HsaINT0051463 @ hg19
Intron Retention
Gene
ENSG00000146094 | DOK3
Description
docking protein 3 [Source:HGNC Symbol;Acc:24583]
Coordinates
chr5:176936476-176936858:-
Coord C1 exon
chr5:176936803-176936858
Coord A exon
chr5:176936659-176936802
Coord C2 exon
chr5:176936476-176936658
Length
144 bp
Sequences
Splice sites
5' ss Seq
CAGGTGCGT
5' ss Score
9.73
3' ss Seq
CCCCTCCCCCCGGCCTGCAGCTG
3' ss Score
8.9
Exon sequences
Seq C1 exon
AACTCATGACTCGGGGAGCCAGACTGCGATCAGACGCGCGTGCCCAGCTGAACCAG
Seq A exon
GTGCGTGAGAAGGCTGCCTTCAGGTGGCCGGGGGCTCCCTCCAGGTAGGTGTGGGCACCTTGGGCAGCCAGAACCCCAGGGAGGAAATACATGCTGCCCCCAGCCCCTGAGCTGAAGACAGGCTCCCCTCCCCCCGGCCTGCAG
Seq C2 exon
CTGTCTCTAGACGGAGGGACGGGAAGTGGCCAGAAGGGGAAGTGTGAGGAGTTCCCGTCCAGCCTGTCATCAGTCTCCCCAGGTCTTGAAGCGGCGGCCCTGCTCCTGGCCGTGACCATGGACCCTCTGGAGACCCCTATCAAGGATGGCATCCTCTACCAGCAGCATGTCAAGTTTGGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146094-DOK3:NM_024872:1
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.059 A=NA C2=0.118
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACTCATGACTCGGGGAGCC
R:
GCCAAACTTGACATGCTGCTG
Band lengths:
236-380
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)