HsaINT0040240 @ hg19
Intron Retention
Gene
ENSG00000145244 | CORIN
Description
corin, serine peptidase [Source:HGNC Symbol;Acc:19012]
Coordinates
chr4:47596018-47602364:-
Coord C1 exon
chr4:47602231-47602364
Coord A exon
chr4:47597921-47602230
Coord C2 exon
chr4:47596018-47597920
Length
4310 bp
Sequences
Splice sites
5' ss Seq
ATGGTAAGT
5' ss Score
11.01
3' ss Seq
CCCATCGTTACTTATTGCAGGGT
3' ss Score
6.96
Exon sequences
Seq C1 exon
TGCCATTTAAGCTGCAAGAGGGAGAGGTCCGCATTATTTCTCTGGAACATTGTCAGTCCTACTTTGACATGAAGACCATCACCACTCGGATGATATGTGCTGGCTATGAGTCTGGCACAGTTGATTCATGCATG
Seq A exon
GTAAGTTGCTTTCTGGTTACCAAGGAGATTCAGTTCAACAATAACTTCAGTGGATTCCTATAAACTCATTATTACGTATGGCCCTTTGGAAACATTTTTTGAAAATCATTTGTTGCCAAATGTTTAATTATTAACAGCACATTTTCCTGCAGCTGGTACACAAGCAATCCCCACAATTACACCCATCCTCTTTATTCAGGGTGCCTTCTACTGTCTCATCTACTATATGGGGAACATCACCCTTGTTCAGCAACAGGAGAAAAACAATTTTTCCTGTTCATCTCATTCAACCATTTTAGTGGCTAGGATAAATGAGGTTCTAAGAGGAGCTAGTAGTAACCATGGCTTCCACCTGGCTGCCCTGGGGAAGCAGGGAAGGCATGAAAGGACATTGTCAGCCATTAGGGTGATGGCAGGAAGCCACACATCAACACCCCAACTTCCAGGGTGTGAGACAGGACTACCTCTGTCTCAGGGGTCATCACACTGGTGTTGTCTGGGCCCTCACTTGATTGCCAGCATGTCCTCAAATGTCACTGAACTCAACCTTTAGATACTCAGGATTCATGGCCATGAGAGTTTGCAGAACATATTAACATAATAGTGTAGAGGTGCCTTTTTATTTTTACTTAATAGACACACATCGAACATTATACTGGACTGGCTCCCAGGAAAGGAGGGAAAAGTGCAAGTGCTCAAATAAGCTTGTAACAAAAACTGGGGAAGACAGTTATTATACTATGCTGCTGTGAAGCACCTTTAATTGGGAGTAAATTGCTCCCTACAGTTTAGTAATGAAGAAAAGATACAACAGTGCTCTTAAGTACTAACTCAATTTAAATAAACTATATTTTTGATGATCCATTTTAGAATGGAAAAATCAGGGTATTGAAAATGGCCCTGTGGTGATTCCTTAGATAGTTGTCATGGGAAAGAGGGAGGCAGACAGCTCCCTTGGCATTTCGCTGAGACCACCCTCCTTTCTGCTTCATGGCCACAAGTCATCCTGCTGACGTGGATGGTGGTAAAGGAATCCCTCCCTTCTCTACAGGAGGACTGGGTTTGATTTCCCAGGCCCAAAATAAAGTGTTGTAGGAGGCAGCATGATGTGGGTGTGGGGCACAGGATTTGAAGCCTGAAATATCTGGGTTGGAATTCATCTCTGCCAGTGAGACCAGTATAACCCGGGGAAGTTATCTAACCTCTCTAGATAGCTTTCTCATGAGTAAAATGGGACTAATTCTGTCCATGAGGATTAACTAAGTGAATGTATTTGGAAGCCCATATCTTTCACATATCTGTATATGATATCTGGCACATACTTAGACATTCAATGAATAGTAATTACACCAATATTAACAGCTATCAATTTAGTGCTTATTATGTTTCGGGCTCTCTGCAAAACGCTTTCTAATAACTCATTTAATTATCACAATCAACCCATATGGCAGTGTCTTTATTTTCCCTAAACAGATCAAGAATACAGGAGGTTAAGTAATTTGCCCCAAATCAGCCAGCATGAAGGTGGTAGACTGAGGACATGAAACCAGTCAGTCTGGCAGCAATGATTAATATAACTACATTTCTTCCTCTCTCCAATGTCATTTGGAGGTTTACCAAAAACTAGCACCTCTTGGCACATGTTCAAGATCATCTCTTGGCAGTTGCTAAAGGAGGGGAAGGGAGATGATTCCTTGACAGAGAGCTGAAGGCCCACAGACACAGGCATGGGCATGTTCTTATCATGATGCCTAATAGGAACCAGGTCTTGCCGACTTCTTTAGTAGTGGGAGTTCAGTGGTGTATACTGAGTTCAGTGGAAGTTCATTTAGTACTGGGTATACTAAATGCATACCAGATATTCTCTAACACAACTTCAGGTAGAAAACCAAACAAAACCTACTTTTTACTATATCAGGAGCAAATTTTTCTACTTAGACCTCTATTATATGACAGATATTATTTTCCTTAATTGTATCAACAGGACATAATGAAGCGTGAGTTACTCCGTGACAATCTATAAACCTGAATACTGAATACTGAAGCCAAATATAAATGTTGGTTTCAAGCCCAATATTACAAAGAGGACCAAAAGAACAGACCAGATCAGTTGTGCCTTTAGCTGTAGTCTCCCTTTCATTTTTAATTGCTTGCTTTTCACCTTTCATTTTGCACTTAATGGGGTGCCTACCTGACTCACTAAGCCTAACTCAAAACCCACATCTCAGGAAGGCATTTTTTATTCCTCTCCACCTGGAAGTCATCACTCATTCCTTTGACCTCCTCTTTCTAGCCATTAGATTTTGCTTTCATGTGGTTATCCTTGTTACCCAAGCTGACTTTTGGCTGTTCTGGGACAAAAACAGTGCCTTATTCGTTTGTTTATACACTAGCACAGAACTTTGCAAAGAGTAGATGCTAAATAATTATTTTACTAAATGTCTGATCTGGAAGTGAAAATGTGCTGACATTCTAAACACATTCCATTTTAATCACCCTCTGACATAATAGTTCCACTTCAATAGCTGAGCATCTTATTTATTTTATATAAGGAGAGATCAAGAATGAAATACCCTATGCATATGAAATGTGTGAAAACAAATTTGTGAAAATAATTTGTGAAATGTTTCCAGGAAATTTTTCTTTTTCGTCTAAGCATTATATACATGTAACAAAGAAATTTTGCTTTAAAAAAATTCAATTAGGCTCTTAGGCAGAAAAATTCAGCTCCTTGCAAGTTCTATGCTTATGATTTTGGCTTAGGGTATTGGAAAGTTACAAATTTAAAGATCATCACTTACACAAAAGCATACAGCACAATCAAAATTTTAATCTCTTTCTTCTTCTTTTTTTTTTTTTTTTGAGATGGAGTTTCACTCTGTCTCCCAGGCTGGAGTGCAGTGGTGTGATCTCAGCTCACTGCAACCTCCAACTCCTGGGTTCAAGGGATTCTCCTGCCTCAGCCTCCAGCGTAGCTGGGATTACAGGTTTCCACAACCACACCTGGCTAATTTTTGTATTTTGAGTAGAGACAGGGTTTCACCATGTTGATCAAGTTGGTCTGGAACTCCTGACCTCAAGTCATCTGCCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCTAGCACGCCGGGCCTAATTTCTCTTTCATAGCAATAATATTCCCTAATATTCCTAAGAAGCAGGGTAGCCTAGTAGTTATAGAGTTGGAATCCTGTTACCAGACTGCCTGGATTCAAATCTAGCCTCTGCCAATGAATAAGTTATTTAACCTGTGCTTCTGTTTCATCATCTCCAAAACAGATATAATAAATAATATAAACTCTTAGGTATTTTGTAAAGATTAAATGAGCTAATATGTGGAAAATGTTTAGAAGAGGATCAGGAAACATTAGTCCTATGTTCTTCAACAATACCAAGTAGGAAGACCATAGATATGCTTCTAATTTTGAAAGTCTTGTAGGTCAAGGAGTATTTGTAACCTTCCACAATGAATTCACGTATTTACTCTTTTATTTTCCATGATATCAGCTCTTCTTTTTTGAGGCAGTGCAGAATACACCTTTGTTTTCAGATGTAGCAAGTATTGCTATCTCTAATGCCATAGCATTTTATCATTAACTATATTTGGGGGAAAAACTGAATATAGTTCAACTGGAATCCTTAAATATCATGAATGAAAATCCCTATATATATGAAATAAAATACAGGCTATTAATGATTCATTATAATTTTAAGTGGTCTTATTTTGTATTCAACTATGCCAAATTAAAAAGTCCTAAGAACTATTAAGAAGTGTAGTAAGGGACCCCAAATTGTGTTATGCTTAATGTATTCATTCACAAAGCAAGAATCTTGAAAATAGATATTTTAGAATATGTTTGCAGTACTGTGTGTGGGGGGGATCTTTATTCCATTTTGGGTACTTTCCACAGTCATAAGTCAAGCTTAAATTAGAATGAGGTCAATTTTGAGGTAATTAGTTCTGATACTTTTTAAAAACTTTATGACATATTTTTATAAGTGCAGAAAATGCCTGAAAAAGGTAATTTCCTGGGGGAAAAATATAATTTCTTCCCAAGCCACTCCACCCTTTTAATGATCAGAGTTTAAGATGTTTATTTGAAAGTTCTGTTTTTACAGTGGAAAGCACAACTCCTCCACAGGCTGACAAGGAAAGCTTTGTTGAAACTTTCCAAGTTGGTTAATCTGGGTTTAGCTTTATAGTATCCTCAGGATAGCATGGACACACATTACTGCCCTGAAATGCCAGTTCCTAACTCCCATCGTTACTTATTGCAG
