HsaINT0048740 @ hg19
Intron Retention
Gene
ENSG00000064195 | DLX3
Description
distal-less homeobox 3 [Source:HGNC Symbol;Acc:2916]
Coordinates
chr17:48067369-48070954:-
Coord C1 exon
chr17:48070764-48070954
Coord A exon
chr17:48069229-48070763
Coord C2 exon
chr17:48067369-48069228
Length
1535 bp
Sequences
Splice sites
5' ss Seq
CAGGTTGGT
5' ss Score
8.08
3' ss Seq
CCCTTTCTTCTCTGGCCCAGGTG
3' ss Score
9.86
Exon sequences
Seq C1 exon
TGTCGGTGAAGGAGGAGCCGGAAGCAGAGGTGCGCATGGTGAATGGGAAGCCCAAGAAGGTCCGAAAGCCGCGTACGATCTACTCCAGCTACCAGCTGGCCGCCCTGCAGCGCCGCTTCCAGAAGGCCCAGTACCTGGCGCTGCCCGAGCGCGCCGAGCTGGCCGCGCAGCTGGGCCTCACGCAGACACAG
Seq A exon
GTTGGTGTTTGGCTGTCCAGGGCCGCGGGGGCGCGCGGGACCCCGTAGTTCCCCGCGCGCTGCCGAGCCTGGCTGGCCACTGAAGGGCCCTGCGGGCTCCTGGAACTCTTGCCTTTGGGATGGGGGCCTGCGAGGTTCAACTTCGGTGGGAAGGTTCTGCGTTAGCACGTGTACAAGTGAGCATAGTTGTGAACCCGTGCAACTGTGTATGTTCCCCTACTCCAGAATTCCCAGCTCCCAAGTCCCCCAGCAGTGCTAGTCACTTAGTAGGAGTCCACATCGTGTTTTCCCTCCAGGCTAGGCATGTGTGCAGACTGTCTGTGTGCATGTATAGGCGAGTGTGTTTGCACACATGCTGTGTGGGTCTGCATGCACCGGAGGATGCTCATGTAAGGAGTGTGATCCTGCCGGGGTCATTGTGCATAACGATGGGGGCATGTGTGTGTGACTGTGCGCCCTGAATGTATATGCGTTCTGAATGCATGTTCAGAAATGTGTGCTTGCATCAAAATACCACATTCCTGCTCAGCACTTGAACGCTCAAGAGAGGCCAAATTCCCTACCTGAAGGAGATGGGGACTCAAAAGTGAGTGCCGCACCCCCACCCTCATCCAGTCCCTAAAGCCCCCAGCAGCCTGTCACTGCTCAGGGGAGGAGCAGTGGATGCCTGGCTCCCTCCAGGTGTTGACAGGCGGGCCTAGGTTGTGGCTGTGGCTGCGTGGGGCCCCATCCGCCGGGAATCTGGGTCACCTGGTGAGGAGCTGATTCATTGTTTGTACCAGTCATGGGGTGGGGAGTGGCAGGGGGAGGGGGAGATACCCCAGGGGAAATTTGGGGAATCATGGCTCACCTGCTCCTGAGTCCCCAGGTCACCCCCATTATCCAGCCCGAGCCCAGGAGAACTTCTCCACACCTGAGTGTGTGAATGTGGGTGCTCATGTTGTGGGGTGCTTATCTGGGTGTATCTGTGTCTGCGTGTATTTTTATTGTCTGGTGTCTGTGTGTGAGGCTGTGAGTGGGAACGTGGCTGGGTATGGAGATGTGTATGTGGGTGTGTTTGTCTCTGTGTATCTGTGCACCTCTGCTTATGGGTGTCTAATGTGAATGAAATGCTACAAACCGTCCATCTCCCACCTCAACGGCCTTTTATTGAGTGCTTACTACATACCAGGCTGCTTTAAGTTTTTTATATGTCGTACCTTATTTGAGCCTCAGAATGACCCTATGAGGCAGGTAATAGTGCTGTTCTCATCCCCATTTTGCAGACAAGAGGAAGTCAAGAACAAGAGAGGTTAAACAACTTGCCCAAGGTCACGCTTAGTAAGTGACAGAGCAGAATTTGGACCCAGGCAGCTGAACGTTCCTAGCCACAATTCTATCCCAGATCCAAGAAACTGGGAGTCAGGAGGCCTGTTTTTTGCCTGATTCTTATGTGAAATTGGGTTCTGGCCTTTCTTTTTCTTGGCTAGGTTCTTCCCAGGGTTGTTTTAGCATTCTGAGAGGCTAACTAGCTACCCCTTTCTTCTCTGGCCCAG
Seq C2 exon
