HsaINT0046771 @ hg38
Intron Retention
Gene
ENSG00000162777 | DENND2D
Description
DENN domain containing 2D [Source:HGNC Symbol;Acc:HGNC:26192]
Coordinates
chr1:111199623-111204409:-
Coord C1 exon
chr1:111204296-111204409
Coord A exon
chr1:111199799-111204295
Coord C2 exon
chr1:111199623-111199798
Length
4497 bp
Sequences
Splice sites
5' ss Seq
GGGGTTAGT
5' ss Score
2.75
3' ss Seq
GGGCTCTGGCTTGATTTCAGGAC
3' ss Score
5.88
Exon sequences
Seq C1 exon
ATAGGGGGGCGGGGCCAGCGCGGAGCTGGGAGCGGGAGCCGGGCACTCCAGGGGCCATGGATGGGCTCGGCCGCCGCCTTCGAGCCAGCCTGAGACTGAAGCGCGGCCATGGGG
Seq A exon
GTTAGTGCCGGCCGGGGAGAGCGCGGGGGGACGGCGTGGGCACCGGGGAGCCGGGGCTAGGGCTGGCGGCTGGGGCCCGGTGGAGGGCGGCACGGGGCGTCGAGATCCGGGAGCAGTTGGAAGGGGACTCAGGAGGCTGCGCGGGGGCAGGTGAGCGGGAAGGAGCGCGCGGAGAGGGGAAGAGGGTCAGGTGGGGGCGGGGACGGCGAGGCCAGGCCTGAGGGGGCGAGGGGGAGGCGGCGGGACACAGGAAGCCGTTGTGGGGCCCCGGGGCCACGTGTCCTTCCATCCAGGAAGCTTGTGGTGCAACCGCAGTGTGCCTGAAAGCGCCCCGGTTGTGGTGTCCTCCCAGAGGCACTGCCTCAGCTCCCGGCGTGCCCGCCGCCCCGCCCCACCTCGCCGCCCTGGGAGTCCTCCGTGGTCTTTGCCCAGTTCCTCGGAGCCAGCGCCCCTGCCCCTGCCCAGCAGATAGCCACCGGCCACAAACACAGGTCTCCCCGATGACGTTACCACCCCCACCCACCCTCGGCCAGGTGCCCTTCAGAGTGTGGCCTCCAGCGGAGCGGCGGTAGAACCTGCGCAGCTGCTGCTTTCCAGCGTGTCGCCCAGACAGGGCACCCCTTCCCTTTCCCTCAGCCCCGCAACAGTGAAATGGACATAATTCCCCCGTCCAGGATTATGGGGATTAAATTAGAAGTCAACTTCTAAGTTAAAGAAGCACCTTCTTTTCTTTCTTAGCAGAGCCCTGGGGTTGGAAGGAGGGCAGTTAGAAATTCATTCATTTATTCATTCACTCGGCAAATATTTGTGTGGCTTACCACTAGCCAGTCCTATGGCTGAACAGCCGTGACCCTTAGATACTTTGCCCAGAGGTCCTACTGTCTGAGGAGCAAAGAGCAGGGGCCATTCCCAGACAACCTGCCCTTTCCAACATTGGCACGCCAGGAGGCCAAGTGAGCCCCTCTCTTAGCCCAAGCCCCAGAGTTGGGGGGACCTCAGGGAGTGAGGTCAGTGCACCCTTCTTTGAACTGCAGTGACCTCTGAGTGATCTGCTCTTCCTCCTGTTGCCATTCCTCCTGCCACACCCTGCTCCTTCCCTCTTTGTAGTGTCCTCTCTAGACACAGATCTCCAATATCTGGCCATTCCATCTGCACCATCAGGGAGAGGTCAGAGACCACAGTTTGGGGCAGAGGCCTGGGACCGTGCAGTGGTGGGAGCAGAAGGCAGGATGAGGCTGACATTCTCTCTTCTCTGGAGAGCACTGGCCTGGTCTGTCCTGGTCTTCCCAGACCCTGGGACATCTGTGTGAATGGAAGGGGTCTGCCCCCTGCAGCCCAGAGGAGACATTCCAGTTGTTCCCACCCACCCCTGCCCCAACACCAGGCACTTCCTGATTGTGCCTGGAGGAGCTTCCTGATACTGAGGAACTGTAAGAACTGAGGCCTAACACTTGTAGGGCCAGGAGCATATGCCCTCTTCATCTTCCATACCATCCTCCACTTGCCTGGGGATTCTCCCCCTTCCTCCTTTGCCTTTCTGGCCCCAGGACAGTTGTGTATTAGGAGGGAGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTATCCTGGTGACAAGGAGTGATGTGGTGGTGGTCCTGGGTTGAGAGCAGCTGAGCTGGAAGGGATGGGCCAGCTTCCCAGATCAAGGTTCCAGAAGGTCCCCTCACCTATGTTCTAGACAGATCTGGGACTTCAGTCAGGTGTGTGTGGGAGAGGCTTTCTGGTGGAGGAACAAGTGTAACCAGATTCCTGACTTCCCTAGAAAGGGTGGCTCCCTCCTCAACTAAAACTCTGAATAATAATTCCTTTCTAGGGCACTGGAGATTAAATGAGATGCCTTATATGAAACATGAGTTTGATGGAGGTTAGTTTTCTCTTACGCTTTTCTCTCCTGTGGATAACACCTTTTGAAAGAGGGGAGAAAACAGTCTTTTGCTGCATTTCTTGGGCCTCATCCCAAAAGTCTAATTACTTTCTTTTGTCAATGATTTATTAATTTTGCTATTCTCTTGGCTTGCTTGATAAAGCAGAAGAAAATGATCTGAAAACGCAGCCCAAAGGATTTAGGGAAAGGCATAATTTCATTAGAATCTGGAATGATCAGTGATAAGATTCTGTTTCTCAATGTCCTTTGAAAACCTCTGTGGGGTATTTGATGTCAAATGCATCCAGAAGGCAGGAGCATGGATTTGGAGCTTTCCTAATCCCCATTCCCAACAAATCCTGTCAATTTTAATAGCCTTTGAATTACTTTATGCCTCAGTTTCCCCATCTGTATCAGGAAGATGCTTGTTCCTCAAACAGGTGGTAAGGCTTGTGCAACAAGTCTGTGCAGCTTGCAAGTAAGGTGTGGTGCCAGCTCCAAGTGTTCTAGTTCGCTCTTCTCACCCATTACAGCATTTGAACATCTTTCTTTACTGTACATGAGTTTGGCCGTGAGTCCTGGCTTTTTCTAGTCCCACAGAAGCCAGGTCTAGAGCTCTTAGGAGCAAAGCAGCTGTTTTCCCTATCCTAGCACCCCACTCTCTTCCAGAGGGGTGCTTATTCTTAGCAGGAGTGGCAAACACTGGCGTCAAACCCTTTTGCCCCCTGCTTTCCCTTTGAGGCAGCTTCCTGGTAAAAGCCTTCCCTGTATTTACTCATTCAGGGGTTTCTGTGAGAATCCAAGGTGATTTTTTTGCTATTCCTTCTCTCTTACCTAGTCTCCAGACACAGCAGTGGGCTAGCAGCTGTGCCTGTAGCTTGGGCAGAACAGCTGACCTGGCCTGACCCGGAGGAAGGCTGAGCAGGCGTGGGGGTTGGGTGGAGATCACCCAGATGTTTTCCACTGCCATGGAATCACCCTCAGGCTGCTGGTGCAATCAGTCCCCTACCTTATGCTGGGGACAGTCTTCTGAGCCAGTGCTTCCTATTTGAGAAGAGGGACTCTGCTGGAACCCTGGAACAAGTGCCAGTGACAGAACTCTCCAGGGGGTGAAATTCACCATTGTAGCTATTTCCAAAATATCACGAACTCTGGGCTTAGAGATGGATTTTGCTCTCTACTGCACCATCAGGAAAGAAGGCTATTGGGTATTGACTTCCAGAACTCTTTCTTTTGTTGGAAGAATTAATCTATTTGGATAATTATTAGGCCAAGTCTATTTATCTTAATCAGGGGAGGGCAGTGACATCCTGGCTGCAGAAAGTGTTTGGCCATGTGCTCTAGGTCGGGAAGTCCTGGAAGTTCTAGAATTCAGCAGGTGGCCTTGCTGGGGTTTTTGACTTCCGTTGACCAAGTTGAGAAGTGAAAGGTCAGCAATCCAAGTGTTGGAGGTATAGGATCCCTATCCTGAGACCAGCCGGTTTCCAGTGCCCACAGTCTGACACTATCAAGCATTGTCCACTGTTCTAAGGTTGTAAATTAACTCTCTGCACAATCTGCAGCCCAGATTCAAAACCCTTAGCCCATAAGTAGCCAGGCCTTTCCGGCTACTTTCAGCCAGAGGTGTTTGCTCATGACCTTTTCTCTCGCCACACCCTGGGGCTCTTGGGAGGAGCTGAGATCTGCGCTGCAGTGCCAGGATGCTGACTCTGTTGGTGCTGGCTTCTGCTGCCTTCCTGGGTCCCGTCACATCCTTCTTGCTCAACCACTGGGTGCACAGGATGGAAACTTCTATTCCCTCTCTGGAAGACAGCGCGTGGCTTGGCTTCACAGAGTTGTGGCTGGAGACCGAAGCAGCCCCTTTCTCAGGCTTACTGTCACCAGTCTGTCTGTGTTAGGGGAGAGGGGAGTCCGCTCTGTCCTGAAGGCCCAGAGATGGAAGGACAAGTGGTAGGCCGGGTGTTCAGGCTCTTCCAACGCCGACTGCTTCAACTCCGAGCAGGTCAGGACTGGACTGCCTACTTCCTTGTTTTTAGGGTGACCCTCTTAGGCGGGACTGTTTCTTCCTTGAAATGCTCCTTCCTCCTCTTCCTTTATATCTCGGCCTCCACATGGTTCCCCATGTGACTGGGTCAGGAGGCTTCCTCTGCTGGTTTTTAAGAGCTGGTCATGCCCTCTCTGGGGCTAGTGTGGTCACAGTCACATGCCCTTTGAGCCTGTTCTTATTCACTTAGTATGAACTAAACTCTCAGGCCATATTGTTCCAGGACTGCCAGAAGCACCCGACAGGTTAGGCAGTCTCTGTGGTACCCTGGGGCCTTGGCCTCCATGTGGCCTCTCCAGCACATTTCCGTGGCTTCTGTGTCAGTGGTTTCTTTCCTCTGCTTGGCTCCCCATGGTTTCAAGTCTACCAGGGCAGGTGTGGAAACTGCCCATTTGGCCCTGATCCTGAGTGACTGGTGGTTCTGGCCAGTATCCAGGTATCTCAGCATTGGCAAGGCGGCCTTGAGGTGTGGAGGTCACCCGGATTCTCACAGACTCCACTCCAGGAATGGATCAATGAGATTATACTAAATGGGCTCTGGCTTGATTTCAG
Seq C2 exon
GACCACCCCAGGACAATTCAGGGGAAGCTTTAAAGGAACCAGAAAGGGCCCAGGAGCACTCTTTGCCCAACTTTGCTGGGGGGCAGCACTTCTTTGAATACCTTCTTGTGGTTTCTCTCAAAAAGAAGCGTTCAGAGGATGATTACGAGCCTATAATCACCTACCAATTTCCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000162777:ENST00000369752:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.225 A=NA C2=0.349
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0345613=uDENN=PU(12.7=15.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development