HsaINT0040239 @ hg19
Intron Retention
Gene
ENSG00000145244 | CORIN
Description
corin, serine peptidase [Source:HGNC Symbol;Acc:19012]
Coordinates
chr4:47602231-47605685:-
Coord C1 exon
chr4:47605414-47605685
Coord A exon
chr4:47602365-47605413
Coord C2 exon
chr4:47602231-47602364
Length
3049 bp
Sequences
Splice sites
5' ss Seq
AAAGTAAGC
5' ss Score
7.31
3' ss Seq
CTTATTTTTTAAAAATTCAGTGC
3' ss Score
4.32
Exon sequences
Seq C1 exon
GAGAGAGAATGCTGCAGTTTGGAAAGTGGTGCTTGGCATCAACAATCTAGACCATCCATCAGTGTTCATGCAGACACGCTTTGTGAAGACCATCATCCTGCATCCCCGCTACAGTCGAGCAGTGGTGGACTATGACATCAGCATCGTTGAGCTGAGTGAAGACATCAGTGAGACTGGCTACGTCCGGCCTGTCTGCTTGCCCAACCCGGAGCAGTGGCTAGAGCCTGACACGTACTGCTATATCACAGGCTGGGGCCACATGGGCAATAAAA
Seq A exon
GTAAGCCAGTGTATTAGTCCATTCTCATGCTGCTATAAGCACATACCTGAGAGTGGGTAATTTATAAAGGAAAGAAGTTTAATTGATTCACAGTTCTGCAGGGATGGGGAGGCCTCAGGAAACCTACAATCATGGCGGAAGGGGAAGCAAACATGTCCTTCTTCACATGGCAGCAGCAAGGAGAAGTACTGAGCAAAAGGGGGAAAAGCCCCTTATAAAACCATCAGACCTCGTGAGAACTCACTATCAAGAGGGTAACTGCCCCCCATGTTTCAATTACCTCCCACCAGATCCCTCCCATTACACGTGGAGATTATGGGAACTACAATTCAAGATGAGATTTGGGTGGGAACACAGCCAAACCATATCAGCCAGGATCTTCAGGAGCCTGAGAAACATTGTGTTCCTCAGTTGGGAGGCTGAGGTGGGAGGATTTCTTGAGCCTGGAAGGTGGAGGCTGCAGTGAGCCAAGATCTCACCACTGCCTGGGTAACAGAATGAGACCCAGTACCCAGACCCAAAAGCTAGGTAGCTTTTGGCCGTAATTTCCCATTTTCTCTTACAAAAATATAGCCACAAATGGTAAATACTTAGCGATGTGTCACACTTCATCTGCTGTGCAAATCATAGACATTAATAATGAACCATGGCATTTAAAATGGCCAAGCTCAGATGCAATCTCAAAAATCCCTCTCCACACTTCAGAATCTCTCTCTGGGAGCTTACTATTAATGTTTTGGAGCTTCCTTGTGGCAGGAGGAGACCTGTCACTGAACTGTGCTTTGGACTCTCTCTATCTGCCTGCAGATAGCCCAATGATAGAGACAGTCACTGGGAATCTCTGCAGTCAAGCTGCATGGTCATATTTCCAATTCTATGTTGTGATTTGGTCTTATCAACATCTGTAGTACAAACTATAAATCCTTCAAGAAAGTATATTGATTTGCTATTTGACTATTTAAATTGATTAAAATAGTTTGGCTCTGTAGATGACTTAACATATAAAACACATAGAAATTTAAAATGTGTACTCTGTATTTACTCTAAACCCCTATAATGGACTCTCTCATTCAGTTTGACCTACTTTAGAAATAATAATTGTTTGTTTGTTTATTTGTTTGTTTTTGAGACGGAGTCTCACTCTGTCACCCAGGCTGGAATGCAGTGGCACAATCTCGGCTCACTGCAACCTCCACCTCCCAGGTTCAAGTGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGACATGTGCCATGACGCCTGGCTAATTTTGTTTTTTGTATTTTTAGTGAGACGGGGTTTCACCATGTTGGCCAAGCTAGTTTCAAACTCCTGACCTCAGGTGATCCACCCACCTGAAACTTAAAAAAAAAAAACTGTAAGTGCTGCCTACTCTGTCCATATCAAGTATAATGCCATGGCTTTCAAGAATAATAATGTATATTGGCATTCTGTTATTGGCCTTAGAAATTGTATATTTGAAGGAATTTTTTCTTAAAATTTAGTCAGATAAGGTTTGACTTACATTGAGTTTCTTTTCTATTTCATCAATTACAGAACAGAAAGGAAATTCAATAGGCAGAAGTCAATGACTTTTTCAAAAAAACTCACATGTAACAATTTTGAAGGCAATGTTAGACATGCTGTCACCACTCCTATGCATCTGTTTTTTTTCAAAGCTATGATTAATTCTGTAATTTAAGAGCAGACTATGCTTGATATTGTTTCTGCTTATATTCCTCCTACAATATCCATATTGAACTCAGAGCAATAGTGCAACATAACGCACACTCCACACATGTAGTATAGCATGAATTGAGCCCAGGAGTTCAAGACCAGCCTGGGCAACATGGTGGAACTCTGTCTCTACAAAAAAAAAATTAGCTTGGCATGGGGGTGTGTGCCTGTAGTCCCAGCTACTTGGGAGGCTGAGGTGGGAGGATTTCTTGAGCCTTGAAGGTGGAGGCTGCAGTGAGCCAAGGATTTCTTGAGCCAAGGTGGAGGCTGCAGTAAGCAAGTGACCACTGCCTGGGTGACAGAATGAGACCCTGTCTCAAAAAAAAAAAAAAGATCTGCTGAATTCAGTCAGAAAGACCTGACTGATCTGACTGTATAACTTTCAAGCTTACTATAAAATGGAAAAAAATAGCAACTACCTAACTCACAGGAGTATTGTAAAGATTAAAGGCAATGAGACCCACTAGTGCCCAATAAATGTTAGCTATTGTTCTTATTCTTTTGACAACCTGTGAAACATCCACTGTCTGCATCACATTGATTTTCCTAAAAATGGCTCTTTCTTCCAATAAGGTACCCAGTAGTGCTTCACCATCACTGTTTAAAAGAAGAACAGTGTGTATAATTTTGCAGAATGGCTAAACAGTGAAAGATTCATGCTGTCTTGCTTCAAGAAATCCATTGTCATTCTTCAAGAACTTTTAAGCAAGATGGAATTCACATATTCTCTCTGTCAATACCAAGGGATGGCTTTGTGCTTTTCGATATCTCTCTGTCATATCCTCTAGGATTAGAGGTTCTTACATCAAGTAATGGCTGCTGGGGCACATATTGAGGCATATTCTTTTCATCAAGAATAGGACAACCCTTCCCTGTTAGATTAAACAGGTTTTCTCTACTTTAGCAGAGCAGGACTATCATGCTGAGTTGACGCCGAGCTGGCAGCCTCCTATCTGGCAGCCAGCAGAGCTCTGGCTTGATTTTTTTCTTTTCTTTGTAGTAGCTATTGTTTTGGTTGTAGCATATGGTAAGGATGAACCAACTTACTTAACCAGTCTAGGCCTTGGTTTACCCATTAATAAAATAAAGGAGTTTCACCGGATAATTGCTATGAATGCTTCTAACTAGAAAATTCTGATTCCAAACCAGCCATGTCTTTAAAATGGCATTTCAAGTAAAGAATATGCCTCTCTTGGTATAAAAATATTTATATTATATTTGCATTTCATATTTGGCTAGCCTCACTAGCCTCACTTTTGAGTCATTTTATCATCATATATATATTCTTATTTTTTAAAAATTCAG
Seq C2 exon
TGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGGATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145244-CORIN:NM_006587:20
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(39.7=100)
A:
NA
C2:
PF0008921=Trypsin=FE(19.2=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)