HsaINT0050025 @ hg19
Intron Retention
Gene
ENSG00000124721 | DNAH8
Description
dynein, axonemal, heavy chain 8 [Source:HGNC Symbol;Acc:2952]
Coordinates
chr6:38903368-38906002:+
Coord C1 exon
chr6:38903368-38903473
Coord A exon
chr6:38903474-38905749
Coord C2 exon
chr6:38905750-38906002
Length
2276 bp
Sequences
Splice sites
5' ss Seq
AAGGTATTG
5' ss Score
7.76
3' ss Seq
TTTCCTGTTTTGAATTTCAGGCT
3' ss Score
9.68
Exon sequences
Seq C1 exon
GAGTTAGAGGCTGAGAGGGTTAAACTTTTGGAGGATGTTACTTTTAATAAGCGGAAGATGAAAGAACTTGAAGATAACCTCCTCTATAAATTAAGTGCTACAAAAG
Seq A exon
GTATTGTGTTATTAAGAAGTAATGAAATAACGGATTCTGAATAAGGATTTCATTTACACTCTTTTCAATGCCCTCATGACTATAGATGTTAGGAAATACTCATGTTATCAATGCAAAAACAAGCAAGGCAATTTCCATCTAGACATTAAAGAGGGACGGCAGAGAATCTGATTTTTGAATTAGCAAATAGAGACTGAGCATCTGAGAATAACACAATTTTCTTGATATAATTGCTTTCTCCTGAGAAAAATTAGGGCTCCTGATAGAGCTAGATAACTCATTATAGGTTAATTTGCTTGCCCCAAAGAAACTAATGTGCTCAATCTATTTTTTTTTTTTTTTTGAGACAGAGTCTTGCTCTGTCTCCCAAGCCAGACGTGGTGGCTCATGCTTCTAATCCCAGCACTTTGGGAGACCAAGGCGGGTGGATCACCTGAGGTCAGGAGTTTGAGAACAGCCTGGCCAACATGGTGAAACTCAATCTATTTTTTTTCAAATTGACTCTTTCATTTGGCATTGAAATGCAGTTATTGCAACGGGTTATGACACATGTAATCCATGTCAGAAGAGCTTGGGTACCAAAGGCCCAGCTTACCCTCTACTTGGCTTGACCTCCCACTTTAGATGGGAAAGACAGGTTCTCCTCTGGGCAGCCAAATCATCATGCCACACCTCAATTTGAGGATGTACTCTCTCTGCAATATATAAAAAGAAAATTTTATCCAAAGAAAATAAAATCAACAAACATATTGTTCTGTAGCAGACAAATCACAGAAACCTGAATTCTACTACCTTATTAGAAGTGAATGAATACTTCACAACTGCACCTTAATCCCGGGATGTTATTTAAACAAGTCTGACCTTCCAGAAGTACTGTACCTTTATGGTGAGCTTAGTGAAAAGTCCTTTTATCTGCCTACTCGCACTGCTCCCGCTAGTGAAGTTGTCTGTTTCTTGGTCCAGTGACTCCTCCCAGCCATTTGGGATACCCCTGGGCATTAAAAATATAGCAAGCAGAGCTGAGGGCTGCTCCCCTAGTCTAGCCAAGAGTGTGCTGGATCAAGACCTCTCTCCTTGAGGTTAATCCCAATTTGGACTTCCACAGTAGACAGCATACCCGTTGGAGTAACACAGCCCTTCCTGCAGCACTTGTCTGCCATCCCGAACTCTAGGGTAGGCCAGAGTGCTGCTGTTCGCAGATATGGGAACTGTTCGCAGATATGGGGACTGTTAGCTCAGTACATCCAAGGTGTCTTTCCTTAGATTTTAATTAAAAACCAAATTCATTGTCATAAACATGCACTATTTCCATTAAAAACAATAATAAAAAAAAAGGATGAGTTCATGTCCTTTGCAGGGACATGGATGAAACTGGAAACCATCATTCTCAGCAAAGTAATATCAGAATAGAAAACCAAACACCGCATGTTCTCACTCATAAGTGGGAGTTGAACAATAAGAACACATGGACACAGGGAGGGGAACATCACACACTGGGGCCTGTCGGTGGGTAGGGGTCTGGGGGGAGGGATAGCGTTAGGAGAAATACCTAATGTAAATGACAAGTTGATGGGTGCAGCAAACAAACATGGCCCATGTATACCTATGTAACAAACCTGCACGTTCTGCATGTGTACCCCAGAACTTAAAGTATAATAAAAAAAAAAATAATGAAAGGCAAAACTAAAAATAAAATTCAAGTTTCTCTTCCTGGTGAGACATTTTCACTATACCCAATTTGCTCTTGTTAGAGACAGAGGGATTAGAGTTTTCTATAGCAACGACTGTTCTACTAAAGCAGTGTGAGGAGTGTACCATTCAACTATCAGCATGACAGTCAGCCCATGTGTGAAGTGTTCAGGTTAGCTACACCCTGAGACAAGCAGCGTGGACAAGCTGTGACACTTTGAGGAGAGCCACCAAGATGACAGTGGGTGTGAAGCCTATCACATGGGGAACAGCAAAGAGCACTGGAGACATGATCATTGTCTTGAGACATGTGAAGACCCAATCAAATGGGTCTTTTGCTTTTTGCAGATGTTTAGGCAGAGCAGGGGATAGTCTGTCAGCAGGAATGTTCAGAAGGCTTCAGGTATTGGGTGGTAGTTGGACTAGAAGCTTTTTGGTGTCTTAAGATTCTACTGTACCAGTAGTCTTCCTGACTTTGGAGACATCAAGTTGAAAGCTAACAGCGTTTTTTTTTTTTCAGAAGAGATGTATCTTGCTTTGCAAGTTTCCCGTCTTGTGTACTACGGTTTTCCTGTTTTGAATTTCAG
Seq C2 exon
GCTCATTGGTAGATGACGAATCTCTCATTGGTGTACTTCGAACTACCAAGCAGACAGCAGCTGAGGTAAGTGAAAAGTTGCATGTGGCTGCAGAAACTGAGATCAAGATCAACGCGGCTCAGGAGGAGTTCCGGCCCGCAGCCACCCGCGGAAGCATCCTCTACTTCCTCATCACAGAGATGAGCATGGTCAACATCATGTATCAGACGTCATTGGCCCAGTTCTTGAAGTTATTTGACCAGTCCATGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000124721-DNAH8:NM_001371:75
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF127812=AAA_9=FE(15.2=100)
A:
NA
C2:
PF127812=AAA_9=PD(10.0=27.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)