HsaINT0044256 @ hg19
Intron Retention
Gene
ENSG00000165841 | CYP2C19
Description
cytochrome P450, family 2, subfamily C, polypeptide 19 [Source:HGNC Symbol;Acc:2621]
Coordinates
chr10:96540256-96541754:+
Coord C1 exon
chr10:96540256-96540416
Coord A exon
chr10:96540417-96541577
Coord C2 exon
chr10:96541578-96541754
Length
1161 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
3' ss Seq
AAATTATTGTTTTCTCTTAGATA
3' ss Score
7.82
Exon sequences
Seq C1 exon
CTTCACCCTGTGATCCCACTTTCATCCTGGGCTGTGCTCCCTGCAATGTGATCTGCTCCATTATTTTCCAGAAACGTTTCGATTATAAAGATCAGCAATTTCTTAACTTGATGGAAAAATTGAATGAAAACATCAGGATTGTAAGCACCCCCTGGATCCAG
Seq A exon
GTAAGGCCAAGTTTTTTGCTTCCTGAGAAACCACTTACAGTCTTTTTTTCTGGGAAATCCAAAATTCTATATTGACCAAGCCCTGAAGTACATTTTTGAATACTACAGTCTTGCCTAGACAGCCATGGGGTGAATATCTGGAAAAGATGGCAAAGTTCTTTATTTTATGCACAGGAAATGAATATCCCAATATAGATCAGGCTTCTAAGCCCATTAGCTCCCTGATCAGTGTTTTTTCCACTAAACTCCAAAGCCCTGTTTCTATAAAGTACTTTGGTGACAGCCCCAAAGCGTGCTTATATCACTCCATGGACATCCAGGCACTTTGGAGTCTTCCATTACTCACAAGGCTTGTCCTTCAATTCACACTTTGTCATATTGTGTGACAGAAATATCCTAATCTAAAAGACATTATCTCCTTCAAGGACAGAGAATATTTGGAACCACAGAAGCTGCCAAGAAACACTGAATAGGGCAGAGGTGTTTGATGTCTCAGTTGGGATTCTAGCTGATGAGACAGCTGGTTAGGAATGAAAAAATTATTGTTTTTTTGGTGTATGAACCATAAACAGACATCACACTTTTACCCTGTGCTGAATTGGCATGTTTTATACTCTGCCTAAATAATAATTGTATGATTTTACAGAAGTCATTTAACTGCTCTGGTGCACAGTTGGAATTTGAAGTATCTTTGAGCCCCTCCCACTTCTAAAATACTAATTCAATTTCAGAGGCTGCTTGATAGAAATCAATATAGCAGGGACTATCTTTGTAGTATCAATCAGGTTGTGCAAACTCTTTTAACCTATGCTATCATCTCCAAAATGTTAATGTAGTAATTCATACCATCTTATATTTCAAGATTGTAGAGAAGAATTGTTGTAAAAAGTAAGAGAATTAATATAAAGATGCTTTTATACTATCAAAAGCAGGTATAAGTCTAGGAAATGATTATCATCTTTGATTCTCTTGTCAGAATTTTCTTTCTCAAATCTTGTATAATCAGAGAATTACTACACATGTACAATAAAAATTTCCCCATCAAGATATACAATATATTTTATTTATATTTATAGTTTTAAATTACAACCAGAGCTTGGCATATTGTATCTATACCTTTATTAAATGCTTTTAATTTAATAAATTATTGTTTTCTCTTAG
Seq C2 exon
ATATGCAATAATTTTCCCACTATCATTGATTATTTCCCGGGAACCCATAACAAATTACTTAAAAACCTTGCTTTTATGGAAAGTGATATTTTGGAGAAAGTAAAAGAACACCAAGAATCGATGGACATCAACAACCCTCGGGACTTTATTGATTGCTTCCTGATCAAAATGGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000165841-CYP2C19:NM_000769:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.034
Domain overlap (PFAM):
C1:
PF0006717=p450=FE(11.6=100)
A:
NA
C2:
PF0006717=p450=FE(12.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCACCCTGTGATCCCACTTTCA
R:
TCTCCATTTTGATCAGGAAGCA
Band lengths:
334-1495
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)