HsaINT0043552 @ hg19
Intron Retention
Gene
ENSG00000138161 | CUZD1
Description
CUB and zona pellucida-like domains 1 [Source:HGNC Symbol;Acc:17937]
Coordinates
chr10:124600694-124605691:-
Coord C1 exon
chr10:124605278-124605691
Coord A exon
chr10:124600845-124605277
Coord C2 exon
chr10:124600694-124600844
Length
4433 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
CCATCTGTGATCTCTAACAGGCA
3' ss Score
9.2
Exon sequences
Seq C1 exon
GAGGCCACCTGTTTGTGATGTGCAGGCACAGAAGAAAGGCACAGCTCCCCATCAGTTTCATGGAAAATAACTCAGTGCCTGCTGGGAACCAGCTGCTGGAGATCCCTACAGAGAGCTTCCACTGGGGGCAACCCTTCCAGGAAGGAGTTGGGGAGAGAGAACCCTCACTGTGGGGAATGCTGATAAACCAGTCACACAGCTGCTCTATTCTCACACAAATCTACCCCTTGCGTGGCTGGAACTGACGTTTCCCTGGAGGTGTCCAGAAAGCTGATGTAACACAGAGCCTATAAAAGCTGTCGGTCCTTAAGGCTGCCCAGCGCCTTGCCAAAATGGAGCTTGTAAGAAGGCTCATGCCATTGACCCTCTTAATTCTCTCCTGTTTGGCGGAGCTGACAATGGCGGAGGCTGAAG
Seq A exon
GTAAGAAAATTGAACCAGATTTATTCACCAAAACAGAGAAGTTCTTCTCTTAAGAGGCCTCTTTCAAAATTTTTCAAAGTGTTTATATCTGTTGGCCCCAGTTCAGAGAAAAATGTACTCTAATGCTCTTGGAGGGGATTTTAAATTAGTTCTAATTTTATTTGGCTCATCTGACAATGTCCATAAAAATATCAAAAGTGTATAGAATTTTACTGAGTAATTTACTGCTAAGAGTTTATGTTTTGGAAATAAGCATAAAAGTGTCCAAAGATATATGTATAAATATGTGCACTTACATAATTGTAAACTACAACATGAATTTTCATTATTTCTTACGGTAAATCCATAAAATGGAACACTCTTTTTTGCAACTTAAAAAAAAATGATGGCTGGGGGCGGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGCCAAGGTGGGTGGATCACGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAATTAGCCAGGTGTGGTGATGCGTGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATCGCTTGAACCCGAGAGGTGGAGGTTGCAGTTAGCTGCGATCATGCCACTGCACTCCAGCCTGGGTGACAGAGCAAGACTCCGTCTCATAAAAAAAAAAAAAAAAGACTCTGATCTATAATGTGTCCATAGACCACATTAAGAGAAAAAAGAGATCTGAAGTTTGTGTACAATATGATGGTTCTTATGTTTGAAATATATACATTCAAGCATTTTAAATGTCTAGAAATAGAAGAGGAAAGGAAAAGGAGTGGAAGAATTTACACCAAGGTTTTAGTGATGATTGTTTCTGGATGGATGGGGTTATGGGAGTATATGGGAGAATAAATAAAAATAAAGCTTTGTTCCTATGTAGGTGGGGTTTTTGACCATTAGTCAAAATCTTGGTGGGATTTTGAATTAGTACTAATTTTATTTGGGCCCATCTGACAACATACATAAAAATATAAGAATTTACCAAATAATTTTTAAAAATTTTATAGAAAAAAATTTTCACTATGTTGCCCAGGCTGGTCTCGAACTCCTGAGCTCAAGTGATCCACCCGCTTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGTCACCACGCCCAGCCCCTTACCGGGTAATTTCACTGCTAACAGCTTATCTTTAGGATCCAGTTATTTTTCCTCTTCCCCTTTTCTCTTTCTTCTCTTCTTTCTCCTTTTTAATAACAGCTTTATTAAGATATGATTAACATACCATAAAATCCACCATTTTAAAGTATACAATTTAGTGTTTTTTAGTATATACACAGAATTGTGCAACAATCACCACTATCTAATTCCAGAACATATTCTTCACCCCCAAAAGAAACTGTCTCAGGCTCAGCATGATGGCTCAAGCCTACAATCCCAGCACTTTGGGGGGCTGACATGGGAGCATTGCTTGAGGCTGAGAGTTTGAGACCACCCTGAACGACGTAGTGAGACCTCGACTCTACAAAATTAAAAAAAAAATTTTTTTAGCCAGGCATGGTGGTACATGACTGTAGTCCCAGCTACTCTGGCGGCTGAGGTGGGAGGATCACTTGAGCCCAGTAGTTTGAGGCTGCAGTAAGCTATGATTGTGCCATCTCAATCCAGTATAGGTAACAGAGTGAGACTCTGTCTGTCCCTCTCTCTATATATATATATATTTATATATAGTCTCTCTATATATATAGTCTCTCTATAGTCTATATATAGTCTTTATATAGTCTATATATATAGTCTCTATATATAGACCAATGTTTTATATATATATAAATATATCTAACAATATATATAACTGTATATTATATATAGACTAATGTGATGAATATTAGTGTACAAGTTTCTGTGTGGACATATATATATATATATATATATGTATGTATATATATGTATGAAGAAAGTCTGTATTCACTACCATTCACTCTCCATTTCTCCTGATGTCTCCAGCACAAGGAAACCACTACTCTACTTTCTGTCTCTATAAATTTACTTATTCTGGATATTTCACATAAATGAAATCATGTAATATGTGGTATTTCACTTAGCATAATATTTTCAAGGTTCGTATGTATTGTAGCATGTATCAGTACAATCAGCCCTCAGTACCTGTGGGTTCAGCATTCATGGATTCAACCAACCATGAATTGAAAACATTTGAAAAAATAAGGGTTGGTTACAGAACATGTACAAACTTTTTTCCTTGCTGTTATTTCCTAAATAATATAGTAAACAACTATTTACACATCATTTACACTGTATTATAAATAATCTAGAGATGTTTTGAAGTGTACAGGATGTGTGTAGGTCACATGCAAACACTGTCATTTTACATAAGGGACTCCAACATCCATGGATTTTGGTATCCACAGGGGGTCCTGGAACCAATCATTCGTGGACACCAAGGGATGACTGTACCTCATTTCTTTTTATTGCTGAATAATATTCCAATGTATGGATAGACCATGTTTTATTTATTCATCAATTGATGAACATTTGGCTTATTATGACTAATGTTGCGATGAATATAGTATACAAGTTTTTATGTGGACATTTGTTTTTATTTCTTTTGGGGATATGCCTAGCAATAGAATTGCTGGGTTATGATAACTGTATGTTTACTCTTTTGAGGAACTGCCAGACTGTTTTCCATGGCAGCTGTACCACTTTACAATCCCATAAGCAGTGTATAAGCATTCCAGTTTCTCCATGTCCTTGTCAACACTTGCTGTTTTCTGTGTTTGACTCTAGCCATCCTAATGCATGTGAAGTGATATCTCGTTGTGGTTTTCATTTGTATTTCCCTGATGACTAATGATGCTGAATATATCTTTACATGCATATTGGCCATTTATAGATCTTCTTTGGAAAAATGTCTATTCTGGTTCTTTGTCCATTTTAAATTGGATTATTTGCCTTTTAGTTATTGAATTGTAAGAATTCTTTATACATTCTAGAAATCAAGTGTCTTTTAAAAACCATCCTTTTTTTCCCAGGTTGATCTATAAATTCAGTGCAATTCCAATACAAATCCCAGTAAGAATGTTAAATAGATACAGACATGCTGACTCTAAAATTTATTGAAAAAGCAAAGGAACTGGAATAGCCAAAAAAATTTTGCAAAAGAACAGTAAAGTTGGAACAGTCATGTTACCTACAGTAATAACATAAACTACAGTAATCAAGCAGGTGTGGTTTGCCAAAAGGATAGACAGAGAAAATTGAAATAGAATAGAGTTCAGAAATAGATCCACACAAATATGGTCCTTTGATTTTTGACAAAGGTGCAAAGGCAATTTAATGGAGAAAGGACAGCCTTTTCATCAAATGGTCTTGGAACAATTGGACACCCATATGCAAAAAATGAACTCAACCTAAGCCTCATTTCTTACACATAAATTAGTTCAAAATGGATCATAGATCTAAATGTAAAATGTAAAACTATAGTATTTTTAAAAAGAAAACATGGGAGAAATCTTTGTAACCTGGGGTTGAGCAAAGAGTTCTTAGACAAGACACCAAAAGCACAACCCATAAAAGAAACTATTACTAAATTGGACTTTATAAAAGATTTAAAACTTTTGTTTTGGGAAAGACACTGTTAAGAGGATGAAAAGACAAGATACAGATTGGGAGAAAATATTTTCAAATTGCAGATGCAACAAAGGACTTGTATTCAGCATATATAAAAAACTCTCAAAACCCAATCATGAAAACAAAAAGCCAAGTTAAAAAAAAAAGGGCAAAAGACTGAGAGATACTTACCAAAAAGGATATATAGAAGGCAAATAAGAACATGAAATGATGTTCAATGTCATTAGCCATTAGGGAAATGTAAGTTAAAACCATGATGGGATGCTGCTACACATCTGTTAGAATGGCTATACAAAGCAATACAAAAACCTGACAATAGTGTGTGTTGACAAGAATGTGGTGCAACTGGAACTCTCATACATCATTGGTTGGATTGTGAAATAGAACAGCTACTCTGGCAAATGGTTTGGCAGTTTCTTATGCAGTTAAATATACACTTAACATATGACCTGGTGATATCACTCCTAGGTATTTATGCTAGAGAAATAAAGACACATGTTCATATGGAAACCTATTAAAAATACAAACCATCCTTCTTCGGGTCCTAATATAGTCTCTATATGTAGAGAAGTTAAAAATACTTCTCCTCAAAGGGTTCAAGACGGAGAAATCAACTGCTTTTGACTTACTTTGGAGAAAGCTAAGTACCATCCACAATTAGCTGCCTACTTGTATGTATATTACATGTGAGAGGTAGATTCCTAATCTCTCAGGGAGGGGAAAGGGCCTGTTGACTTTCCTGAGTGCCATCTGTGATCTCTAACAG
Seq C2 exon
GCAATGCAAGCTGCACAGTCAGTCTAGGGGGTGCCAATATGGCAGAGACCCACAAAGCCATGATCCTGCAACTCAATCCCAGTGAGAACTGCACCTGGACAATAGAAAGACCAGAAAACAAAAGCATCAGAATTATCTTTTCCTATGTCCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138161-CUZD1:NM_022034:1
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0043115=CUB=PU(29.8=54.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)