HsaINT0044229 @ hg19
Intron Retention
Gene
ENSG00000197408 | CYP2B6
Description
cytochrome P450, family 2, subfamily B, polypeptide 6 [Source:HGNC Symbol;Acc:2615]
Coordinates
chr19:41509906-41510351:+
Coord C1 exon
chr19:41509906-41510068
Coord A exon
chr19:41510069-41510201
Coord C2 exon
chr19:41510202-41510351
Length
133 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGA
5' ss Score
7.23
3' ss Seq
ACACCTCCCCTGCACCCCAGGTG
3' ss Score
8.24
Exon sequences
Seq C1 exon
TTCCGAGAGAAATATGGGGACGTCTTCACGGTACACCTGGGACCGAGGCCCGTGGTCATGCTGTGTGGAGTAGAGGCCATACGGGAGGCCCTTGTGGACAAGGCTGAGGCCTTCTCTGGCCGGGGAAAAATCGCCATGGTCGACCCATTCTTCCGGGGATATG
Seq A exon
GTGAGAGCCTCAGAGGCACTGGGAGGGGGCGGGTGGGGGGTGCATCAGGGAAGGGAGTATATGGGAGGAAGAAGGACTCAGAGCCTTCTTCCAACTTCTTCTACAACCAACCCACACCTCCCCTGCACCCCAG
Seq C2 exon
GTGTGATCTTTGCCAATGGAAACCGCTGGAAGGTGCTTCGGCGATTCTCTGTGACCACTATGAGGGACTTCGGGATGGGAAAGCGGAGTGTGGAGGAGCGGATTCAGGAGGAGGCTCAGTGTCTGATAGAGGAGCTTCGGAAATCCAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197408-CYP2B6:NM_000767:2
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(11.8=100)
A:
NA
C2:
PF0006717=p450=FE(45.0=100),PF0006717=p450=PU(1.8=5.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGGAGTAGAGGCCATACGG
R:
CCTTGGATTTCCGAAGCTCCT
Band lengths:
250-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)