HsaINT0050672 @ hg19
Intron Retention
Gene
ENSG00000079805 | DNM2
Description
dynamin 2 [Source:HGNC Symbol;Acc:2974]
Coordinates
chr19:10912964-10916643:+
Coord C1 exon
chr19:10912964-10913034
Coord A exon
chr19:10913035-10916591
Coord C2 exon
chr19:10916592-10916643
Length
3557 bp
Sequences
Splice sites
5' ss Seq
CAAGTAGGT
5' ss Score
7.33
3' ss Seq
TGTCTGTTCTTTGGTTTCAGTGC
3' ss Score
10.29
Exon sequences
Seq C1 exon
ATTCTTCTGCTGATCGACATTGAGCAGTCCTACATCAACACGAACCATGAGGACTTCATCGGGTTTGCCAA
Seq A exon
GTAGGTACTTTTAGAGACTGGCTGGTCGGGCGGCACCAATCCTCACTCTCAGATCCAAGGAGGTGACTGAGTTGGGATTCTCTGAGAGGGCAGGTGTCAGACAGTCTCTGTCGGGGGTCCTGGGGTGAAGGCAGAGCCAACTGAGAATATCTGGAAGCTCTCCTGGGCTGATAGTGGTCCACTGTCCCCAACCAACACGCCTTCTGTGAGGCATCCCCATGGTTAGTTTAGGGAGAGGGCAGTGCTATGTTCAGATCTGCAGGGAGAGGGGGAAGCCAGCCAGCTGCTGCACCCCCTCTCCTTCAGGACTTCTCAGAGCCTTTAGCGACCAGTGTGCAGCTTTTCCCAGACTCTGCCACTTCATGGACAGCATCTCATGGGCTCAGGGCTCCGGAAGCTGCTCTTTGGGAAATGCTGCCTGGGGTCTCCCTAGCTTCAAGGCATACACTGTAGATTTAAACCAGAACCTTCCGTGGCACCCAGATGAGGGCCCACATCGGGGAGCCCTGATTTCAGCAGGATGTCGATTCAGTGTGCGTGGTCTCAGGCATCACCCGCTGATTCCTTCAGCCCCTTGGCATGCTTAGGCCTCACTCAGATTGTTGGAGAGGCTCACGCAGGCCTTCCTGCCTGAGGCAGGCCGGGTGGTGCCGCTGGTATGCCCTCTCGCTGGGCCCTGTGATAGAGCAGTGGGCAAACCCACACCCAGCTCCCCACCCTCAGAGGAAGACCACATGCAGGGAACCGATGGGGACCCAGGGCGTTAAGGTGTAGTGTGCTTAGTGCTGGGCGGGGCCGTGCAGGGCTTGTGGGTGTCCAGAGGGCGGCCACTGGGCCTTGCCTTGAGGGGTCAGGCAGGCTTCCTAGGGGAGGGCCTCTAGAGCCAAATCTCAGGCTATGGAGTCACCAGATACAACATTTATCGGTGCACCTGACAAAGCTGATTGAGGATCTGTTCCGTGCTGGGCACCAGGTAGGTGAGGAGAAGGGAGGAAGGAAAACGAAGGAATGAGGGCCTCATCAGAACCCCTCCTAGAGATGAGCCGAAGTCCCTGACTGGGCCTCCCCTGCCTGTGGGTGGCAGCCCCCGGCCCTGTGCTCCCGGCCGCCGGGTGTGTGTGGGCTCACAGCGCTGGTCCCCATCTTTGGTTTGCTGCTGTTTTCCTCACCTTGATGTCTCTGCTTCTCACACTTCATCCACAGTTCCTTCTCACAATCTCTCCTGTTTTTCCTTTGACCACTCTTTCCTCTGGATTCCTGGGCCTTCCCACTTACCCCAGCTGTTACTATACTGAGCAGCTGGTGACCTGGTGGGTATTGCCTGCTGTGTGCCTTTGCCCTGGTGTGTGAACGGGGTACGCCCTGGCTGGGTGGCCCCAGCCCTGGGTGGGACATCCCTGGGGCCCGCTGAAGAGCTACGGGGTGCTCTCTCAGAGCCAGGGCCAGTGCTGGGCCTCTGGGCCAGGACCTTGACCGCACCAGCTGTAGCCCCTGCTGTTTCAGAGCCTGCAGGCTGGGGAGGTGGAGTCCTTAAACAAATTGTCACAAGGATGATGAGAGTAGGAAGAGAGGGTAGGGGATAGACTATGGGAAAGGGGAGCTGGGAATGTGGCCTGGAGAGATCTTCCTGAAGAAGTCAGGTGATGCCAGGGGGACCCAGAGAATTGGACCCAGGGAAGGAAGGCTACCAGACCAGGCAGGTAGAGGTAAGAGAGCCAGCGGCCAGGCCCCATCGCCAGGAGGGCCCTGCAGGTCCAGGGGAGGATTTTGGATTTTCCCCCAAGACACCAGGATGCTTCTGATTAGATCCAGGCCCAGGAGAGGGGCCACCTTGTGGGCTGCTATTTGAGGGAGCCCTGGCAAGGATGGGAGCCAGGAGGCCCTTAGGAAATAGCACCTCTGGAACCTCACTGTCACCCAGCCATCACTGTGGAGGTTGGCTCAGCTCAGTGCCACCTCCTTCAGATGCTGTTGATGAAAATCCTTCTTGTGCTTGAATGTTCTGGGCTTCCCATTGCCCTCCAAATGTATATTATAAACAGGGCCCAAGCCTGGCGCAGTGGCTCATGCCTGTAATCCCAATACTTTGCAGGAGGCCAAGGTGGGTCGATTGCTGGAGCCCAGGAGTTTGAGACCAGCCTGGGAAACATGGTGAAACCCTGTCTCTACAAAAAATACAAAAATTAACTGGGCATGGTGGTGGTGCGTAATCTCAGCTACTTAGGAGGCTGAGGTGGGAGAATGACCTGAGCCCAGGAAGTCAAGGCTGTGCTGAGCCATGATCACACCAGGGCTCTCCAGCCTGGGTGACAGAGTGAGACTCTGTCTCAAAAATAAATAAGTAAATAAATAGCCCAGATAAGAAGCCCTATAATAAACTTACTGAATGTTGGGAATATCACTGGATAAAATTCTGCCTTTGTTCTTAGTTTTCCAGCCTTTCCTGATCTAGAAACAGAAGCCTACTTTCTCCCTTATCCTACAGCCAACTTGGACTTTAAAACAAAACCCCCGAGGTAGTCAGCAAAGGAAGGTGACCAAGCTGACTTGCTTTTCCATATTGTTCTGAAAGTTTCAGCCAAAGCAATAAGAAAAGACAAGAAAATATGATGGATAAGTAACAGGAGATATATGTTGTTTGCAAGTGGTGATATGATTGTCAGAGTAGAAAATATATTAGAACCGTAAGGTGGTGGAGTAGGTGTCCACATATAAAATATAGTGGGATTTGTCTATGCCGGCATGAACTAGCCAGGAAGTAGGATGGATAAAGAAGAAAAGAGATCTGGGATTGTGGATGAATAAGGAACCTTATAGAAACACACCCTGTCGACCTTGGATGTCCTCTAAATTTGGGTCAGGAGTCATGCAAGATATGTGTCATTTCATGACCAGCAGCTGTCCCACAGTCTGATGTCTAAGACTGGATGGCTCTGTGGTTAGAGCCACTTACAGGCTGGTGTTGGGATCAAATGATGAGAAGAGTAGGAAGAAGGGCCAGGTGCAGTGGCTCATGCCTGTAATGCCAGCACTTTGGGAGGTGGAGCCAGGCAGATCCCTTGAGTCTAGGAATTTAAGACCAGCCTGGGCAACACAGTGAAACCTCGTCTCTACAAAAAATCAAAAATTAGCTGAGCATGGTGGTATGCACCTGTGGTTCCAGCTACTCGGGAGACTGAGGCAGGGGAACTACTTGAGCCCGGGAGGGTCAAGGCTGCAGTGAGCTGTGATTGCGCCACTGCACTCATCTTAGGCAACACCTTCTCACACTTCCCCTTAGAAACTCCGGGATTCTAGTGACATCTGGAAGTAACCTGCGCTTTAGTAAGTCGGCTGAGATGAGGGCCTAGAAGCCTCAATTGAACCAGATACATTTACTTGTTCCGTGTGCCCAGGCCGTTTCCCTTGCGCAGCTCTGTGTGTGCAGGGGGCTTCTCTCTGCCTCTACCTGTGGCTGCTCACTTGGTCCCCAGGGAGAGAACGGCCACATTCGCCTCTTCCCCTTCTTCCCCCCCGGCATCTTGTCCACGTGAACCCTGTCTGTTCTTTGGTTTCAG
Seq C2 exon
TGCCCAGCAGAGGAGCACGCAGCTGAACAAGAAGAGAGCCATCCCCAATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000079805-DNM2:NM_001190716:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.071
Domain overlap (PFAM):
C1:
PF0103115=Dynamin_M=FE(19.3=100)
A:
NA
C2:
PF0103115=Dynamin_M=PD(10.1=66.7)
Main Inclusion Isoform:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)