HsaINT0048781 @ hg19
Intron Retention
Gene
ENSG00000187908 | DMBT1
Description
deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:2926]
Coordinates
chr10:124385449-124389509:+
Coord C1 exon
chr10:124385449-124385481
Coord A exon
chr10:124385482-124389355
Coord C2 exon
chr10:124389356-124389509
Length
3874 bp
Sequences
Splice sites
5' ss Seq
CAAGTAGGT
5' ss Score
7.33
3' ss Seq
GTCCCCTCTCTCCTCTCTAGGAC
3' ss Score
12.83
Exon sequences
Seq C1 exon
ATTGGTGGCATCCAACAACTACAACCACTGCAA
Seq A exon
GTAGGTATCACATTTTCTACCTGAACCATAGGTCATACATTTCTTATCCCCAAGCTTGGCTATCCATGAGCGAATGCTCTGCCCCACCCCAGCCTTCCTCAATCTGCACATAGCCCTGGCCTGTCCCACTATACCCTTCACCTCTTCATTTGAATCAATGAGATAAGTATTCTTAAAATAATAGACTTAAAGGCTTTTATTTTGGGGGGTATCTCCAAAGCTTTAGGAGGAAGAAGGGAGACAAATAGTAAATGGATAATTTTACTACAAATTATGCTTTTCCATGTCATTTTTATTTCACCATATGGCTATGTTTCAATAGATTTTCATTGCTTTTAAAAAATAATAGGGATACTTTTCTGTGTTATTAAATCTTTTCTCACAATCATTTTAAGTCCCTGTATTGTATTCTATTATACAGATATGCCATGAATTATTTGACAAATCATCAGATGCTAGATATTTGTTTGTATTTCTTCATTACTGTAAATGATTTTGTGATGAAGAATATTTTTATAGATAATTTTTTTGCATACCTCACTAATTTTTCCTTTAGGATATAAATGGGTTTACTGGACCAAAGTCAATGTCATTGTAGTGCCTGGTACATAGAATGTACTTCATGCATATTAACTTTTACTGTGTTAGGTATTTTAAGATCTTGCTGTGTGTATGGTCAAACTACCATCAAGAATGGTTGTAAAATTATGGAATGATGTAAGAGACAAACTGATCTTCTTCCTCAGAGCTCACAATATTATTTTGTACACAACAAACTAGAAAATTACAGTTGTGACAACTGTTTCCAAGGAAAAGTTCAGTGTGCAAAGAGGAAGTATTAGTAGAGATCTTCCTTGATTGGGGAGTTAGGGGAAGTTCCTTATGGAAGTGACATTTAAGCTGGGAGTTAATAGAGGAGCAGGTTCATTTGCTGAAGTGTCTTCTAACCAGAAGGGATGCTTTGAAGGCCCTAGGGTGGGAAGGAGCTTGGCTCTTTGAAGGAGGGTGGGGTGCGGGCAAGGAGGGACTGCAGGAAATCTGTCGGGTGAGGCCAGATCATTCAGGGCCTTGTGGGTGGGTTAAGACTCCCATCTTTATCCTAAAGGTAGGGAGGCTGCAGAAAGATTTTAATCTTGAGAATTAGCTAATTGGAAATATATTTGCAAAAGATCATGTTTATCTTTTCTGCCAAACTGCATTTCCTGAAGGCAGGGGCCATGTCTGCCTTTTTCATAATGTATCCTTATTATCTAGCATTGTGTCTGCCTTTCAAGAACTGTTTATTGAAGGAATAAATGAGTGAATGAATGAATGGATAAATTAATGAATAAATACATAATTACTGTTGGCATTTTGGCATACATTCCATACACTGTATACACACACACAAACACACACACACACACAGTATGGCATGCTTTATATCCCATTGTATAACCCATCATTTTCATTTAAGTGTATATAATACTTTTTTCATGACCTTAAAATTAGCATTTTTATAACATTGAAATTATTTGTATAGAAGAAGGTTTAATGACTATATGATTTTCCACTGTATAGATATATCATCATTTAGTTAAACGGTTACTAATTGTGGGGCAAAAACATTGTTTCCAATTATATTTTATAATGTTAAGTGACTATATACAATAGCATATTTTATAACCATTTATATTTAATGATTAGAAATATGTAACTCGTATCCTTGTCTCTGAAAGTTTGACTTTATCCTTAATTATTTCCCAGTGTAGAAATAGAAAGGGAGGGCAGGCCACATGATCTTCAAGAAACACTGTCTTCCCATCAAATGGGAGAACGTATTTCTATCTCATAAGGGACTTGTATCTAGGATATATAAGTGACTCTTGTAGTCAATGATAAAAAGTCAAATAACCCAACTGAACAATGAGCAAAAGACCTGAAAGATATTTCTCTACAGAAGATTCACAGATAGCAGAGAAGGCATTGGAAAGATGCTCAATGTCATTAGCCGTCAGGGTCATGCAAATGAAACACCCAGTAGGTGGGCTGTAGTCAAAAAGCCAGATAATAGCAAGTGTTGATGAGGATGTGGAGAAATTGGAAACCTTATGCACGGCTGCAGGGAATGTAAAATGGTACAGCCACTTTGAGAAGCAGTTTGGTGGCTCCTCGAAAGGTTAGACCTGGAGTCACCATATGACCCAGCAGTTGTATTCCTAGGTATATACCCAGGAGAAATGAAAACATATGTCCATACAGAAACTTGTATGTGAATGTTCAGGACAGCTTTATTCATAGTAGCCAAATGTGAATGCAATGCAAATGTCCATCATGGTGAATCGAGAAACAAATATGATATGTCCATGCAGTGGAGTATTATTTGGCAATAAAAATGAATTTAATAGTGGCCGGGCGCGGTGGCTCATACCTGTAATCCCAGCATTTTGGGAGGCCAAGATGGGCGGATTGGCTGAGGTCAGGACTTCGAGACCAGCCTGGACAACGTGGTGAAACCCTGTCTCTACTAAAAATACAAAAATTAGCTGGGCATAGTGGTGGGCGGCTGTAATCCCAGCTACTTGGGAAGCTGGGGCAGGAGAATCGCTTGAACCCGGGAAGCGGAGGTTGCAGTAAGCTGAGATCGTGCCACTGCACTCCAGCCTGGGTGACAAGAGCGAAACTCCATCTCAAAACAAAACAAAAGAAAAAAAAGAATTTAATATTGATTTATGCTACAACATGATGAACTTTGAAAACACATTGAGAAGTCAGTCAAAAAAACTACCATATTGTACAATTTGTTTTATATGAAATGTCCACAATAGGCAAATCTATAGAGACAGAAAAGTAGATCAGTGGGTGCCAGGAATGGAGGGTGTTGAGAAGAAATGGGGAGTGATTGCTAATGAGTACAGGGTTTCTTTTTGGGGTGATGAAAATAATCTAAAATTGACTGTGGTGATTTCAGAGCTCTCAGTATGCTAAAAACCATGGACTTATCCCCTTAGAAAAAGTAAACAAAGAGTTATGAAAAAGAAAAAAAAAGACGTTTTAATTTCTATCACTGAGTGTGCACATGTTTTTAAAAAGTTTTTATTACTATAAACCAACCAACAAAATGTTTGACCACTTAATATTTATCCTTTTCTGATAAATAACAATAGCTAATATTGCTGGGTGCTTATGTGCCTGGCACTCTCTAAGAGTTTATATAGACATAGAAACCTATCTTATGTTTATGTATAAATGTTCATATATACATATCTTATTTAATACCCTCATCAGACAGATGAGGCAGATGCCATTACCACTCTCATTTTTCTGATGAGGAAACTGAGGCAGAGAGGTTAAGTAACTGGCTCCAGATCATGGAGCTGATAGAGGCAGAGCCAAGATGCAAACCCAGGCTTCTTGTTGCAGAAACCCTGCTCCTAACCCAACGTTGTGCTACTTGTGAATTGGCAGAGTCCTGTGCTCATGGAAGACGCTAGGGAACACACTGTGTTATGGAGTGCTCTCCACGGGTCAGCACTGTGTTCAGCCAGGACTATCCCACGTCCCTGTCTGTAGCTGATTGAACAATGATAGCTGTCACTTTGTTGCTTTCTTGGCATTTTTGCTAGAGGTGACACATGCTCCCTCTGAAGCTTGGGTCACCTCCTCGCAGAGGGTTGCTGTCCAGGCCTAACAGGGAAAGCAGGGACTTGAATCAAAGCTTCTAATGTTGGGCCACCTAGAACCAGGCCCAAGAGAGGGGACTTGTTTACAGGGAAAGTTAAGTCTTGTTATAAAGTGCAGAAGATGAAACTGGATGATACTTACACAGATGATTCCTTGTCACAAAATACCTGAAGACCTGGTACAATGGAGATGTCCCCTCTCTCCTCTCTAG
Seq C2 exon
GACCCTCTTCAAATTGTGGTGGCTTCTTATTCTATGCCAGTGGGACATTCTCCAGCCCATCCTACCCTGCATACTACCCCAACAATGCTAAGTGTGTTTGGGAAATAGAAGTGAATTCTGGTTATCGCATAAACCTGGGCTTCAGTAATCTGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187908-DMBT1:NM_004406:30
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.250 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0043115=CUB=PU(42.2=88.5)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)