HsaINT0036335 @ hg38
Intron Retention
Gene
ENSG00000159212 | CLIC6
Description
chloride intracellular channel 6 [Source:HGNC Symbol;Acc:HGNC:2065]
Coordinates
chr21:34707944-34708806:+
Coord C1 exon
chr21:34707944-34708069
Coord A exon
chr21:34708070-34708699
Coord C2 exon
chr21:34708700-34708806
Length
630 bp
Sequences
Splice sites
5' ss Seq
GAGGTAGGC
5' ss Score
8.99
3' ss Seq
CCAATTTTGAACTTTTCAAGGTA
3' ss Score
6.15
Exon sequences
Seq C1 exon
GAAACCCGCAGACCTGCAGAACCTGGCTCCCGGAACAAACCCTCCTTTCATGACTTTTGATGGTGAAGTCAAGACGGATGTGAATAAGATCGAGGAGTTCTTAGAGGAGAAATTAGCTCCCCCGAG
Seq A exon
GTAGGCCTCAGAAAACCAGTGTTCATAACTTGATTGTCACTTTCCCCCACTAGTAGTCAGTTCTAAAGCTCTGGGCAGTGTGTGTGTGTGTGGTTTTCTGCAGCCCACGGTGCTCACTTCCTTAATCATAACCCTGGTGTAACCAGATTAGAGTTCGGGGACCTGGGTTTCATTGTGCTGCACCTGCAGCTTGGCAATCACAGTTTGATGGCAGGAAGTGGGAGGAGATGGGTCCAGGGTGGGTGGTTGGCTGTATCCTAGACACCCTGCTGGAAGCTATGGAGTATGTGTTAGGAAGAAGTATCATGGATTTTTGGACCTCGGGGGAGCTATTTCTACTCCATCCCCTTCGTTTTACTAGGGAAGCACCTGAGACCAGCAAGGCCAGGTGGGGTCCTGTGTCCCAGAACTGGCCACTGCCAGGAAACAGCAACAATCCAAACCTCTCCGTCCAGTGCCATTCTCCTAGATGTTGTTACTTCCCAACCTTTGAGAGGAAAAGGGTCAGGAAAACGTTGAAGGAAAGCTTTTCATTTTTATGCCCAGAGAAAGCTGTTTTTCTCCATTGTATAGTATTATCTTCACTAAAACATCACTTGTCTGTGATCCTCCAATTTTGAACTTTTCAAG
Seq C2 exon
GTATCCCAAGCTGGGGACCCAACATCCCGAATCTAATTCCGCAGGAAATGACGTGTTTGCCAAATTCTCAGCGTTTATAAAAAACACGAAGAAGGATGCAAATGAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159212:ENST00000360731:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.302 A=NA C2=0.234
Domain overlap (PFAM):
C1:
PF134171=GST_N_3=FE(57.5=100)
A:
NA
C2:
PF134171=GST_N_3=PD(0.1=0.0),PF134101=GST_C_2=PU(17.5=48.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGACCTGCAGAACCTGGCTC
R:
TCTCATTTGCATCCTTCTTCGTGT
Band lengths:
224-854
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development