HsaINT0043087 @ hg38
Intron Retention
Gene
ENSG00000100448 | CTSG
Description
cathepsin G [Source:HGNC Symbol;Acc:HGNC:2532]
Coordinates
chr14:24574675-24575412:-
Coord C1 exon
chr14:24575265-24575412
Coord A exon
chr14:24574811-24575264
Coord C2 exon
chr14:24574675-24574810
Length
454 bp
Sequences
Splice sites
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
3' ss Seq
CCTACCTCTTGCTTTTGCAGCAA
3' ss Score
10.5
Exon sequences
Seq C1 exon
GGGAGATCATCGGAGGCCGGGAGAGCAGGCCCCACTCCCGCCCCTACATGGCGTATCTTCAGATCCAGAGTCCAGCAGGTCAGAGCAGATGTGGAGGGTTCCTGGTGCGAGAAGACTTTGTGCTGACAGCAGCTCATTGCTGGGGAAG
Seq A exon
GTGAGGAGCTAAGGAACTTCCTGGCCAGCCAGGAACACAGCCCTGCGGAGCTCTTCGGTGGAAGAGCCATCTGAAAGAAGAGTTGTAGCAATGAAAGGGTGAAAGAAAGACCAAGTGAGTCTTTGCGGGAGGGAACAGGCCAGTGTAAATGAGGAGGAAAGGAGGATAAGATCAAAAAGAGCAAGAGGAAGAGATGGAAGACACATATTGGGGCTCAAAATATAAACTCAGGCTATTTATCAACTTAATCTGGGGAAGCAAACCTGAAGGCAAGTACCACCCTGTCATCCCTAGCTCAGAGCTGCTGAGAAAGAGGATACAGCTGAGCCCCAGGGCCCTCCCATCCCCTCGATTCTGGTTAGCTGCAGTCTTGCCCTCCCCGTGCTGTCTGCCTACCCTGCAGAGCTGGTGGACCATAGCTCCTGCAGCCCAGACCTACCTCTTGCTTTTGCAG
Seq C2 exon
CAATATAAATGTCACCCTGGGCGCCCACAATATCCAGAGACGGGAAAACACCCAGCAACACATCACTGCGCGCAGAGCCATCCGCCACCCTCAATATAATCAGCGGACCATCCAGAATGACATCATGTTATTGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100448:ENST00000216336:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.240 A=NA C2=0.435
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=PU(21.6=94.0)
A:
NA
C2:
PF0008921=Trypsin=FE(20.6=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGAGATCATCGGAGGCC
R:
TAACATGATGTCATTCTGGATGGTCC
Band lengths:
278-732
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development