HsaINT0048789 @ hg38
Intron Retention
Gene
ENSG00000187908 | DMBT1
Description
deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:HGNC:2926]
Coordinates
chr10:122637128-122640449:+
Coord C1 exon
chr10:122637128-122637312
Coord A exon
chr10:122637313-122640039
Coord C2 exon
chr10:122640040-122640449
Length
2727 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAGC
5' ss Score
9.88
3' ss Seq
CTCTTGCCTGCCTCTCCTAGGCA
3' ss Score
8.74
Exon sequences
Seq C1 exon
ACCTGCTCTGTCTGCCAAATCACATGCAAGCCAGTGTGAGCAGGAGCTATCTCCAATCCTTGGGCTTTTCTGCCAGTGACCTTGTCATTTCCACCTGGAATGGATACTACGAGTGTCGGCCCCAGATAACGCCGAACCTGGTGATATTCACAATTCCCTACTCAGGCTGCGGCACCTTCAAGCAG
Seq A exon
GTAAGCCTGGGGCTTCCCATTCCATTTCCCAGTGCACAAGCTTTCTTAGAGCGGTATGTCCTGTGCTTCTTGAATTCTGGGGATGAAGAAATTATGATTTTGGGATAATCAGGACATAATTGGAATAAAGGAAGATAAAAAACCTTTGGTGCTATGATATGGCTGCAGCTACTTCCAAATAGGAAGAAGGAAGCTGAGCAGAAAGAGTATCTCCAGCTGTGTCCAGCAGAGAGGGCTTCTGGCAGACCGCCACTCCCATCAGCAATAACAACAGCAGCTCCTGGAGCAGCTCCAGATTTTGCAGGGCCTGAAGCTTATACAGTTAGGGTTGGGGGTGAGAGGCAGGTGTTGAGATGGGCAGGGGCCTCATTAAGTCAAAGAATGCAATATCTATGAACTTTTATAAACTTTGCAAAAACGTATGGCTGTGCAAACACATTGCTAGGCCTTGGAGGAGGCCTGCACATTGCAGTAGGCAGGGAAGAGGGGGCCCAAAAGCTTCAGCTTCATTAGCTCCATAGTCAGCTGGCCTCTGCAGCTACCATTTGTTGAGCTATCACCATCTAAGATGGCCCCCTGCATCCAATTTTGGGTGAAAGTGAAGCCAATATGGTGTGTCCCTTCTCTACAGGCTTGAAGGTGGCTGCAACTATGATTATACTGAAGTTTTCAACAGCCCCTACCACCGATTTCTGTGGTTTGCCTGGGACTTTGCAGATTTTAGCATAGAAAGTCCCACGTTCCAGGAAACCCCTCACTCCCAGGCAAATGAGGACGGTTAGTCACCCTACAAGTGGCAGATGCTGTGATTGGTCCTTGTCATACTCCCCCAGTGAAGGCCTGGCCTTAATTGTGTTGGGTTCTGGCTTGCTGTGAGTTTGGTCAGTGGAAGTCAGTCCACTGAAGGTGACCATTGTTCCTATGCCAAGTGAGCAGCCTGGAGACTCCCTGAGCGGCCCCGCTGAGGGCCCTTCACACCCATTCACACCCATTCACACTCGTTCACACCCATTCACACCCGTTTGGAGCGGCCAGACAACTCTGTCAGCCCTGTTTCTTCTAACTTGGCTGATCATGAATAGCACACGCCACATTCTTATTCCTCCACTCATTTATTTATTTTTATTTTATTTTAATTTTTTAATGACAGGTTCTCATTCTGTTGCCCAGGCTGGATGCCCAGGCAGGGGTGCATCATAGCTCACAGCAGACTTGAACTCCTGGGCTTAAGCAATCTTCCAGCCTCAGCCTCCAGAGTAGCTGGGACTATAGGCATGCACCACCACACCCAGCTAATTAACAAATTTTTTTTTGTAGAGGTGGGATCTTGCTATGTGTCCCAGGCTGATCTCGAACTCCTGAGCTCAAGTGATCCTCCTGCCTTGGCCTCCCAAATGCTGGGATTACGGGCATGAACCACTGCTCCTGGCCTCCTCTATTTCTTTAAATAACCATATTGCCTATCACACTGAGTGCCTCAGGGGCAGGGCCAATGTTTTGTTCATCTTTGCAACCCCCAGTGCCCCTGGTCCTGAGCCTAAGAGTTGATATAGTATTATTAACAGCTCATACAGATATCAGACACTGAACTAAGTGTGCTATATAACTTTTAAAATTCTCAGGACAACTTTATTCCCACTTAATTATGAGGCAACGGAGGCTTGCAGAAGGTAAGCCACTTGCCCAGAACCATATGGCCATGAGCTGCGGGTCTAAGACATAGAAGTAGGGCTGTGCCATCCATGGCTGGAGCTTCCCACAGCTCCACCAGGCTGGCCTGTGATAGTGAATTTTTATCTAAAATTAGAACTGCTTCTTCTGACCAAGAAATAAATCTGCACTCCATGTTCATTATTTGGAGTGGATTCAGAATTTACCTCCATCGTAGGCACCACAGGCAAATGTGACATCCATGCAAATGATCATGTTAATGTACAGGGTTCAATGGAAAGCACTTGAGAGCATCTTTGAAAGAGTAAGAAGGGTCATACTGTCATGTGCGTCCATGTGAAAAGACCACCAAACAAGCTTTGTGTGAGCAATAAAGCTTTTTAATTACCTGGGTGCAGGTGGGCTGAGTCCAAAAAGAGAGTCAGCGAAGAGAGATAGGGGTGGGGCCGTTTTATAGGATTTGGGTAGGTAGTGGAAAATTACAGTCAAAGGGGGTTGTTCTCTGGCGGGCAGGGGCGGGGGTCACAAGGTGCTCAGTGGGGGAGCTTCTGAGCCAGGAGAAGGAATTTCACAAGGTAACGTCATCAGTTAAGGCAGGAACCAGCCATTTTTACTTGTTTTGTGATTCTTCAGTTACTTCAGGCCATCTGGATGTATATGTGCAGGCTTGGGCTCAGAGGCCTGACAAAAGGGTTTATTGCGGTCGTATGGTTTAAGTCATACGGTTTATTGTGACAACTGTTGGCACTGAAATATAAAGCAAAAACAAATTTTTAAGACAGTTTAAAGTCAGAAAATGTACGCTAAGAGCAGGTGGACAAGGTAGAACCCCTTCCTGTGGGTCTTCCCCAGACCTGGACCCAGAGTGTAAGCTCTGGCACCCTGTGCTGGCTCATAGCCAAAGGATAGGCACGTGCCATGGCCATCTCTGAGTGGTTCTGGGAGGGGTGGAAGTCTTGTTGAGTCACGTCCCTCTCATTCACACCCAAATCAGCTATGGGATTCCCTTAGCAGGTGACATGTGCCTGACTCTGCTCTCTTGCCTGCCTCTCCTAG
Seq C2 exon
GCAGACAATGACACCATCGACTATTCCAACTTCCTCACAGCAGCTGTCTCAGGTGGCATCATCAAGAGGAGGACAGACCTCCGTATTCACGTCAGCTGCAGAATGCTTCAGAACACCTGGGTCGACACCATGTACATTGCTAATGACACCATCCACGTTGCTAATAACACCATCCAGGTCGAGGAAGTCCAGTATGGCAATTTTGACGTGAACATTTCCTTTTATACTTCCTCATCTTTCTTGTATCCTGTGACCAGCCGCCCTTACTACGTGGACCTGAACCAGGACTTGTACGTTCAGGCTGAAATCCTCCATTCTGATGCTGTACTGACCTTGTTTGTGGACACCTGCGTGGCATCACCATACTCCAATGACTTCACGTCTTTGACTTATGATCTAATCCGGAGTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187908:ENST00000338354:51
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0010018=Zona_pellucida=PU(23.0=95.2)
A:
NA
C2:
PF0010018=Zona_pellucida=FE(53.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development