HsaINT0048793 @ hg19
Intron Retention
Gene
ENSG00000187908 | DMBT1
Description
deleted in malignant brain tumors 1 [Source:HGNC Symbol;Acc:2926]
Coordinates
chr10:124333231-124336238:+
Coord C1 exon
chr10:124333231-124333278
Coord A exon
chr10:124333279-124335914
Coord C2 exon
chr10:124335915-124336238
Length
2636 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACG
5' ss Score
10.19
3' ss Seq
AATTCTGTGCCTTCCTCTAGGAT
3' ss Score
11.44
Exon sequences
Seq C1 exon
GTTCTCTGATTCCCTCAGAGTCAACCCTGGAGTCAACTGTAGCAGAAG
Seq A exon
GTAACGTCTACTATGGGGGATCCCTGTAGGCTCATTACCCCCCTGCACCCCTAGGTTAATCTCTGATTCAGATGAGGTGCAGAGGGCATAGAAAGTAGGGTGCTTAGCTCCCACGAGGGGCCCTTCCACAAAAGGCCTCAGGTCTGAACAGGTATATCTTGCATCGATCATGTCTGAGACTGAGGAGGAATCAACTTGAAGACGCGTCTCCAAGGAGTTCTCAGTGGAGCCTTTTATTCTGTCTCTAGAGATTCTGTTATCTTTGCTTGTTGCTCACTCCTGTGTTCCTCACCCAGCTGTGCTCATCCGTGGCCAGCCTAGGGTTCTGGATCTCTGGCTACAGGGCCTTGAGGGTCAGGTGCCTACCTGCTAACGTAGCCAAATTGCTAGGACAGCATCCTTGCCCTTGCCCTTTCTTTAAGCCTATATTATGCCACCCTTGTTTCTTCTTAACAGAGAGAAATCACAATCCTTCAGCTCATGGGCATCAGAGCTCATGTACTTCCCCCTTGGGTATCTCCAGTGAGAAATCTGGGAGACATAGTCAATACATCCTGGGATTCTGGCAGCCTGGGCTTTGGGAAGGGAAGTCACTTCCCATTTCCCATGGGAAATCTTGGCCCTAGGAGAAGCTCAAGGACAACATTCTCACCAAGGCCTCTGCGCTGCCCAGGGTTGGCATGCAGTTGGGAATGCTGATGGTACATGCATCGGGCCCTCCTGTTCCTCAGGTCGTCTTCTTTCTTCTCCCTTCTCCCTCTGGCCCATGGGGTGAGGTCTGACTTAACCTCTTCCTCTTTCCTATGATGAAGGACACAGAAGACACTTGAAGTGAGGGTGAGACTGGCTTTATTCTGACTTAGCCATGTCCCTTCGCAAGATTCCCACATTTTCTTATTTGCAGCAGCTATAAGAGGAGAATCTGTTCCTTCCTCTTGAGTGGTTTCCCCTGAGGTCCCTGTTACATGTTAAGGACCACACCTTGGTGGGACAAGCCCTTTGGTATAACTGGTCCAGCCAGGGATGGGAGTGAGGGGGCAGAGGTATTTGGCTGATCTGCCTGTCACACAGGACTGCAGATAGGACTTACCTGGAGTTGCTCTTATCAGGAACTCTAGTGTCAGCTGGGAGTCACATTTCTTCTAGATCTGGAGACCTCACGTAGCAGCCCAGTGGAGAGCTCAGACAGAAGCTGAGTGCTGTGGCTGCAGTGGGTTAAGGGTAACTCTCAGATCACTTCCTCTCCAAGCCCCAGCACTCAGTCAGCTCCTGTAGGTGCCCTGGACAAATTCCAGGGCTCTGGAGCAATTCAAAAACGGAGATTCCAAGCCAGTACCTTACTTAAAGGGGAATATTAGAAGCATTTCTGCTAATGTGAAAAACAAGGCAAGTATGCCCTCCATCTCCACTGCTGTTCAATGTTGTACTGGAGGTAGTAGCCAATGCAATGAGAGAAGAGAAATCAATTAGAGGCCTAAGCATGGGAAAAGTTATTTTTGCATCCCTCTTCTGGAGTTCTGTATAGGTTACATGTAGGCACATCGGAATCAGAGTGAGTATGTTGGTACAGAAATATTTCCTCCCCAAGCAGCCCTTTAGAATCAAAGAACTCAATGCTAGACAGGTTTCTTGACTTTCCCAAATTTACACAGCAAGACAATATCCAGATCAGGAGTGATGGCTCCTCAGCAGATCCTAGTTTACTTTCAGCCCATGAGTGTCTTCAGAGGAGACCTAACTTTATATTTTCTGGTTTTTTTTGGGGGGGTGTGGTGGGGTTTGTTTTTCATCTTCTACAATTGGCAAAAGCAGAGACTACCACTACAAATACTGAGTCTACTGTTGTGACAGGTAATGAGTAACTTTGAATCCCTTTCTGTAGGTCATGTTGCCAACTATATCCATGGGCTTTACTGTTACTCAGGAAAAATTTTAGGGAATGGGATGGGAGGGAATGTTGTGAGTACACAGTGACCTTCTGGATCCCAGAGGTCAGCTAGAGTGAAGCTTCCTTCATTGCCCATGTTCCTGGAGGTAGGGAGAAATCAGTCAGAATATGGTGTCTCCAAGAGCCTGTGTGCTTTGGAAGCAGAGACCAGTGGGATCAGTCTCCAGTCCAGAGTGACAGCCCAGCTCCCCCATCTCCACAGCTCTGTGCTGACCCTAACAATCCTGGCCCTGAGGAAGGCTATAAGGCCAGGAATATCACGTGACAAATGTGCTCCAAACCAACCTTAGAGCTGCAGATACACATCAGAGCTCCTCCCGGGACATCTTGATGTTATCGTGCTGCTCTTCAGTGTGGGGTGTTGTGTGTCCCCTGTCTGAGGGAATCAGGCAGAGCCCATGGTCTGCTTAGAGAAGGGTCATGTGTATCTCTAGGTCCCCTCCAGGATGCAGATCAGGAGGAGCCTTTTATTCTGCTCCAGCTGAAGCTCTAAGGCTTGGGTTTGGGCCAAGCAGTCACTGTCCTCTTCCCCATGAAGAACTCTAACCTTAAGGCCTGTTAAAGCCCAGCCCAATTAGAGATTCTCTCAAAGATATCTGCCTATGGGGAAGACCCTGAATGCCCTGCAGGCCCTGAGACCTTGTGCCTCAGTAGGAATGTGCAAGAGAAATTCTGTGCCTTCCTCTAG
Seq C2 exon
GATCTGATTCTGGTTTGGCCCTGAGGCTGGTGAATGGAGATGGCAGGTGTCAGGGCCGAGTGGAGATCCTATACCGAGGCTCCTGGGGCACCGTGTGTGATGACAGCTGGGACACCAATGATGCCAACGTGGTCTGTAGGCAGCTGGGTTGTGGCTGGGCCATGTCAGCTCCAGGAAATGCCTGGTTTGGCCAGGGCTCAGGACCCATTGCCCTGGATGATGTGCGCTGCTCAGGACACGAATCCTACCTGTGGAGCTGCCCCCACAATGGCTGGCTCTCCCATAACTGTGGCCATGGTGAAGATGCTGGTGTTATCTGCTCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187908-DMBT1:NM_004406:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.310 A=NA C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0053013=SRCR=WD(100=89.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)