GTGAAAATCTGGTTCCAGAACCGCCGTTCCAAGTTCAAGAAACTCTACAAGAACGGGGAGGTGCCGCTGGAGCACAGTCCCAATAACAGTGATTCCATGGCCTGCAACTCACCACCATCACCCGCCCTCTGGGACACCTCTTCCCACTCCACTCCGGCCCCTGCCCGCAGTCAGCTGCCCCCGCCGCTCCCATACAGTGCCTCCCCCAGCTACCTGGACGACCCCACCAACTCCTGGTATCACGCACAGAACCTGAGTGGACCCCACTTACAGCAGCAGCCGCCTCAGCCAGCCACCCTGCACCATGCCTCTCCCGGGCCCCCGCCCAACCCTGGGGCTGTGTACTGAGCACCCATCTGGCCTGCACCCTTGACAAAGGACCCCAGGACCAGGCAGAAGGCGCCTCCGTCCTAGCCACTCAGGAATCATCGAGGAGCACAGGGAAAAGGAACTCCCTTTCCCCCTCCCTTGCCCCTTCCTCCAGGGACCCAAGCGCTTCCAGATGACAATTGCATGGACCAAGGATGCCCCCTGAACCTCCCTCCCTCTGCCTAGACACTGGGGTACCCCTCCAGATGTGGGGACATTCCACCCCAGTGGGGACAGCCATTCCCCTACCTGCTCCAGGAGCCTGGATTGGCTTTAAATGGCTCATCATCTTCCAGCTTCTTAAACTTAGTGCCTGTTCCCAGACTGGAGACCTTGGGATGGGGGAGAGTGTGGAGGGTTTGCGGGTCCTGCCTGTGCTGGGGCACCTGGCACCGTGGATCTTAAAACTTGCCAGGCCTAGTTCCTCCTGAGCCTCTGGTGGTCTCCCCCTGCTCGAGCGGCCCCTCGGCCAATAAGACAGTGGACATCATGACGAGGACTCCGGGTGGGGACCTGAACTGGTCACCGCCCTGCACTTCTAGCCCTCATTTAAGATTTGAGGGTGAAACCAAAGAAAACCCCCTAAGTGAGGGAATCTTTTAATATTTGTGGCTTTAGAGGAAAGAACTAAAGGAGCCATCTCTCTCCCCTCTCCTCCGTTCCGAGAGGAGGGGTGGGTCTCAGACGTTTTTCCTATGGACTTATTTCTTCCATGTCCAGGACTTTGCACAACTTTGGTTTTAAAAGCTGTTGAAAAATAGGAAAACAAAGGGCATTGTTCACAGATAGGGCCAAGTCTCCCCTTGCAAGGGTGCCTCTGTTCTGTCCCTGCCCCCACCTCACCTTCTCTACTCCTCCAGTAAGTTGGCAGTTTTGGTGCCAAACCCCAAATCTCCAAAGAGACATACCAGGCAAGACAAACCCCCAAACACCTCCTTTCCGGTGGCCTTGGAAACAGATTGCTCCGAGCTGGAGAATGTCGGGTGAGGTGTATGGGAGAGGAGGGGAGAGTTAGAACTTGTGCCTTTGGGAGTAAGGGGTAACTGCCTGGAGGGCTGGTGGCACTGCCCCTCCCTGACCCAGACATCCCACCAAAGCTAACTTTCCCCCACCCCTGATGCAGTAAAACATTGAAAAAAAAAAAAAAGGAGAGGTAGAAGACTGTAGCTATATATATAAATATATAGTAAGTTTTTTTTTTTTAAGAGCAACAGAGAGAAGCAGCCTCCTCCCTGCTGCGGTTTCCTATTTATGTGGCCATGTTCCTCCTGGACGGATCTCCCTGTGTGTTTCAAGCTGAGAGATGTGGGCTCCGGCTGGATTTGGGTTTTGTGGGAGGTGCAGGGGCCAAGAGAGACGTGGTAGGTCTCCAAGAGTCCCACCCGGGGGGGAAGAAGCAAAGCCATCTCCCACCCCCTCCCAGCCTTCTCATTTCTGCTTTCTTACTGGACTCATCTTTATATATAATGTTAATAAAAAAGACGAAAATAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000064195-DLX3:NM_005220:2
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.328 A=NA C2=0.852
Domain overlap (PFAM):
C1:
PF0004624=Homeobox=PU(73.7=65.6)
A:
NA
C2:
PF0004624=Homeobox=PD(22.8=11.2)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCCAGAAGGCCCAGTACCT
R:
TGGGGTCCACTCAGGTTCTG
Band lengths:
342-1877
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)