HsaINT0048736 @ hg19
Intron Retention
Gene
ENSG00000144355 | DLX1
Description
distal-less homeobox 1 [Source:HGNC Symbol;Acc:2914]
Coordinates
chr2:172951382-172954401:+
Coord C1 exon
chr2:172951382-172951581
Coord A exon
chr2:172951582-172952730
Coord C2 exon
chr2:172952731-172954401
Length
1149 bp
Sequences
Splice sites
5' ss Seq
CAGGTACCT
5' ss Score
8.16
3' ss Seq
GTTGTTGTCCGCTCTTGCAGGTC
3' ss Score
10.46
Exon sequences
Seq C1 exon
GGGCGGACTCGGAGAAGAGCACGGTGGTGGAAGGCGGTGAAGTGCGCTTCAATGGCAAGGGAAAAAAGATCCGTAAACCCAGGACGATTTATTCCAGTTTGCAGTTGCAGGCTTTGAACCGGAGGTTCCAGCAAACTCAGTACCTAGCTCTGCCGGAGAGGGCGGAGCTCGCGGCCTCTTTGGGACTCACACAGACTCAG
Seq A exon
GTACCTCGCCGCTGCCGCTCCGTTCTGCCACGCAGGCTTTCCGCGGCCGGCCTGCGCCCGGGTCTTCATTTGTTGCTCGCTGGGACTCAGGGTCGGGGTGTCACTGTGTGTATGTGTTTGTGTCCACCCCTGGCTCTCAGCGTGTCTCCTTCCTCCCTCATTCCCTCTGCCCTAGCTCTGTCACTGCTCTCGGTATCCCGAGCTGCCTGCCGTCCGGCCCTCTGTCCCTGGACAATCTGATTAGGGCGCAGGAAGGATTTCCCCAGACGATTTGTTTGGGAACTCAGAGGTCACACGTGCCTAAACAACTGGAACAATAGACTCCGGGCTTAATCCCTCCTTTGCCTTTAAATTGTGTGACTAATCACTCGGGGCCTGGGTCCGCGCCTCAGCCTCCCTCCTCCTCCTCCTTCTTACCGGTTGGGGGTGGGGGGAGATCCTTTCCTCCGCCCTCTCACCTCTCAAGTCCCAGACCTTAGAGAAGAAACGGGACCTTCCTTCCCGGCTTTCTGTAAGACTCCGGGGAGCCCGTGAGCGTTCCTGACGGCGGCGGGCGCGGGTTTCCGACGTCCGGTCCGGGATTTGGAGCAGAGCTGGAGAAAGCAAACAGACACTAGTGCAAGAATGGTTTTGAATCCAAAGAGAAGTTCAGCAAAACCTTGAGGCCTCCTTAGTCCGTCCCAACTCAAGGGCAGAAAAGATGGCGCATAGAAAAGTTGGGTCGCGTTGCAAATAAATTTCCTCCACTCCTTCCTAGGTTTTCGATTCTTTTTATTGATGTTGATATTGGAATTGCTGGCTCGGTGTTATGCAGGCGCTGTATCTTCCGCAGGCGGTAGCCACGGTCGGACTGAGCCCCTGGCAGGCTAAGGCCTGGATCCCGGTTCTCCCCTCATCACAACTCCTCCCTGGCTCTCTGAGAGCTGCCCCCGTGGGCTGACGGCGGCGGGAGGTTCGGCCTTCGAGCCTTTGGCTCTTATGGGGGAAGGGAGGAAGGAGGGATGTCTCTGCTTCTCTGGCAGGGAGCTGCCAGCTGGCGCAGGGTTGGGAGGTCCTATCTCTGCTGTTCTGCGGTCCCTTTTTTCCTCCCTGTGACCTAGGTAGGCTCAGTGGTCCCAGCCTGAGTCACGTTGTTGTCCGCTCTTGCAG
Seq C2 exon
