HsaINT0051464 @ hg19
Intron Retention
Gene
ENSG00000146094 | DOK3
Description
docking protein 3 [Source:HGNC Symbol;Acc:24583]
Coordinates
chr5:176932012-176935543:-
Coord C1 exon
chr5:176935238-176935543
Coord A exon
chr5:176932112-176935237
Coord C2 exon
chr5:176932012-176932111
Length
3126 bp
Sequences
Splice sites
5' ss Seq
CCGGTGAGT
5' ss Score
10.9
3' ss Seq
GACTTGAACTCATTCCCCAGGGG
3' ss Score
7.23
Exon sequences
Seq C1 exon
AAGTGCTGGCGGAAGGTGTGGGCTCTGCTGTATGCAGGAGGCCCATCAGGCGTGGCACGGCTGGAGAGCTGGGAGGTCCGGGATGGTGGCCTGGGAGCAGCGGGTGACAGGTCGGCAGGGCCTGGCCGGCGAGGGGAGCGACGGGTCATCCGCCTGGCTGACTGTGTGTCCGTGCTGCCGGCTGACGGCGAGAGCTGCCCCCGGGACACCGGTGCCTTCCTGCTCACCACCACCGAGCGAAGCCATCTACTGGCTGCTCAGCACCGCCAGGCCTGGATGGGCCCCATCTGCCAGCTGGCCTTCCCG
Seq A exon
GTGAGTGCGGCGAGCAGGGGGGCGATTGGGCTGGGGCACCTGCCCCCGACTTGTCCACCTCCACGCTCACATCCCATCACCCAGCAAGCTCCACCGAGCACCTACAAGCCTGGGAAAAGTAAATCTATAATGACTCTCAGAGGGCCGTGCGTGCCATGGAGAAAATGGACCGCCAGGGGAGCAGGAGGAAGTGAGGGAGCGACGGGCAGGGTGGCCAGGGAAGGCCTCTCAGAGGAGGGCCCTGAATGACAGGAACCCACTGGGCAAAGGTCTGAGGACAGGGGCAGCCTGGGGAGTTGTGAACAGAGGGAGTCCCGTGGGCAGAGGCCCCGAGGCCGGACAGTGTGGGGTGTTTAAGGGCAGAAAGAAGGCGACGTGGCTGGAAGGAAAGGAGTGCAGGAGGAAGCCAACTCACAGAGCTTAGGAGAGCGGCTGAAATGCCCTAGGCCATGTGTGTGGTTTTGTTCTGAGTGAGAGGCGAAGGCTTTGGAGGGTTTAAGCCGGACATGTTTGTAAAGCCCCAAAAGGTCTGTGATGGGTCAAAAGGAAGTGAGCCTGGGGGTTCTTCAAAGAGGTAAACAGAGTTACCATGTGGCCCACAGGTCCACTCCTAGGTGTGTGCCCAAGAGAACTTGAACAGGTGTTCAAACAAAACATGTACATGTGAGGCAGGAGGATCGCATGAGCCCCAGAGGTCGAGGCTGCAGTGAGCTGTAATCGTGCCACTTCACTCCAGCCCGGGAGACAGAGCAAGACCCTATCTTAAAAAAAAACCCACATGGACATGAACGTCCATAGCAGCACTACTCACAGCCACCAGAAGGTGGAAACAGCCTACATGGCCATCAGCTGACAAATGGATAAGCAAAACGTGGTCCGTCCGCAAGATGGAATACTACTCAGCCATAAAAACAAACAAACGCCTGGCACAGTAGCTCTTGCCTGTAATCTTAGCACTTTGGGAGGCTGAGGTAGGAGGATTGCTTGAGCCTAGGAATTCAAGATCAGCCTGGGCAACATAGTGAGACCCTGTCTCAAAAAAAAAAAAGAAAAGAAGAAAGAAAGAAATGTACAGACAAGGTAACTCCATTGGGATAGAAATCAGATGAGTGTTGGCAGGAGCTGGAGGAAGGGAGAAGTGGGGAGTGGCTGCTCATGGGTACAGGGCTTCCATGTGGGATGATGGAAAAGTTCTGGAACTAGACAGTGGCAACAGTGCACAGCCTTGTGAGTATACTAAAAAGCACTGGTGGCCGGGTGCGGTGGCTCAGGCCTATAATCCCAGCACTTTGGGAGGCCGAGGCGGGCGGATCACCTGAGGTCAGAAGTTCGAGACCAGCCTCAACATGGAGAAACCCCGTCTCTACTAAAAATACAGAAGTAGCTGGGCATGGTGGTGCATGCCTGTAATGCCAGCTACTCGGGAGGCTGAGGCAGGCAGAATTGCTTGAACCTGGGAGGCAGAGGTTGCGGTGAGCCGAGATCATGCCATTGCACTCCAGCCTGGGCAACGAGAGCAAAACTCCGTCTCAAAAAAAAAAAAAAAAAAAAGAAAAGAAAAAAAAGAGCACTGATGATACACTTTAAGATGTAAAATGGGCCGGGCGTAGTGGTTCACACCTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATTACCTGAGGTCAGGAGTTCGAGACCAGCCTGGCCAACATGGTGAAACCCTATCTCTACTAAAAAAAAATTACAAAAATTAGCTGGGTGTGGTGGCACACGCCTGTAATCCCAGCTACTACTTGAGAGGCTGAGGCAGCAGAATTGCTTGAGTCTGGGAGGCAGAGGTTGCAGTGAGCTTAGATCGCACCACTGCATTCCAGCCTGGCCGACAGAGCAAGACTTTGTCTCAAAAAAAAAAAAAAAAGTAAGATGGTTAAAACAGTAAATTTTATGTTCTCTGTATTTTATCATATTTTAAAAATCAAAAAACAAAAGGCAGTTGAGGTTAGGCATGGAGGTTCGTGCCTGTAATCCCAGCACTTTGGGAAGCCGAAGCACGTGGATCACCTGAGGTCAGGAGTTCGAGACCAGCCTGCCCAATATGGTAAAACCCTGTCTCTACTAAAAATACAAAAAATTAGCCAGGCATGGTGGTGGGCACCTGTAATCCCAGCTACTTGGGAGACTGAGGCAGGAGAATCACTTAAACCCGGGAGGCGGGCTGGGCGCGGTGGCTCATGCCTGTAATCCCAGCACTTTGGGAGGCCGAGACAGGCGGATCATGAGGTCAGGAGATCGAGATCATCCTGGCTAACATGGTGAAACCCCATCTCTACTAAAAATACAAAAAAAATTAGCCAGGCCTGGTGGCGGGCACCTGTAGTCCCAGCTACTTGGGAGGCTGAGGCAGGAGAATGGCGTGAACCTGGGAGGCGGAGCTTGCAGTGAGCCAAGATCGCGCCACTGCACTCCAGCCTGGGCGACAAGAGTGAGACTCCATCTTAAAGAAAAAAAACAAACCCGGGAGGCGGAAATTGCAGTCAGCCGAGATCTCGCCATTGCACTCAAGTATGGGTGACAGAGCAAGACTCCATGTCAAAAAAAAAGGCAGTTGACAGGAGCAAGGAGCCTGGTGAGGAAGCTGTGGCATTTGACCCGGCTGTGTTGCTATGGGCCAGGGTGGTGCTAGTAGAGGAGCTGAGTGGGAAAGAGCACAGGGGACATGCTGAAGGCCTGGGTGTGGGGATGAGGCAGAGATTGGGGGCACCTTGCAGGGTCATAGCAGGTGGCTGTGGTGAGATGGAGGAAGACACCTGGGGTACTGCTCTAGGCTGTCAGACATACAGAAGCTGGCCCAGCCAAGCCCAGGGGCTGCAAGGGACATCCTTTTGTGTCCCCAGTGATCTGCAGCTCTCAGACACCCTCAAGCACAGTGCCTCTTGCCCAGCCCAGCACTCTCAGTGGGGAGCCAGGTGGGAGAACAGGCTCGGAAGGGGACCTAGGCTTATGCAGCGAGCCGGGCAAAGCTGGAACTGGAGCCCAGGCCCCTGGATGCCCCCTGGCTTGTGGAGTTCTGGGATACTGAGGGGAGGGGACAGGGCATGGGAGTGCGGTGCTCTCACCTTTGACTTGAACTCATTCCCCAG
Seq C2 exon
GGGACAGGGGAGGCCTCCTCAGGATCCACAGATGCCCAGTCTCCCAAGAGGGGCCTGGTCCCCATGGAGGAAAACTCCATCTACTCCTCCTGGCAGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000146094-DOK3:NM_024872:3
Average complexity
IR-C
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.158 A=NA C2=0.520
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
PF0217412=IRS=PU(1.6=2.9)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)