HsaINT0041235 @ hg38
Intron Retention
Gene
ENSG00000148204 | CRB2
Description
crumbs 2, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:18688]
Coordinates
chr9:123373134-123374695:+
Coord C1 exon
chr9:123373134-123373920
Coord A exon
chr9:123373921-123374578
Coord C2 exon
chr9:123374579-123374695
Length
658 bp
Sequences
Splice sites
5' ss Seq
CAGGTGGGA
5' ss Score
6.71
3' ss Seq
AGCCTCTGCTCTCTCCCCAGGTT
3' ss Score
10.76
Exon sequences
Seq C1 exon
GTGTGGCGGAGGCCACGTTCCGCGAGGGTCCCCCCGCCGCGTTCAGCGGGCACAACGCGTCGTCAGGGCGCTTGCTCGGCGGCCTGTCGCTGGCCTTTCGCACGCGCGACTCCGAGGCCTGGCTGCTGCGTGCCGCGGCGGGCGCCCTGGAAGGCGTGTGGCTGGCGGTGCGCAATGGCTCGCTGGCGGGGGGCGTGCGCGGAGGCCATGGCCTGCCCGGCGCTGTGCTGCCCATACCGGGGCCGCGCGTGGCCGATGGTGCCTGGCACCGCGTGCGTCTGGCCATGGAGCGCCCGGCGGCCACCACCTCGCGCTGGCTGCTGTGGCTGGATGGTGCCGCCACCCCGGTGGCGCTGCGCGGCCTGGCCAGTGACCTGGGCTTCCTGCAGGGCCCGGGTGCTGTGCGCATCCTGCTGGCTGAGAACTTCACCGGCTGCTTGGGCCGCGTGGCGCTGGGCGGCCTGCCCCTGCCCTTGGCGCGGCCCCGGCCCGGCGCGGCCCCTGGCGCCCGAGAGCACTTCGCGTCTTGGCCTGGGACGCCGGCCCCGATCCTCGGCTGCCGCGGCGCGCCCGTGTGTGCGCCCTCGCCCTGTCTGCACGACGGTGCCTGCCGTGACCTCTTCGACGCCTTTGCCTGCGCCTGCGGCCCGGGGTGGGAAGGCCCGCGCTGCGAAGCCCACGTCGACCCCTGTCACTCCGCCCCCTGCGCCCGTGGCCGCTGTCACACGCACCCCGACGGCCGCTTCGAGTGCCGCTGCCCGCCTGGCTTCGGGGGCCCGCGCTGCAG
Seq A exon
GTGGGATGGCTGGGCAGGGGGGTGGGCTGCGAATGCCCCCTGGGGCTATGGTGGGGCAGAGAAGTCTGCCAGGTCTGTGGATGAGTCGCTTCCCTTCCCTGGTCCTCATGTCCTTATCTGTGACATGAGGAGGACAGTTTAATTTGATAAATTTCCTGATAAAATACAGATCAAAACACAACCAGTTAGCCTGGAATTTCAGATAAACAGCGCTGTGGTCTGGGGCTGGGAGCCGCCTGCCGCTTACACGGAGGTTCATCCCTATTGGTGGCTGGTTGGGGTGGAGGGAGGGGGTCAGGCTTTGGCGCTTCCCTTATTCATCTGGCAGTGGCTCTCCCGGGAGCCCAGCGTGTGGAAGGGGATCTGGCTGTGGCCTGACCCCTCCCTCTCCCCTCAAGGAATGTCCAGGCGTTGTGTTTAGGAGCTGCTTTTGTTCAGAGTCCTTACACTTTGTTGTCCTGAGTCCTCTGAGACTCTGGAAAGCGAGTGCAACCCTGTGTCCCTTCCCTCCCATCAGGGACCTCAATCCCATGCCCAATAGAGGAAGGCCCTGAGTTCCATACATGAGAACACAAGCTCAGGTGGCCCACGGTCACAGCGCTGGGGAGGGCAGGTCCCAGGTGTCCTGCACCCACTCCAGCCTCTGCTCTCTCCCCAG
Seq C2 exon
GTTGCCTGTCCCATCCAAGGAGTGCAGCCTGAATGTCACCTGCCTCGATGGCAGCCCATGTGAGGGTGGCTCTCCCGCTGCCAACTGCAGCTGCCTGGAGGGTCTTGCTGGCCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148204:ENST00000373631:10
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.041 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0221019=Laminin_G_2=WD(100=43.2),PF0000822=EGF=WD(100=10.0),PF0000822=EGF=WD(100=11.3)
A:
NA
C2:
NO
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACTTCGCGTCTTGGCCTG
R:
GGGAGAGCCACCCTCACAT
Band lengths:
348-1006
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development