GTCAAGATCTGGTTCCAAAACAAGCGATCCAAGTTCAAGAAGCTGATGAAGCAGGGTGGGGCGGCTCTGGAGGGTAGTGCGTTGGCCAACGGTCGGGCCCTGTCTGCTGGCTCCCCACCCGTGCCGCCCGGCTGGAACCCTAACTCTTCATCCGGGAAGGGCTCAGGAGGAAACGCGGGCTCCTATATCCCCAGCTACACATCGTGGTACCCTTCAGCGCACCAAGAAGCTATGCAGCAACCCCAACTTATGTGAGGTTGCCCGCCCGTCTCCTTCTTGTCTCCCCGGCCCAGGTCCCTCCCGCCTCCAGGTCCATCCATCCCGTCCGGAAAAGAAGGACCCAGAGGGAAGAAGGAACAGTGGAGGCGGGACGCCCTCCATCTCCTCGGAGCCCCGCGAGGTCCGGCCCAGCAACTTCCCGGCATCCGCGCTCTAGCCTGAACCCTGGCCTGGGCCGAGCAGTGGCAGCAGAGAGTGGCCTCGGAGGGAAGCCACTGCCACCTGAGACAGCCCAAGCAGCAAGATAAACCCGCTCCACCCGACCCGCCGACCTTCAGCTTTGTGGGACTATCAGGAAAAAACAAAACAAAAACAAAATGTAGAAAAAGCAAAAGCTCTTTTCTGTCCTGTCAGTCTCCTGTCTCCTTTTGCTCTGTCTGTGCGCTGGTAAAGTCCAGGTCCTCATCCGTCCGCTGTCCTCATTCTGCGGCCTCAGCAAAAAGCCACAAGGTCTGAGCGGCCCGGGTCCTGCCGGGCTGACCATCTCCGGATCCTGGGACACTCTGCCTGACCATCTGTGTAGCTGGTGTGGGAATCTGGGGGCATTGGAGGGAGGGGGTTTTATTTATTGAGAAATGGACTTCGCCTGAGGCTGTTTGCCAATTCAGGGTTCTGCTGGGCGCAAGGAACGCACTGTTCAAACGCACTGTTTACTTTAAGCGCACGGGGAGAAACGAATAAGGAGGACGTGGTGATTTTTAATTTATACAGTAACTTTTGTACTTCTCTGGTATGGAGAGTTTGGAGCCGAATGATTTGCATTTTTTACATGTCCGACATTATTTAATAAATAATTTTTAAAAGAAAAGAACGATAAATGAAGCCAACATGATTTTCTCATTTCGGGAGGAACTCTGTTGCTTCGCCTGGACAAGAAGGAAAATGCTGATTTCCTCCTTGGGTAGAAAGAGGGAGCGAGGGCAAATGGGGAGTAGAGAGAAAACAGGCGAGAACAAGCACTCTAATTCCAGTGGGCTTTAAAATAAGACAAAATCAGCTTTACAACAATCCCTAGAGGCTCGACCACAGAATAATGCCAGTCACCACCCTGAACGCACAATCTCCAGTGCAGGATCTAATGACTGTACATATTATTGTTATTATTATTATTGTTATTATTGTTGTTCTGTAAACATGTTGCACAAGCTTAGCCTTTTTGCGTTCTGTTGTGTGTGGCTGTAAAACCCCATGCTTTGTGAAATGAGAATCTTGACATTTTTCTTGTGAAATTTGGAAAATGTGATCAATTGAAATCAACTGTGTTTTGTGTTCTCTATGTCAAAGTTTAGTTTTATATTGAGAATGTTAACTTATTGCTTTGTATCTTGGGAAAAAAACTTTGTAAATAAGTTATAAAGTTTCTTTGAGACAGTAAAATTATGATTTCTTGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000144355-DLX1:NM_178120:2
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.315 A=NA C2=0.556
Domain overlap (PFAM):
C1:
PF0004624=Homeobox=PU(73.7=62.7)
A:
PF0004624=Homeobox=WD(100=63.2)
C2:
PF0004624=Homeobox=PD(22.8=15.3)
Other Inclusion Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCAGTACCTAGCTCTGCCG
R:
GGGAGACAAGAAGGAGACGGG
Band lengths:
351-1500
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)