HsaINT0050642 @ hg19
Intron Retention
Gene
ENSG00000106976 | DNM1
Description
dynamin 1 [Source:HGNC Symbol;Acc:2972]
Coordinates
chr9:130982460-130984618:+
Coord C1 exon
chr9:130982460-130982620
Coord A exon
chr9:130982621-130984475
Coord C2 exon
chr9:130984476-130984618
Length
1855 bp
Sequences
Splice sites
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
3' ss Seq
TTCCTCACCCTTACCCCCAGCAA
3' ss Score
6.29
Exon sequences
Seq C1 exon
GCTACATTGGAGTGGTGAACCGGAGCCAGAAGGACATTGATGGCAAGAAGGACATTACCGCCGCCTTGGCTGCTGAACGAAAGTTCTTCCTCTCCCATCCATCTTATCGCCACTTGGCTGACCGTATGGGCACGCCCTACCTGCAGAAGGTCCTCAATCAG
Seq A exon
GTAGGCGACCAAGCCAGGATGGGGCCTGGGGAAACAAGCATGAAAACAGGATAAATTAAGTGTGTTCTGAGAGTGAACAGCAGAGGTTAGCCTCTCCGTAGTGCAGATAGACAAACTGAGCCTCAGAAAAGCAAAGCAACTTGCCCACAGCCCCACAGCTAGGTAGCAGCAAAGCTTCACTGACCTTTCCCTGTCTGGGACCTGCCAGGGAAGCCCTGGAAGTCCCCAACACAGAGAAGGCCAAGACCTATGTGGAGGGTGTCATGGGGAAGAGCTTGGGTTTGGGGGCCAGGATTCAAGTATACTCGGCTGAAGACCTTGACAGGGAATCCCAGGGGCTTCCCCAGGACTTTTCTCCATCTGGAATGGGGCATCCAGAACTGAAGTGCGCGCGCGCGCGCGTGTGTGTGTGTGTGTGTGTGTGTGTCTGTCTGACTGTCTGTCTGTGTAGGCAAGACCTGGTTTCCAATCCCAGTTTTGTCACTCCCCCTCTGAGACACTCTCTCTGGCTCTCTGAGCCTCTATTTCTTTTTTCTTTATTTGTTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTCTTTTCTTTTCTTTCTTTCTTTCCTTTCTTCTTTCTTTCTTTCTCTTTCTTTCTTTCTTTCCCTTCCTTCCTTCCTTCCTTCCTTTCTTTCTCTTTCTTTCTTTCTCTCTTTCTTTCTCTCTTTCTCTCTTTCTTTCTCTCTTTCTCTCTTTCTCTCTTTCTTTCTTTCTCTCTTAGATGGAGTTTTGCTCTTGTCACCCAGGCTGGAGTGCAATGGTGCGATCTCAGCTCACTGCAACCTCTGCCTCCTGGATTCAAGGGATTCTCCTACCTCAGCCTCCCAGGTAGCTGGGATTACAGGCACACACCACCACGCCTGGCTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTAGCCAGGCTGGTCTCGTACTCCTGACATCAGGTGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATAACAGGCATGAGCCATAATCGTGCCTGGCCTCTGAGCCTCTATTTCTGCATCTGTAAAATGGAGACAATGGTGATCAGACCTGTTTCATAGGATTGTTGTAAAGGTTCAGGGAGATACTGTGTGGGGGCACCTAGTGAGCATGAGTGCTAGAACTTGAGAATGACCTTAAAGGAGGCTTTAAACCCAGAGGGTCCAAGGGGCAGCCCTCTGGCCACCCCTGCCTCAGACGCACGTCTAAAAATATTAAATTGGGATGGTATGGTGGTTCATGCCTGTAATCCCACCACTTTGGGAGGCTGAGGCGGGTGGATCACTTGAGGCCAAAAGTTCGACACCAGCCTGGCCAACAAGGCGAAAACCTGTACTAAAAATACAAAAAATTAGCTGGGCATGGTGGTGCACGCCTGTAGTCCCAGTTACTTGGGAGGCTGAGGCAGGAGAATTGCTTGAAACTGGGAGGCAGAGATCGCAGGTTGCAGTGAGCTGAGATCACGCCATTGCACTCCAGCCTGGGTGACGAGTGAAACTCCGTCTCAAAAAAATAATAATAATAAATAAAAATAAAAAGATTAAATTGGCCAAAAATCAGGAAATTCCAAATACAAATCCAGATTTCTGGCTTTATTGAAAATTATGCACTCATTAATTCAACTAATACATCTCTGCAAGCTCCTTCTATGAACCAGTTTTCTTGCTAGTGGCCCGGGCAGCAGTGGCAGGGCTGCCCTCCATAGCTCTCCACCTCACCACGTTCACACAGTCCCCTGGCATCCAAGTCCCTTCCTGGCCCTGTGACCATCTGTCCTCAACCCTTTCCTCACCCTTACCCCCAG
Seq C2 exon
CAACTGACGAACCACATCCGGGACACACTGCCGGGGCTGCGGAACAAGCTGCAGAGCCAGCTACTGTCCATTGAGAAGGAGGTGGAGGAATACAAGAACTTCCGCCCTGATGACCCAGCTCGCAAGACCAAGGCCCTGCTGCA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106976-DNM1:NM_004408:6
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.125
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(17.9=100)
A:
NA
C2:
PF0103115=Dynamin_M=FE(15.9=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCTACATTGGAGTGGTGAACCG
R:
CAGCAGGGCCTTGGTCTTG
Band lengths:
302-2157
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)