HsaINT0049281 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123929275-123929759:+
Coord C1 exon
chr12:123929275-123929484
Coord A exon
chr12:123929485-123929663
Coord C2 exon
chr12:123929664-123929759
Length
179 bp
Sequences
Splice sites
5' ss Seq
CAGGTGACA
5' ss Score
5.49
3' ss Seq
GCGTGTTCTCTTCTTTCAAGGTC
3' ss Score
9.74
Exon sequences
Seq C1 exon
GTTGTCACCGAGCCACCCAATGGGCTGAAACTCAACATGAGGGCAACTTACTTCAAGATCTCTCACGAAATGCTGGACCAGTGCCCGCACCCTGCCTTCAAGCCGCTGGTCTACGTGCTGGCGTTCTTTCATGCTGTGGTGCAGGAGAGAAGGAAGTTTGGGAAGATTGGCTGGAACGTGTACTATGACTTCAATGAGTCTGACTTCCAG
Seq A exon
GTGACAGTGGCTGCTTCTCCTTGGAAATGGCTTCCTTAGGCGGCCCACTTCCTCCCGACTTTCCTCCGGGTTCAACCACAGCAGGGTTGCACCGTTCCCAGCAGCCTTTTCAGAAAAGTATCAGAATGTGAACAGCTTGGTGGGTTTCAGTATAACTGAGCGTGTTCTCTTCTTTCAAG
Seq C2 exon
GTCTGCATGGAAATTCTGAACACGTACTTAACGAAAGCCTTCCAGCAACGGGACCCAAGGATCCCGTGGGGCAGCCTCAAGTACCTAATTGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:70
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(9.7=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(4.3=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCAATGGGCTGAAACTCAAC
R:
CGTTGCTGGAAGGCTTTCGTT
Band lengths:
245-424
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development