HsaINT0050102 @ hg19
Intron Retention
Gene
ENSG00000007174 | DNAH9
Description
dynein, axonemal, heavy chain 9 [Source:HGNC Symbol;Acc:2953]
Coordinates
chr17:11833183-11835522:+
Coord C1 exon
chr17:11833183-11833410
Coord A exon
chr17:11833411-11835330
Coord C2 exon
chr17:11835331-11835522
Length
1920 bp
Sequences
Splice sites
5' ss Seq
CAGGTACGG
5' ss Score
10.88
3' ss Seq
AAGCGACACTCTCATTTCAGGAC
3' ss Score
6.73
Exon sequences
Seq C1 exon
AACATTCACCTGGTGGCCAAGTGGCTCAGCACCCTGGAGAAGAAGCTGGAGGAGCACAGTGAGAACAGCCACCCAGAGTTCAGGGTCTTCATGAGTGCAGAGCCAGCACCCTCCCCTGAGGGCCACATCATCCCCCAGGGCATCCTGGAGAACTCCATTAAGATCACCAATGAGCCCCCCACGGGCATGCATGCCAACCTGCACAAGGCCCTGGACAACTTCACTCAG
Seq A exon
GTACGGCCCCGGGAGGGAGGCAAAAACAGCAGCACACCTCACAGTCAGCTGATGCAAACTGGTGGGGGGAGAGCATGCAACTCAGAAGGGAGTCGGGTGCTGGTTGGGCTACGGAGCAATGCTGATGTGGGTAAAATGTTCCCACCTGATGCCCACTCAGGGCAACCCCACTCTCCATTGCCAGATAACCCCAGGGGAGTAGAGCTCAGGACATTTCTTTGGCAAGAGATGTGGGGAAGCCTTCTGCAAGTTTACTGTTACCTAATATTCCAAGATGAAGAAGGGCACGTTGTTATACATCTCATTGATAAGATACACTGGGTCACACACTGATGGGCTATCTTCAGGCAGAGAGATGATACTGTCAATCAGATGATATCACTTGACGTCTACATGAATCTTGAGTATCAAGGGTTCAAAGAATCCAGGTGTTAGGTAGTGGGGATATGGATTTGAAATGTAACTGCATGTTAGACCCCCTAAAGTATGGCCCCTGGACCAGCAGCATCAGCATCACCTGGAAACTTGTTAGAAATGCAGATTTTTCTGTCGTCCCAGCTACCTGGGAGGCTGAGGCAAGAGAATGGCGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCGAGATTGTGCCACTGCACTCCAGCCTGGGCGACAGAGTGAGACTCCATCTCCAAAAAAAAAAAAAAAAATTGCAGATTTTTAGGCCCCAATCTGAAACTCTGGGCTGGGGCCCAGGAATCTGTTTTAATGAACCCTCCAGGAGATTCTTATACACAGTCAAGTTTGAGAATACTGTGCTCCAGAGAGACTCAGAATATCAAGTGTTCAAATGCAGACCACTACGTTTCCATTATGGGGAATTTCAAGGCTTATGTTGTAGCGTATTTATTTGAAGCCAGGTCCAAGCCCGTGGTGGCCAACTTTGTATATGAAGTTGTACTGTCAAAGTCTGCGGCCCAGGCCTCTTTGATCTTCTCAAGAAGGCACTATTTCTTTTTGGTTCTCTCTTGGGAGTTCCACCTCCCTGGGCAGGAGAGTACCCAAAGGCCTGAATTGTAGCAGAGTGGAGGCCATCGGATCACCTTAAAATCCATCTGCCACACCACGCCTGGGTGGAATTCAAGGAGAGGGTTCCAGCAGCTGCTAGGGAGGTTTTCTTCTTGGTTGTCATCTTGTCATAGTACCAGTGCATCTCAGGTTTCCCAGAAGCCCTGCCAGCTCACATGTGTCAGATGGGTCATGCAGGTTATTTGAGATGGGCCATCCAACAGGATGACTGTGCCACCTAAACCAACATAAACCTTTGGGGTCTGGTTTAAGCCTAAAGTAAGATGAAGACCATGTAACAGTCAGAGTCTCAGAAGATTTTACTGACTGTGTGACACCCTTGTAGTGTAGGAGTCCAGCAGCCCAACTCTGGGCGGGAAGCTTCCACAAAGATTCAAGGAGCAAAACACATTCAGTACCCCCTGTACTCTTTTTCCCAGCTTAACTCCCAGGCAGTGATTACACCTGCTAAGGTTCCACAACAGGCAAGAAAAGCATGGTAGGAAGGGAAGATATTAGAGATGGTGCCATGGCATGTGCACCCACACCCCACACCCCGGTACATAACATTCTTATTGCATGTCACCCTGATCCCCATCAGCTACATTAGTGAACTTTATTAGCACATCCGTATGCATAAACTTGAACCCTAAACCAAACCCTATTATCACCTGAATCTAAACCTTAATTCAATGCTCAGCTAACCTGACCCTTCCACACGTTCCCCCCAGGCTGTAGTCTCGCTGTAACTCAAACCCAAACCAGAATATATGGTAATGTTTTCCAACACGAACCCTGATTGTAACCTCACCCTAGCCAGCCCCGTATAAGAGAAGTTGTGTGCGAACCTTAAAAGCGACACTCTCATTTCAG
Seq C2 exon
GACACTCTGGAGATGTGTTCTCGGGAGACGGAGTTTAAGAGCATCCTCTTTGCTCTTTGTTACTTCCATGCGGTGGTGGCAGAAAGACGAAAATTTGGGCCCCAGGGATGGAATCGCTCATACCCCTTTAACACTGGAGACCTCACTATCTCTGTGAATGTCCTCTACAACTTCCTGGAGGCCAACGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000007174-DNAH9:NM_001372:63
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.211 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0302810=Dynein_heavy=FE(10.7=100)
A:
NA
C2:
PF0302810=Dynein_heavy=PD(0.6=1.6),PF0302810=Dynein_heavy=FE(14.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAACAGCCACCCAGAGTTCAG
R:
TGGCCTCCAGGAAGTTGTAGA
Band lengths:
350-2270
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)