HsaINT0049887 @ hg19
Intron Retention
Gene
ENSG00000115423 | DNAH6
Description
dynein, axonemal, heavy chain 6 [Source:HGNC Symbol;Acc:2951]
Coordinates
chr2:84775412-84777181:+
Coord C1 exon
chr2:84775412-84775541
Coord A exon
chr2:84775542-84777012
Coord C2 exon
chr2:84777013-84777181
Length
1471 bp
Sequences
Splice sites
5' ss Seq
GTGGTAAGA
5' ss Score
8.24
3' ss Seq
TAGTTTTTTTTCTTTTCAAGCTT
3' ss Score
6.95
Exon sequences
Seq C1 exon
ATTATCATAAAGTGCAGAGCAGTGGAAGTTTCATTAATACACCACATGAGTTGCCCACTTATGGAGACTCTGAGAAAATGACATATACAGAACAGGCCAGCAAAAGGCATTATTGCATGAGGCTGACGTG
Seq A exon
GTAAGATTATTCTCATTTTCAAGAAAAATTGTAGTACCCATCTTAAGCTGCATTAAAAATTAAACCCCAGAAAGTGATGACTATGTTAATTTGCATAACTGAAGTAATCATATCACTATGTATATCAAAGCATCATGTTGTATACCTTAAGTACACACAATAAAAAATTAAAATGAAAAGTAGAATCTTTTCTAGGACCTAAGTGATGTCTCACTTGAAAAAAAAAATGGAACCCTTCACCACATTGTTCATGAATGGTGATGAGAAATTTGTGGGACATGGTAACCTGAATGCATGGCCCAGAAGACCCCCTTTTCAAACTGCCACCAACCAAAGCAGCTCTGGGACTGTGAGCTGGTAGAGACAGAGCATGAGGCCAAGGCCAAGAGCTCCTCTTTGATCTCTCTGGCTTTGTTTCCTTCTGGCCCAGCCTGGGCATGGAGACTCGCAGTACAGCAGACTGTGGCAGGGAGAAATCAGGCACACAGATTTATGGACCTCCTCAAGTGGGCCTGAAGGACTTGCTCCATCTTTTTGGTCACAGAAGAACTATAGGCAGCTGCATAACATCACAAAGGTGCACCCAATCCCTAAAATGGGATTTGCCACTGGGAGCCAGAGAGAGAAATATCCCTCCTAGGACCTCACCAGGGGACTCTCATTAGCACTAGCTCTGACACCTGCTTACCCAACTGGATCTTGACCTTGACTGTTCCAGAATTTGGATTTCCCATCATTCTAAAACCGCATGTCTTTGGAACTATAAAATACTGATTATTGTTATTCAGTGCTCACTGACTTAATCCAACTTTTGCAATTATGTAATACATCTTAACTATATCTCAGTTTATATATGAAAATGTCTGTGTAGCAACAGAAATCAGTGAAGCGGTCTCTGAGGCTACCATAGTGGACCTAGAAGTATTAGAGGCCTTAGAGCTCCACTTGAGCAGAATAGTACTATTCTAAATGTCTTGCTGACTCAGTCTGCATTCTAAGTAAGCACTCAAGTAAGGAAACGTAAAATTCAAACCTTTGGGTTAGCAATTGCCATCAACATTTATTCAATAGCAAAGATTTTACACTTTTACTATTAGAATGCAAGTTACAGATGTTGTATGCATCGATTTCTCCTTTAAAGCATCTTTTAAAAAATATTATGGCCCTTTTAGCTAGATAAACTAGATGCATTTTCCCTAACAGCTATATCACTCATTAAATATTCTATTGAAAAGTTAGAATATCTAACTGAATTAATGCTACATATTTGAATATATTTGTGTTTTAAAAGGAAGAATATCTAAGGACAACTCTTCTGGACAGTACATTTCTGATATTGTAATATAATTAAATGGAAATTCAAGGAGAAATTATGATATTTTACATTTTAAATATTTGCTTTAGAGACACTGTCAAAAATATGTAGTGAATATAAGAAACCGAAATTGTATTAGTTTTTTTTCTTTTCAAG
Seq C2 exon
CTTTATTCGTCTAAACGACTATCTAATTGAGAACACAATGCACATCTTAACGGTAAATGCTGTTAATTCGCTTTTGAACCATCTCACTGACAAGCTAAAACGAACACCTTCAGCAGATGTCATTCAGAAATGGATTACTGAAGAGAAGCCTGAAGTCCCTGATAAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115423-DNAH6:NM_001370:8
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.068 A=NA C2=0.053
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATAAAGTGCAGAGCAGTGGA
R:
CTTTTTATCAGGGACTTCAGGCT
Band lengths:
295-1766
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)