGTTTGTTGATACAGTCTTTTGAAAGAGTTGATGATAAGCATTTCATAAAGTATTTATAAAACACTGGTATAGCTTAGTGTTGGAGAGCAGAAGAGAGAATTGCTTGGGATTGTCAATGATTTCTTATCATCTGCTAGAGGAAGACTAAATAACAACATCATGATGTTAAGGTAGATCTAAATGTGTTAACAAGAAGAAAAGTTGAGGAAGTCCTAAGTGGAAAAGAGAAAGATGTAAATTATGTAGTATCATACTACTTACAGTTTTTAAAAAGATACATATGTTTACCCCAAGCACATTCCCTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCACCCAGGATGGCGTGCAGTGGCGCGGTCTTGGCTCACTGCAACCTCCGCCTCCCGGGTTCAAGCGGTTCTCCTGCCACCTCAGACTCCCAAGTAGCTGGTATTACAGGCACCCACCACTATGCCGGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGATGGCCTGGCTAGTCTCGAACTCCTGACCTCAAGTGATTCACCTGCCTCGGCCTCCCACAGTGCTGGGATTACAGGCGTGAGCCACCACACCCATCCTCACATTACTTTCATGATGGTTATCTTCTAAGATTTCCATTATAAAATACAGAGTGTGGTGAGCATTCTTGTACATACATCTTACATACTTGTGCAAATATATATGTAGGTTAAATTCTAAGATGTGGAATTGCAAAGTTTGTAAAGTGTGTAGTTTTCATTTGATAAACTTAAAAAATCAATATCAAAATTAAAGTCATAATTTTATATTGATAAGGCCCTGGTGAATTTATAAAATCAAACTTATTTTTCTAG
Seq C2 exon
GTCCTAGGCCTACTTACAAGCCTCCAGTCTCAAATTATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000117335-CD46:NM_172353:6
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.586
Domain overlap (PFAM):
C1:
PF0008415=Sushi=WD(100=90.3),PF0200911=Rifin_STEVOR=PU(2.9=3.2)
A:
NA
C2:
PF146101=DUF4448=FE(9.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)