HsaINT0049284 @ hg38
Intron Retention
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123931341-123931847:+
Coord C1 exon
chr12:123931341-123931472
Coord A exon
chr12:123931473-123931635
Coord C2 exon
chr12:123931636-123931847
Length
163 bp
Sequences
Splice sites
5' ss Seq
CAGGTAAAC
5' ss Score
7.82
3' ss Seq
GAAAAGTGTCCTGGTTTTAGGGG
3' ss Score
4.92
Exon sequences
Seq C1 exon
AAGCCATCGAGGCCCTCCCGCTTGCCAACACGCCAGAAGTGTTTGGTCTCCACCCCAACGCTGAGATTGGCTATTACACGCAGGCGGCTCGAGACATGTGGGCTCACCTGCTGGAGCTGCAGCCTCAGACAG
Seq A exon
GTAAACTCTACTCAGGAGGACTTCATTAGTTTGATTGGGGTTTTACGATTGCTTCTTGTAGCCCTCCCACGTTGCTGATGCCTTTCCCAGAACTGGAAGGCTCAGGAGGCTCCGGTTCTGCACGTGGATGCCTTGCTTTCTCTGAAAAGTGTCCTGGTTTTAG
Seq C2 exon
GGGAATCCAGCAGTGGTATCAGCCGCGATGATTATATTGGCCAAGTGGCCAAAGAAATAGAAAACAAGATGCCCAAAGTCTTTGACTTGGACCAGGTGAGGAAGCGCCTCGGAACAGGACTCTCCCCCACTTCGGTGGTGCTCCTGCAGGAACTGGAACGCTTCAACAAGCTTGTGGTCCGGATGACGAAGTCTCTGGCTGAACTTCAAAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653:ENST00000409039:73
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.014
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(6.2=100)
A:
NA
C2:
PF0302810=Dynein_heavy=FE(9.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATTGGCTATTACACGCAGGCG
R:
CTTCGTCATCCGGACCACAAG
Band lengths:
258-421
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development