HsaINT0041239 @ hg38
Intron Retention
Gene
ENSG00000148204 | CRB2
Description
crumbs 2, cell polarity complex component [Source:HGNC Symbol;Acc:HGNC:18688]
Coordinates
chr9:123365917-123366366:+
Coord C1 exon
chr9:123365917-123366112
Coord A exon
chr9:123366113-123366226
Coord C2 exon
chr9:123366227-123366366
Length
114 bp
Sequences
Splice sites
5' ss Seq
CGGGTGAGC
5' ss Score
8.19
3' ss Seq
CGCCGGTGCGCCCTCCCCAGGTT
3' ss Score
8.2
Exon sequences
Seq C1 exon
GCGTGACCTGCGAGATGGAGGTGGACGAGTGCGCCTCAGCGCCCTGCCTGCACGGGGGCTCGTGCCTGGACGGCGTGGGCTCCTTCCGCTGTGTGTGCGCGCCAGGCTACGGGGGCACCCGTTGCCAGCTGGACCTCGACGAGTGCCAGAGCCAGCCGTGCGCACATGGGGGCACGTGCCACGACCTGGTCAACGG
Seq A exon
GTGAGCGAGCGGCGGGGCAGGCGGCAGGGGCGCCGGGTGCCCGAGGGCGGGGAGGCCAGGCGCGGGGCAGAAGGGGCAGGCGCGCGCTCAGCTCCGCCGGTGCGCCCTCCCCAG
Seq C2 exon
GTTCCGGTGCGACTGCGCGGGCACCGGCTACGAGGGCACGCACTGCGAGCGGGAGGTGCTGGAGTGCGCATCGGCGCCCTGCGAGCACAACGCGTCCTGCCTCGAGGGCCTCGGGAGCTTCCGCTGCCTCTGTTGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000148204:ENST00000373631:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(6.5=3.0),PF0000822=EGF=WD(100=47.0),PF0000822=EGF=PU(53.1=25.8)
A:
NA
C2:
PF0000822=EGF=PD(43.8=29.2),PF0000822=EGF=PU(80.6=52.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCCTTCCGCTGTGTGTGC
R:
CCAACAGAGGCAGCGGAAG
Band lengths:
253-367
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development