HsaINT0044229 @ hg38
Intron Retention
Gene
ENSG00000197408 | CYP2B6
Description
cytochrome P450 family 2 subfamily B member 6 [Source:HGNC Symbol;Acc:HGNC:2615]
Coordinates
chr19:41004001-41004446:+
Coord C1 exon
chr19:41004001-41004163
Coord A exon
chr19:41004164-41004296
Coord C2 exon
chr19:41004297-41004446
Length
133 bp
Sequences
Splice sites
5' ss Seq
ATGGTGAGA
5' ss Score
7.23
3' ss Seq
ACACCTCCCCTGCACCCCAGGTG
3' ss Score
8.24
Exon sequences
Seq C1 exon
TTCCGAGAGAAATATGGGGACGTCTTCACGGTACACCTGGGACCGAGGCCCGTGGTCATGCTGTGTGGAGTAGAGGCCATACGGGAGGCCCTTGTGGACAAGGCTGAGGCCTTCTCTGGCCGGGGAAAAATCGCCATGGTCGACCCATTCTTCCGGGGATATG
Seq A exon
GTGAGAGCCTCAGAGGCACTGGGAGGGGGCGGGTGGGGGGTGCATCAGGGAAGGGAGTATATGGGAGGAAGAAGGACTCAGAGCCTTCTTCCAACTTCTTCTACAACCAACCCACACCTCCCCTGCACCCCAG
Seq C2 exon
GTGTGATCTTTGCCAATGGAAACCGCTGGAAGGTGCTTCGGCGATTCTCTGTGACCACTATGAGGGACTTCGGGATGGGAAAGCGGAGTGTGGAGGAGCGGATTCAGGAGGAGGCTCAGTGTCTGATAGAGGAGCTTCGGAAATCCAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197408:ENST00000324071:2
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(11.8=100)
A:
NA
C2:
PF0006717=p450=FE(57.5=100),PF0006717=p450=PU(1.2=3.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGGAGTAGAGGCCATACGG
R:
CCTTGGATTTCCGAAGCTCCT
Band lengths:
250-383
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development