HsaINT0036453 @ hg38
Intron Retention
Gene
ENSG00000179335 | CLK3
Description
CDC like kinase 3 [Source:HGNC Symbol;Acc:HGNC:2071]
Coordinates
chr15:74624902-74625968:+
Coord C1 exon
chr15:74624902-74625018
Coord A exon
chr15:74625019-74625801
Coord C2 exon
chr15:74625802-74625968
Length
783 bp
Sequences
Splice sites
5' ss Seq
GTTGTGAGT
5' ss Score
6.59
3' ss Seq
TGCCCATCCTCCTCCTCCAGCCT
3' ss Score
8.2
Exon sequences
Seq C1 exon
AGGGAAGTCTCAGGTTGCCCTGAAGATCATCCGCAACGTGGGCAAGTACCGGGAGGCTGCCCGGCTAGAAATCAACGTGCTCAAAAAAATCAAGGAGAAGGACAAAGAAAACAAGTT
Seq A exon
GTGAGTATCTGCAAGGAGTGGGAGGGAAGCCTTCAGTGGGGCTGCTGGACCCCCAGGGGCTTAGTAGTGTGCCTTCACCCATCCGCACTGTGCCTTCTCCCCACACTCAGAACCAGGGGAGTGTGGCAAAGGTCTTGCTGGAAGCCTTTAGACTGCAGTCCAGTCTTCACCCCAGCTGTCTCTGTGTCCTGAGGAAGGCCTCCCAGCCCTGCGTTTTGTGAATTGGGGAGCTCACTGGGTTATGCTGGGCATAAAACAAGATAAAAACATGAAGTTGGGGCTCTCACATAGTAGGAGATACCCAAAGGAGGGCCTTTCTGTGGCAGACACACTGAGCACTCTCCTCCACGCACTGTGCTGAGCCTGGGCAGATGGGTGAATCCAGCACAGACCCTCACGAAGCTCAGCAGAGTGAGCAAGTGGAGAAAAGCAGCACCAGTCCTGCGGAGTGCACTAGCACTTTCCATCTCTCCCTCAGCAACTCTGAGGCAGGGCTGCTTCCATATCATAAGTAGGGAAGCTCGGAGGGCTTGGACCAGAACCGTGGACATCTCCCCTACCCCCCGCAGGAAGCTTAGTCCTTGCCCAGAGCTCATCTGGGTATTGGGTGATGGCTGGTGGGGAGAGGTGCTCTTGCTCTGATTTCTCTTGCACTGTGTGTATCTGCATTCTGGTGTGTGACCCGGTGGCCTAGGAGAGAGTTGGGAACTGTCTTCATCTGAGAGAGGGGGTGAGGCAGGCCCCCAGCACACAGCCTGAGCCCTGCCCATCCTCCTCCTCCAG
Seq C2 exon
CCTGTGTGTCTTGATGTCTGACTGGTTCAACTTCCACGGTCACATGTGCATCGCCTTTGAGCTCCTGGGCAAGAACACCTTTGAGTTCCTGAAGGAGAATAACTTCCAGCCTTACCCCCTACCACATGTCCGGCACATGGCCTACCAGCTCTGCCACGCCCTTAGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000179335:ENST00000345005:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.029 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(12.3=100)
A:
NA
C2:
PF0006920=Pkinase=PU(27.3=98.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGAAGTCTCAGGTTGCCCT
R:
ATCTAAGGGCGTGGCAGAGC
Band lengths:
283-1066
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development