HsaINT0048777 @ hg38
Intron Retention
Gene
ENSG00000187908 | DMBT1
Description
deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:HGNC:2926]
Coordinates
chr10:122620253-122621380:+
Coord C1 exon
chr10:122620253-122620291
Coord A exon
chr10:122620292-122621056
Coord C2 exon
chr10:122621057-122621380
Length
765 bp
Sequences
Splice sites
5' ss Seq
TAGGTAAAT
5' ss Score
6.62
3' ss Seq
GTTCTTGTGTTCCCCTGTAGGAT
3' ss Score
11.37
Exon sequences
Seq C1 exon
ATACTTGGCTGACCACCAACTTACCGGCATTGACAGTAG
Seq A exon
GTAAATAATCCTCTCGCCCCTCCCTAGGGCTCACTCTCTACCTCTGGACAAACGTTTCTTTTGAAAATGAAAGAATGAGGCTCAAGCTGGCGCCTCTGTTTTTCATGTTTCCGCGAGTTGCCTGGGGAGGTAGACTCCCTGGGAACCTAGTCCTGGGTCAGATGTTGGAGGCTGGAGGGTGCTGGTGACCTGTCTCCCCTGGGATTCTGTTTTATGTAGTCAGGAAAGATCCTCAGCCAGGTGCTCAGGACAAGCCCTGGAGGGCTCCCTAATCCTACTGGGACCTTGTTCCTGGCCCTCAGGCCACAGGCTGCAGACCTGCGAATAGTGGGGAAAGTGCCTGTCCCCATAGCTGTCTGGCCAATGTCCTACCATTCCTGGCACTTTGCTAGAAGCCAGAGAGGATCATGTGGGTGCCACCAAACTCCTGAACGTGAGGCAGGTCTTGGCCTCCTATCTGGAGCTGTGCAGCTTCATCCTGTGTGAGAATGGAGCTCAGAATGAGGAGTGAGGCGTCCATTCCTGTCACCTCCAGTGGGGTCACAGGTGCTTCCCCAATACTTGAGCTTCCATAGACTTGGGTGGAGTAGGACATCACTGCTTCTTCCACTATCATGAAGCTGAACCTCTGTCTGTATTCATATTCAAAGGTGATTACCTGCACACGTGACTTTGGCCATTAGGAAGTGCCCTGAGTGTGGAACATTCCTTAAATCCTTGACCTCATAATCAGTATGGATGAAGGGTTCTTGTGTTCCCCTGTAG
Seq C2 exon
GATCTGAATCCAGTTTGGCTCTGAGGCTGGTGAATGGAGGTGACAGGTGTCGAGGCCGAGTGGAGGTCCTGTATCGAGGCTCCTGGGGAACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAATGTGGTCTGCAGGCAGCTGGGCTGTGGCTGGGCCATGTCGGCCCCAGGAAATGCCCGGTTTGGCCAGGGCTCAGGACCCATTGTCCTGGATGATGTGCGCTGCTCAGGGAATGAGTCCTACCTGTGGAGCTGCCCCCACAAAGGCTGGCTCACCCACAACTGTGGCCATCACGAAGACGCTGGTGTCATCTGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187908:ENST00000338354:40
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.071 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0053013=SRCR=WD(100=89.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACCACCAACTTACCGGCATT
R:
CAGATGACACCAGCGTCTTCG
Band lengths:
348-1113
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development