HsaINT0044256 @ hg38
Intron Retention
Gene
ENSG00000165841 | CYP2C19
Description
cytochrome P450 family 2 subfamily C member 19 [Source:HGNC Symbol;Acc:HGNC:2621]
Coordinates
chr10:94780499-94781997:+
Coord C1 exon
chr10:94780499-94780659
Coord A exon
chr10:94780660-94781820
Coord C2 exon
chr10:94781821-94781997
Length
1161 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
AAATTATTGTTTTCTCTTAGATA
3' ss Score
7.82
Exon sequences
Seq C1 exon
CTTCACCCTGTGATCCCACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGCTCCATTATTTTCCAGAAACGTTTCGATTATAAAGATCAGCAATTTCTTAACTTGATGGAAAAATTGAATGAAAACATCAGGATTGTAAGCACCCCCTGGATCCAG
Seq A exon
GTAAGGCCAAGTTTTTTGCTTCCTGAGAAACCACTTACAGTCTTTTTTTCTGGGAAATCCAAAATTCTATATTGACCAAGCCCTGAAGTACATTTTTGAATACTACAGTCTTGCCTAGACAGCCATGGGGTGAATATCTGGAAAAGATGGCAAAGTTCTTTATTTTATGCACAGGAAATGAATATCCCAATATAGATCAGGCTTCTAAGCCCATTAGCTCCCTGATCAGTGTTTTTTCCACTAAACTCCAAAGCCCTGTTTCTATAAAGTACTTTGGTGACAGCCCCAAAGCGTGCTTATATCACTCCATGGACATCCAGGCACTTTGGAGTCTTCCATTACTCACAAGGCTTGTCCTTCAATTCACACTTTGTCATATTGTGTGACAGAAATATCCTAATCTAAAAGACATTATCTCCTTCAAGGACAGAGAATATTTGGAACCACAGAAGCTGCCAAGAAACACTGAATAGGGCAGAGGTGTTTGATGTCTCAGTTGGGATTCTAGCTGATGAGACAGCTGGTTAGGAATGAAAAAATTATTGTTTTTTTGGTGTATGAACCATAAACAGACATCACACTTTTACCCTGTGCTGAATTGGCATGTTTTATACTCTGCCTAAATAATAATTGTATGATTTTACAGAAGTCATTTAACTGCTCTGGTGCACAGTTGGAATTTGAAGTATCTTTGAGCCCCTCCCACTTCTAAAATACTAATTCAATTTCAGAGGCTGCTTGATAGAAATCAATATAGCAGGGACTATCTTTGTAGTATCAATCAGGTTGTGCAAACTCTTTTAACCTATGCTATCATCTCCAAAATGTTAATGTAGTAATTCATACCATCTTATATTTCAAGATTGTAGAGAAGAATTGTTGTAAAAAGTAAGAGAATTAATATAAAGATGCTTTTATACTATCAAAAGCAGGTATAAGTCTAGGAAATGATTATCATCTTTGATTCTCTTGTCAGAATTTTCTTTCTCAAATCTTGTATAATCAGAGAATTACTACACATGTACAATAAAAATTTCCCCATCAAGATATACAATATATTTTATTTATATTTATAGTTTTAAATTACAACCAGAGCTTGGCATATTGTATCTATACCTTTATTAAATGCTTTTAATTTAATAAATTATTGTTTTCTCTTAG
Seq C2 exon
ATATGCAATAATTTTCCCACTATCATTGATTATTTCCCGGGAACCCATAACAAATTACTTAAAAACCTTGCTTTTATGGAAAGTGATATTTTGGAGAAAGTAAAAGAACACCAAGAATCGATGGACATCAACAACCCTCGGGACTTTATTGATTGCTTCCTGATCAAAATGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165841:ENST00000371321:4
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.034
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(11.6=100)
A:
NA
C2:
PF0006717=p450=FE(12.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCACCCTGTGATCCCACTTTCA
R:
TCTCCATTTTGATCAGGAAGCA
Band lengths:
334-1495
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development