HsaINT0050627 @ hg19
Intron Retention
Gene
ENSG00000106976 | DNM1
Description
dynamin 1 [Source:HGNC Symbol;Acc:2972]
Coordinates
chr9:130986530-130996386:+
Coord C1 exon
chr9:130986530-130986668
Coord A exon
chr9:130986669-130996299
Coord C2 exon
chr9:130996300-130996386
Length
9631 bp
Sequences
Splice sites
5' ss Seq
AAGGTAACC
5' ss Score
9.24
3' ss Seq
GCCCTCCTGCCCTTCCCCAGCTC
3' ss Score
8.73
Exon sequences
Seq C1 exon
AACGGGGCTGTTTACCCCAGACATGGCCTTTGAGACCATTGTGAAAAAGCAGGTGAAGAAGATCCGAGAACCGTGTCTCAAGTGTGTGGACATGGTTATCTCGGAGCTAATCAGCACCGTTAGACAGTGCACCAAGAAG
Seq A exon
GTAACCCGGAGGCCCGGGCCAGCCCCCACCGCCTCTGCCCCGCCCTGCACTGCTGCCAGGCGCTCCTTCCCCATGTCCCCCCCTGCCTCCTCGGTAGCATGTACAGACCTCAGCGGGGTGGGGAGGCAGGCCACCACTGAATAGGAGACAATGTGCCTCTGAGAGGGCCTCACCCACCCCTGGCCCCCAGGTCTGGGGACCCAGGGATTGGACATGGGTGAGACGGGGATGATGGCTGGCTGTTTACCCCAAGAGCCCACCAAGAGCTCCCCCAGCTCAGAGAATAGGGCTTGAGGGGACCCTGAGCCCCCTCCCTGTCCTCGGAGGTGTCATCTTTGGGAGCTCCAGGGAGGGGTCTGGGGAAACCTTAGCCTTGGAGACAGGTGAAATGCAGGGCCTTCTCGGGCACTGCTCGGTGGGCCTGGGTGGCCAGAGGGGGTGCAGAGGACCCAGGACTAGCAGGTGCCCTGGCTCCCCGCTGTCCTTCATCCTCCCCATACTCATCTCACCCTCACTCAGGACCCTCACACAGGATGCTCACGTAAGACCCTCACTCAGGGCCTCTCCCTCCCTTCCATCCACATCTGGCTTTCCAGGGATAGAGCCCTTCTCCCATCTGCCCCACCATCCAAGCCTCACAGAAGCACGCAGGGAGGCAGGACAGGGAGGACGGTGCCCATTTCACAGCACGAACACTGAAGCTCCAGGAGATCAAGTGGCTTGCCCAAGTCACAGTAGTCAGGAGGTGGCAGAGCTGTTACTTGAAGCCACGGCTCTGGACTCCAAGTCCAGTGCTCCTCGATTCCACCCTCCAGCCTCCCTTCCTTTCCTCTCCCCACTGCTGTCCCGGCCCCTCTCTATCACTACCTCTACTCTTTCTGTCTTTCCTCTTCTCTTTCTGTCTTTTGGTTCCACCAAACCCCTGTGGAGGAGAGGCCAGGAATGCCCCTTGAAGAGAAAGGGAGGGGCGGGACTAGAGCAGGGAGCTGGAGAGGGAGGTCAGGCTGCTATACTGCAACCCTAGGAGGCAGCCTCTGCGCCACGGTTTACGGGAATGGACCCCCCTGGAGTTGTGCAGTGCATGGCCTGGGCAGCTGGATGCGGCAACCCTAGAGATAGGGAATGGTACTGAGGTTTGGAGTCAGGATGAAGCAAATTCTGGGACACTGGGAAACGTAGAATTGAACAGGATGGGTGGATGAGGTCCTGGCCTTGTCCTGGCCTGGGTCAGCTCCTTAGGAGAACCCAAGGCTGTGGACAAAGACGGCACTGGGAGAGAGCAGGCAGCCTCAGTGAGGCCGAGGAGCAGGGGAGCATCCCTGGGAAGAGGATCTGAACTCAATAGGGGTCTTGTACGGAGCAGGGGCTTGGTCCCTCGTACCTCTGGCCATACCTATGGAGCCCAGGGGATGCTTGGCAGCACCTGGGAGGTGCCAACCCCGGGTGGCAAGGGAGGGCCGGTCCCACGCTCACATTGTCTTCTGTTCTCTCTCTCTCTTTATCTGTGTCGATGTCTCTCTCTCTTCCCCCGTGCCCGTGCCATCCTCTCCACCCCTGGATTCCTGTCTCTGCTTGGCTTTCACCCACTTCTCCTCCCCACCCACGGCTGCTCCTCCTCCTGTCCCCACCTCCTCCCCGGGTGCAGGACGGGCCTCTTCACACCTGACCTCGCTTTTGAAGCCACAGTGAAAAAGCAGGTGCAGAAGCTCAAAGAGCCCAGTATCAAGTGTGTGGATATGGTAGTCAGTGAGCTCACAGCCACCATCAGAAAGTGTAGCGAAAAGGTATGACGGCCGCCTGGGCGGGGCTGGGCCTGGCCGTCCATTCCTTGTGGCCACAGCCTCCCGTGGGCAGAAGGATCTGCTGAGCCGGCCTCACGGCTACCCGCAGGGACCCAGCCCTAGTGTTTCCTGCCAGTTTCTAACCCTGGGTACTTGCACTCATGACCCCTCCAGGCCCCCATCCCAGAAGACTTGACTCCAACCCAAGCCTCCTTGGTGGCACCTATGCTAGTGATGAAGATGATGTTAAGGAGATGGCAGCTGTTTACTGAGCACCTACTATGTGCCAAGCACACGCTAAGTGCTTGCCCTTACTATCTGACTCAGTCCTCTCAACCACCCTAAGACGTGGGTAGTGTTGTTATTCCCATTTTGCAGATGGCAAAACAGAGTCTCAGAAAAGAGAAGCAGAGTGTGATTCAGTTTTAGGAAGGACAGAGGAAGGGGTCTGAGGTCAGGGCCTCCTGGGCAGGGGGAGCTGTCCTAGTTCCTCAAAACCAATTTGCCTGAAAGCATATTGGATTACTCACTTTACAGTAATCCGTGCGTGAGAGACAGGGGCGGTCTCTTTTGAGTTGTCTGTGACTTTTTAGATGCCTTTTTCCTATTTGTCTGCTTTTGGGCATTTTGAGGATTTTTAGCCAGGTTGTCTAAAGCAGTTCTTCCCAGGGGAGTGCGAGAGAATCAGTTGCCTGCAGGAGCTTCTCCAGCAGGCTAAATCAGAGGTGCCAGGGGTGAGCCCAGCCTCACCTATATCTGAAGGACTTCCCTATGCTGGTGGGTGGAGGCACATCCACCTTAGCATTGAGTTTCAAATAAGCATCAATCATCTCCATTCCTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAATCTTGCTCTGTCGCCCAGGCTGGAGTGCAGTGGCACCATCTTGGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTATTCTCCTGCCTCAGCCTCCCGGGTGGCTGGGATTACTAGCATGTACCACCACACCTGGCTAATTTTTGTATTTTTAGTAGAGATGGGGTTTTGCCACGTTGGCCAGGCTGGTCTTGAACCCCTGACCGGAGGTGATCCACCTGCCTCGGCCTCCCAAAGTGCTAGGATTACAAACATGAGCCACCGCGCATTCTTTTTTACTGAGCAGTGTGTTGTGTAATCCTTGTATGTTGCTACATAAAGATTGGTCTCATGCCTTTTTTTTTTTTTTTTTTTTTTTTTTGAGACAGTCTCACTCTGTTGCCTAGGCTGGAGTGCAGTGGCACGATCTCAGCTCACTGCAACCTCCACTTCCTGGGTTCAAGTGGTACTTCCACCTCAGCCTCCCAAGTGGCTGGGACTACAGGTGAGCACCACCATGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGCTGGTCTTGAACTCCTGACCTCAGGTGATCTGCCCACCTTGGCCTCTCAAAGTGCTGGGATTACAGGTGTGAGCCACCACGCTCAGCCAGTCTCATGCTCTTTAACTACTGAGTTGTATTCCACTGTAGAAATGTGGCATGATTTATATGTTCAATGTCCTCTTGACGGACATTTAAGTTTCAATTTTTTTTTTTGCCTTCACAAACGATGTTACAATGAACATCCTTATAGATGTATTTGTAGTATTTATCCCATTGTTTTTTCTTTCTTTTTTAGAGACGGGGTTTTGCTGTATCTCCCAGCATGGAGTGCAGTGGCACAATCATAGCTCACTGTAGGCTCAAACTGGGCTCAAGCGATCCTCCCGCCTCAGCCTCCCAAGTAGTGGGACTTCAAGCACTAACCACCACACCCCACCCAGCTAATATTTTTGTTTGTTTGTTTGTTTGTTTTTGGTTTTTTTTGAGACAGAGTTTCACGCTTGTTGCCCAGGCTGGAGTGCAGTGGTGCCATCTCGGCTCACTGCAACCTCCACCTCTCAGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGATTACAGGCTCCTCCCACCACACCCAGCTAATTTTTCTTATTTTCAGTAGAGATGGGGTTTCATAATGTTGGCCAGGCTGGTCTTGAACCCCTGACCTCAAGTGATCCTCCCACCTCAGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCCCTCCTGGCCTAATAATTTTTTTGTTAAGACAGGATCTTACTATGTTGCCCAGGCTGCTCTTGAACTCCAGGCCTCAAGCAGTCCTCCTGCTTCAGCCTCCCAAAATGCTGGGTTTATAGGCATGAGCCACCATCTGGCAACAGTGGCTTCTTGATGGACATTTGGGTTGTTTCCAAATTTTACCATAATCACTGCTTTCCTTTTGGAATGAGAGTCAAAGTGTTTCATGGTTTTTAAATGTTTATATCTAGTAATCAATCTTCTAGGAATCTATCCTAAGGAAACAATCGCAGAGAAAGAAAAGCAAAACTATCCACAGAGATATTCATTGTCAGGTTATTTAGAATATTGAAAAACTGGAAACTATCTGGCCAGGCGCAGTGGCTCACGCCTGTGATCCCAGAACTTTGGAAGGCTGAGGTGGGTGGATCACAAGGTCAGGAGTTCAAGACCAGCCTGACCAATATGGTGAAACCCTGTCTCTACTAAAAATGCAAAAATTAGACGGGCATGGTGGCACGTGCCTGTAGTCCCAGCTACTCAGGAGGCTGAGGGAGGAGAATCGCTTGAACCTGGGAGGTGGAGGTTGCAGTGAACCAAGATCACACCACTGCACTCCAGCCTGGGCGACAGAGCCAGACTCCATCTCAAAAAAAAAAGAAAGAAAGAAAAAGAAAAAGAAAAACTGGAGACTATCTAAATATTCACCAATAGGAAAATGGTTAAGTAAACTGTGATAAATCTATTCAATAGAATATTATGCACCCATTAAAATGTTTATATAGGCTGGGCTCACACCTGTAATCCCAGAACTTTGGGAAGCTGAAGCGGGAGGATTGCTTGAGGCCAGAAGTTTAATACCAGCCTGGGCAACATAGCAAAACCCTGTCTCTACAAAATTTTTTTTTTTAATTAGCCAGGCGTGGCAGTATGCACCTGCAGTCCTTGCTACTTGGGAGGCTGAGGCAGAAGGATGGCTTGAACCAAGGAGTTCAGTTGCACCACTGCACTCCTGGGTTATTTTAGAGACCCTGTCTCTAAAATAAATAAAAAAGAAGTTAGAGACCAGCCTGGGCAACATAGTAAGACCCTGTCTCTACAAAAAATAAAAAGATTAGCTGGGCATGATGGCACACGCCTGTAGTCCCAGCTACTTAGGTGGCTGATGTGGGAGGACTGCTTGAGCCTGGAAGGTCGAGGCTGCAGTGAGCTCTGATTGTGATCACACCACCATATTCCAGACTGGAAGACAGAGCAAAACCTTATCAAAAAAAAAAAAAAAAAAAAAAAGCTTGGCCAGGTGCAGTGGCTCATGCCTGTAATCCCAGTCCAGTACTTTGGGAGGCCGAGGCAGGTGGATCACCTGAGATCAGGAGTTTGAGACCAGTCTCGCCAAATAGTGAAACCCGTCTCTACTAAAAATAGAAAAATTAGCCGGGTGTGGTGGTGGGCACCTGTAATCTCAGCCACTCGGGAGGCTGAGGCAGGAGAATCACTTGAACCTGGAAGGCAGAGGTTGCAGTGAGCCAAGATCACGCCACTGCACTCCAGCCTGGGTGACAGAGCGAGACTCCGTCTCAAAGGAAAAAAAAGGGAGGGTGGGTGGCCAGGCGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGAGTGGATCACGAGGTCAGGAGTTCAAGACCAGCCTGGCCAACATGGTGAAACTCTGTCTCTACTAAAAACACAAAAATTAGCTGGGTGTGGTGGCGGGTGCTTGTAATCCCAGCTACTCGGGAGGCTGAAGCAGAGAATTGCTTGAACCCAGGAGGCGGAGGTTGCAGTTAGCCAAGATTGAGCCATTGCACTCCAGCCTGGGTGACAGATCGAGACTCCGTCTCAAAAAAAAAAAAAGAAAATTAAAAATTAAAAAAAAAGATGGGATTCACTTGTCCCTCCACAGCATATTGTTGGGAAAAAAAAAAAGCAGGTTTCAGAAAAGAACGTATGGTATTTTGGAGAAAAAATAATATATGTGAATGATAAAATCTCAAAGGCGTATTCACCATAGGAATCTTTTTATTTTCTCTTCACAAATTTTATTTATTTATTTATTTCTTTATTTATTTTTATTATTACTATTTTTTTTTTTGAGATGGAGTTTCGCTCTTGTTGCCCAGGCTGGAGTGCAATGGCGCAATCTCGGCTCACTGCAACCTCCGCCATCCAGGTTCAAGCAATTCTTCTGCCTCAGCCTCCCAAGTAACTGGGATTACAGGTGCCCGCCATCACACCCAGCTAATTTTTTGTATTTTTAGTAGAGACGAGGTTTTACCATGTTGGCCACGCTAGTCTCGAACTCCTGACCTCAGGTGATCCACCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAAGCATGAGCCACCGTGCCCAGCCCACTTCATAAATTTTAGTCATGCTCTAATCTTTTACAGTGAGTCTGTGTGATTTCTTTTTCTTTTTTTTGAGACAAAGTCTTGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACGATCTCGGCTCACTGCAACCTCTGCCTCCTGGATTCAAACGATTCTTATGCCTCAGCCTCCTGAGTAGCTGTGATTAAAGGCATGTGCCACCACACCCAGCTAATTTTTGTATTTTTGGTAGAGATGGGATTTCACCATGTTAGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTGATCTGCCTGCCTCGACCTCCCAAAGTGCTGGGATTACAGGCATGCGCCACCATGCCCTGCCGTCTGTGTGATTTTTATGAGCAGAAAAAACTGATCAACAAATATTTGGAAAGGAAAGCTTTGGTCTAAAAGGAGGAAACTGATACTTTTGCCTTTTTTTTTTTTTTTTTTTTTTTTGGAGACAGAATTTCGCTCTTGTTGCCCAGGCTAGAGTGCAACGGCACGATCTCAGCTTACTGCAACCTCCACCTCCTGGGTCCAAGTGATTCTCCTGCCTCAGCCTCCGAGTAGCTGGGATTACAGGCATGTGCCACCACGCCCGGCTACTTTTGTATTTTTAATAGAGACGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCGAACTCCCGACCTCAGGTGATCTGCCCACCTCGGCCTCCCAATGTACTGGGATTACAGGTGCAAGCCACCGCAACCGGCCACTTTTGCCTTTTGATTGGTTTAGTGGATCATAATTATTTTTTTCCTTATAGGCAAAACTCACCTTTGCCTATCTTTGTGTATATATTTTTTCCTCCCCTCGAGTTTTCTAAGGTTATCAAGTCACTCCTGCCAGAAGTTTAATGAGTGTTAATAAGTGAACTCTCATTACTGCCAGCCCTGCTGGGATTAGACTTGCCATCTCTGAGTGAAATGAAGAGTTTAATGTTGGGCATGGGATGTGCTGCTCAGTTCTCTCAACAACTCTAGGAGGGAAGGTGTCATTACTACCCCATTTTCCACATGGAGAAACTGAGGCCCAGAGAGGTCTGGTCATTTTTCTAAGGAGAGTCAGCGGACAGCGGCTGGCTTTGAACCCAGGGCTGAATGGCTCCAGGGGCTGTGTCCCTGACTGCTAACCCGGTGGGCTCCAGGCTGATCGCCCCCTCAGCCAAGGGCTGAGAGGGGAACGTTCCTTTTGAAAAGCTGGCGGAACATCCTGGAAATGTTCAGAGGCAGCCAGAATGGAAAAAGATGCTCAAAGGGGACAGAACTTCTCAAAGGGGTGGAGGCTGCCCTGCCATGGGTGACACGTGGAAAACTTGAGACATGTGACATCCAGGCGGTTAGTGGGAGAATTGGTCATGCTCTTTGGCAAATTGCGCCCTCCTCCTCCCTCCTTCTCCCTGCTCCTCCAAACTCTACCCTGGGAGGGAGCACTTGGGACCACCTCAGAGGAGGCCTGGTGGCTGTGACCCAGTCCCAAATGTCTGCCCAGACTTGGAGACTGCAAAGAGCGGGAGCCCTTCCTTGAGCCTCAGGAGCAGTGGGGTTCACAGGGCCCCTCTAGTCACCGTTTTTAAGCCCCTGGTCTCAGACTGCCCCTCCCTCAGGTCTCCTGAGCTTAGCCACATCATCCACGCCCTTGGCACAGCCACGGGATGATGGGTGTGATGCGGGCATCCCTCGTGTTGGCATCCTGGACCGATATCCAGGGCCCTGCTTTCTCCCCATCCTCCTGCCTCTCCCATGCCCCTCCTCAAAACTCCTTGGCCTCCATCCTGCCCTCAGAATCACCACCTGTGACTCAGGCACACCAATCCCTGGGCCTCTTCCTCCACTGGGGGACCCACCTGAAGGGCCTGACCCAGCCACGGGAAGAAGGACGAGGAGCGCTCCCAGCTTTGCCCCATCGTGCTGCCTGGGCCCCAGGTGGCCACCGCGTGGAGAGGGTGGGCCCACAGGACTGGAGCCCCTGGGGGTGGGCTCCCACCATCAGAAATGCACTGAGTCTCCTCCCCGGAAGAGCTGATCATGGGCCAGAGGGCTGAGGACCCTGTGCCACTCACCCTGGCATCCATCCTTCATTCATTCCCTCATTCTCCAACACGCCCTCTTCCAGCACTGGCCATGGGCCTGGCCCTGCCCCAGCCCTGCCTCGGGGACAGTTGCCACCCAGTTGATTGGAGGAGGTGGAGTGGGAGAGGAGTGGAGAGAGGCCCCTAACTCAGCTCTCAAGCAGTCGGGGCAGGCTTTCTGGAGGAGCTGAAGTCCGGCAGAACCTTGTAGTCAAGTGAATCACCTGGGCTGTGCCCAGAGCCCGACTGAGCTGAGGGCACGATTCGCAGGCAGAGGGGGACGGGTTTGGAGCAACTTCCCCTTCAGCCTCCCTTCATAAGAACTGGGGGGAAAGAGGTGCTGCTGAGCTCCTACCCCAAAGGAGTGGGGTCGAGACAGTGTGGCTGGCCAGAGCCGGGCAGATGTGGCTGGGGATGGTGGTGCCGGGCAGGGGCATGCAAGGGAGACAGAGCTGAATGGATTCCACCAAGAGGGCCAGGGCCCAGCCAGGCCCCGCGGGGTACTGCTCATGCTGCTGGCCCCCGCCTTGCATGTCCCCCAGCCCTCGCATGCTTTTGCTTGTGTTTCCTGCATGTCCTCTGGTGTGACTGCTGGTTTTCCCCTGAACCCCCTCCCCAGCTCTGACAAGGAGCATTGCCTGTCCCAGCCTGACTCAGGAGGCCAACTGGCACCTTGGGCCCTGTCCTCCCCCGATTCCTCCTGGATAGGAATCCAGAGGCTGTCCCCTGCCTGATTCCCCATCTAGCTGTCCCTCCACGCCTTTAGGAAGGCACAGGGTAGCCCTGAGTATGAGGGAACACCTTGGGAGCTAACGGTCCCCAGAGGCCTTAACCTAACCAGTCTGCGGGGCAGGCTCATTCCCATGGCCTTTCTCCCACGGGAACCACCCCTCTGCCCTGAAGTTGCCCAGGTAGGCCAGTGAAGAGGGCCCGGAACCAGGAAGACCCTTGAATCACCATTTGGAACCCACACTTGGGGGAAAGGGGTGGCCGTGGCTTGGTGCCATCAGCGTCCTGGGACCCTAGGTCTCTCTTCCCCGCGTTGTGGGCATTCTGTGTGTGCCTCCCACCCTGCGCCGCGGATCCCTGGACTCGTGGGGTGTGGGTGCTCCCTGCCCGTGCCCTCTGTGTACGTGGCTTTCTGCCCTCCTGCCCTTCCCCAG
Seq C2 exon
CTCCAGCAGTACCCGCGGCTACGGGAGGAGATGGAGCGCATCGTGACCACCCACATCCGGGAGCGCGAGGGCCGCACTAAGGAGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106976-DNM1:NM_004408:10
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.119
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(15.5=100)
A:
NA
C2:
PF0103115=Dynamin_M=FE(9.5=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)