HsaINT0037403 @ hg19
Intron Retention
Gene
ENSG00000044459 | CNTLN
Description
centlein, centrosomal protein [Source:HGNC Symbol;Acc:23432]
Coordinates
chr9:17462914-17464621:+
Coord C1 exon
chr9:17462914-17463011
Coord A exon
chr9:17463012-17464494
Coord C2 exon
chr9:17464495-17464621
Length
1483 bp
Sequences
Splice sites
5' ss Seq
AAAGTATGG
5' ss Score
3.77
3' ss Seq
TCACCTTTTTTTTTTTCAAGGAT
3' ss Score
10.01
Exon sequences
Seq C1 exon
AATGCTACTAATGAACTCACTAAACAGTCATCAAATGTGAAGACTTTGAAATTTGAACTCCTAGCAAAAGAAGAACACATAAAGGAAATGCATGAAAA
Seq A exon
GTATGGTTTTTGTATTTCTATCCATTGTATTTGGTGCCACCTAGTGGCAACCAGCTCTATTAAACGTGCTCCAAGAAACTGCTAATGTTTACGTTTTCCTTCCCTAGTTCATATTTAAACCTACCTAAGATGAAAGTTTAAGGAATACTATGTATAGCATGATTAATGGCAAGCTATTTACTTTTTTAAATTAGATAATGATGAAGTTAAATTTCCGTTATTAAACATATTTAATTTTGAATAAATACAAATTAATGGCTTCGAGACAATGAATGAAAAACTTTACAACGTGGTGGTTATTTGGCCCCCCAAATATATGATTAGTATTTGTATTGGATTTAATGCCTAAGCTTATAAAGCTAAGGTAAAAAAAGGAAAGTTTTGTTTGTGTTTAAAATAACTGGAGGTTATGGAAGTTTGTACTCTTGTGTTTATCAGTACAAAGATTTTAAATGCTCTATCCCACTGAATCAAAATTATTTTCTTTCTGTATCTTTCAAAGCTACACTATTGCTTAGAAATAGTAAGATGTTTAGATAGAATTCCAGTTGTCACTGATACATTTGAGATATATGTATCTCACAAACACACCTGTAGACCTCATTATAAGTGAAGAGCACTTAAAAGTGATATGAATAGATAAAAGCATTAGACAAAAAGCTTGGTTAATTTTTTAACTGATAATATTTTGAAGTTTATTTATCAATTAAGAGTAAGTCTTGCTTATTGTTTAACAGGGCTCTAGATTAACACTCTTTGAATCCTGGCTTCCCTACCTACTAGGCCTATGCCTAAATTTAATAATATTAAATTAGGTTCTTACGAGGAATAAATGAGTTAATACATGTAAAGCACTTATAACAGTGACTGGAACATTGTAAGCCTTCGATACATGTTAGCTATTGTCATTCTTGTTTTAGTAGTAGCAGCAGCAGCAGCAGCAGTAGCAGTGGTTCTCACAGCATCTACCATTTTATACTTAATAGTTCATCAACTTATGCTAAACAGCTGTGTGGATTGAATCTCAAATTATATTAAATTAGAAGATATTATGGCTAATTTAGTTTCATTACAAGAGTTTGCATTTGTTTATTGAAGTATAAGATTTTTTTCTTATCATTTTTATGCTTTTGATTATCTTCATATATCACTTTGATTTTTCACAGCAATGTAAAAATGTAATTTAAATGAAATAGTTCTAAGTTTTCATAAGTGTTATTAATTTTTCTCATTTCTTATATATTTTGTTTTAATACATATATGTAATTATATAATTACCAAGTCACAACTATAGATTTTACAAGTGTTCAAAATATTAAAAGAACAATATCTTATGCAGTGCAATTCATTTTACTGATTTACAGTGTCAATATCACGTAGCATTTAAAAAGTAACAGTAGGTATAATATTGGATAAAATGTAAGATATCACCACTGTTAAGGTATTTTCTGTCACTCTTGATGTCACCTTTTTTTTTTTCAAG
Seq C2 exon
GATATCTCGAATGGAGAGGGATATAACTATGAAAAGACATTTGATAGAGGACTTGAAATTTCGACAGAAAGTAAATTTGGAAAGTAACAAGAGTTTTAGTGAAATGTTACAAAATCTTGATAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000044459-CNTLN:NM_017738:20
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.182 A=NA C2=0.140
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTACTAATGAACTCACTAAACAGT
R:
TCACTAAAACTCTTGTTACTTTCCAA
Band lengths:
198-1681
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)