Seq C2 exon
GGTGACAGCGGTGGGCCTCTTGTTTGTGAGAAGCCTGGAGGACGGTGGACATTATTTGGATTAACTTCATGGGGCTCCGTCTGCTTTTCCAAAGTCCTGGGGCCTGGCGTTTATAGTAATGTGTCATATTTCGTCGAATGGATTAAAAGACAGATTTACATCCAGACCTTTCTCCTAAACTAATTATAAGGATGATCAGAGACTTTTGCCAGCTACACTAAAAGAAAATGGCCTTCTTGACTGTGAAGAGCTGCCTGCAGAGAGCTGTACAGAAGCACTTTTCATGGACAGAAATGCTCAATCGTGCACTGCAAATTTGCATGTTTGTTTTGGACTAATTTTTTTCAATTTATTTTTTCACCTTCATTTTTCTCTTATTTCAAGTTCAATGAAAGACTTTACAAAAGCAAACAAAGCAGACTTTGTCCTTTTGCCAGGCCTAACCATGACTGCAGCACAAAATTATCGACTCTGGCGAGATTTAAAATCAGGTGCTACAGTAACAGGTTATGGAATGGTCTCTTTTATCCTATCACAAAAAAAGACATAGATATTTAGGCTGATTAATTATCTCTACCAGTTTTTGTTTCTCAAGCTCAGTGCATAGTGGTAAATTTCAGTGTTAACATTGGAGACTTGCTTTTCTTTTTCTTTTTTTATACCCCACAATTCTTTTTTATTACACTTCGAATTTTAGGGTACACGAGCACAACGTGCAGGTTAGTTACATATGTATACATGTGCCATGTTGGTGTGCTGAACCCAGTAACTCGTCATTTGATTTATTAAAAGCCAAGATAATTTACATGTTTAAAGTATTTACTATTACCCCCTTCTAATGTTTGCATAATTCTGAGAACTGATAAAAGACAGCAATAAAAGACCAGTGTCATCCATTTAGGTAGCAAGACATATTGAATGCAAAGTTCTTTAGATATCAATATTAACACTTGACATTATTGGACCCCCCATTCTGGATGTATATCAAGATCATAATTTTATAGAAGAGTCTCTATAGAACTGTCCTCATAGCTGGGTTTGTTCAGGATATATGAGTTGGCTGATTGAGACTGCAACAACTACATCTATATTTATGGGCAATATTTTGTTTTACTTATGTGGCAAAGAACTGGATATTAAACTTTGCAAAAGAGAATTTAGATGAGAGATGCAATTTTTTAAAAAGAAAATTAATTTGCATCCCTCGTTTAATTAAATTTATTTTTCAGTTTTCTTGCGTTCATCCATACCAACAAAGTCATAAAGAGCATATTTTAGAGCACAGTAAGACTTTGCATGGAGTAAAACATTTTGTAATTTTCCTCAAAAGATGTTTAATATCTGGTTTCTTCTCATTGGTAATTAAAATTTTAGAAATGATTTTTAGCTCTAGGCCACTTTACGCAACTCAATTTCTGAAGCAATTAGTGGTAAAAAGTATTTTTCCCCACTAAAAAACTTTAAAACACAAATCTTCATATATACTTAATTTAATTAGTCAGGCATCCATTTTGCCTTTTAAACAACTAGGATTCCCTACTAACCTCCACCAGCAACCTGGACTGCCTCAGCATTCCAAATAGATACTACCTGCAATTTTATACATGTATTTTTGTATCTTTTCTGTGTGTAAACATAGTTGAAATTCAAAAAGTTGTAGCAATTTCTATACTATTCATCTCCTGTCCTTCAGTTTGTATAAACCTAAGGAGAGTGTGAAATCCAGCAACTGAATTGTGGTCACGATTGTATGAAAGTTCAAGAACATATGTCAGTTTTGTTACAGTTGTAGCTACATACTCAATGTATCAACTTTTAGCCTGCTCAACTTAGGCTCAGTGAAATATATATATTATACTTATTTTAAATAATTCTTAATACAAATAAAATGGTAATGGTCTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000145244-CORIN:NM_006587:21
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(19.2=100)
A:
NA
C2:
PF0008921=Trypsin=PD(20.5=77.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)