HsaINT0043553 @ hg19
Intron Retention
Gene
ENSG00000138161 | CUZD1
Description
CUB and zona pellucida-like domains 1 [Source:HGNC Symbol;Acc:17937]
Coordinates
chr10:124598533-124600844:-
Coord C1 exon
chr10:124600694-124600844
Coord A exon
chr10:124598748-124600693
Coord C2 exon
chr10:124598533-124598747
Length
1946 bp
Sequences
Splice sites
5' ss Seq
CCAGTAAGT
5' ss Score
9.09
3' ss Seq
CAGTTGTGTTTTTTCCACAGGCT
3' ss Score
9.6
Exon sequences
Seq C1 exon
GCAATGCAAGCTGCACAGTCAGTCTAGGGGGTGCCAATATGGCAGAGACCCACAAAGCCATGATCCTGCAACTCAATCCCAGTGAGAACTGCACCTGGACAATAGAAAGACCAGAAAACAAAAGCATCAGAATTATCTTTTCCTATGTCCA
Seq A exon
GTAAGTAGAAGCTTTAGTTTCCTAATAAGGGATATCGAACTCTGACCACATTGGGGTGGGTAGGGGGACTCTCTGTAGAAAGAATTCAGCTGCTGCTAGAGGTGGTAGTGACACTGACAACCATCGTGATGATGATGGTGATGAGGATGATGGCTGATAGTCACTGATGATGGCTGTGTGCCCGGCACTGGCTCACAGAGGTCCTTCAAGGTCAGCACTATAATAGTACTACAAACACAACAAGGTTGAGAACTTGTCTGAGGTCACACAAATAGTGAATAGCATGACCAGAGTTAGAACCTAGCTGGTCTAGTTCCAGTTTCTTGGCCTTAAAACACTAAACTTTGGTTCCAAATTTTTCTATGCATTTGAATCAGTGGAGGAGCTTTCACACATCCAGACTCCCAGGCTGTACACCATATGATTAGATTATAATCTCTGGGGGTAGACTCCAGGCATCAATATTTTTTATTTTATAGATTTTATTTTGAAATAAGTATACATTTATAAGTGCTTTTTATAAGTGCCCAGGTGACCCCAGTGTGAGGCCAAGCTGAGAACATGACTCCGCCCTGCAGAGACGCTCAGTGTTTCCTATCTGCCTCTAGTTAATCCTCTCAACAACGCTCTGGGCAGATGCAGTCTAATCCCCATTCTATAGATAAGAAAACACAGAGAAGTCACCAGGTCCAAGACTAAAAAATAATAAAAATGGGATAGGAACTGAATCCAAGCAGCCTGGCTCCAGAGCCCCCCTCTTACGCCTGTCCCAGTGGTTCTTACACTTGACCATACATCAGAAGCCTGTGGCAAGCTTATTAAAACACAACTGCTGGGCCCCACCACCAAAGTCTCTATTGTCTTATTCAAATGGAGTGTGTGGGACCTGAGAATCTGCATAGCTAACAAATGCCCAGGTGATGTTGATGCTGCAGGTCCAAGTACCACACTTTTGAGAACCATAGCCCTGTACCACTGAAGTTGGAATTTACTTTATCCTTCAAAGAAGCAAAAGAGGCCTCAAATTTCCTGGAATGGTTGCTGAGAAACATATATGCTATTCTTGCTGTGTAAGAAGAGAGGGGAAGAGAAATTGTGGGAAGAGCAAGGGAGGCGAGAAATTAACATTTAACATCTATTGAACACCTATGTGCCAGGCCTGTGGCAGGTGCTTCATATTCAGAATATTATAAACTTCACACAGTAATGAGAAGTAGGCTGTGATATCCCCATTTTACAGATGAGAAAACTGAAGCCAAGAAAGGTTAAATCACTTATCTAAAGTTATACAGCAGGTAAGTGACTAAAGTGGAAAGAGAACCCAGATTTCTCTACCCTTGTCTTACTTCCTATAATTTTGGACATATGTCCTCTGAGGATATTTGGAGAGACCCTGTCAGAATGTGCAGCAAACTACAACCCTGGGCTGTCCTGTCCAGTGCAGGGCATGGGACTGTCCTTCAGAATGAGGAAGTGGTGATACAAGGGAAGGAAGGAGCAACTAGGGAGGTGCTAAGGTTTGCTTTTCCTTGGGAAAGGTGGCTATGGAAGAAGAAGAGTTGCTTCACCTTTCAACAGCCTTGGATATCAAGTGTCAATGGGAAACAATTCTAAATAAGAAGGTTCATCAAAGAGTTACATGGACATGGGGAACAGGAGAGATGGAAACAGGTAGAAGGAAAGGAATTCTGATTCCAGGCGCATCCTCATCATTTACTTGATACAAGACATAGGCAAAGCAGTTCATCTCCCTGAGCCCATTAAAGTTGACAGTTTGTGGTTTGATGTTGAGGATGGTGGGGTTGGTGATTGGTCTTGGAGAGGTTTAAATGAAAACAGATGTGCCACCACTTTGTAAATTTACATGCCTAGGTGAGCAATTGACTGCTCTGCAAACCCCCTTTGCTTGTGACACTTCTTCAGCCACAGTTGTGTTTTTTCCACAG
Seq C2 exon
GCTTGATCCAGATGGAAGCTGTGAAAGTGAAAACATTAAAGTCTTTGACGGAACCTCCAGCAATGGGCCTCTGCTAGGGCAAGTCTGCAGTAAAAACGACTATGTTCCTGTATTTGAATCATCATCCAGTACATTGACGTTTCAAATAGTTACTGACTCAGCAAGAATTCAAAGAACTGTCTTTGTCTTCTACTACTTCTTCTCTCCTAACATCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138161-CUZD1:NM_022034:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043115=CUB=PU(29.8=54.9)
A:
NA
C2:
PF0043115=CUB=PD(69.1=89.0)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCAAGCTGCACAGTCAGTCTA
R:
AGGAGAGAAGAAGTAGTAGAAGACA
Band lengths:
354-2300
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)