HsaINT0052428 @ hg19
Intron Retention
Gene
ENSG00000046604 | DSG2
Description
desmoglein 2 [Source:HGNC Symbol;Acc:3049]
Coordinates
chr18:29118714-29121277:+
Coord C1 exon
chr18:29118714-29118941
Coord A exon
chr18:29118942-29121155
Coord C2 exon
chr18:29121156-29121277
Length
2214 bp
Sequences
Splice sites
5' ss Seq
TATGTAAGT
5' ss Score
6.69
3' ss Seq
TCAATTTTGTGTCTGTACAGTGG
3' ss Score
7.07
Exon sequences
Seq C1 exon
GTACCAGTGTGCTGCTGCAACAAAGTGAGAAAAAGCTTGGGAGAAGTGAAATTCAGTTCCTGATTTCAGACAATCAGGGTTTTAGTTGTCCTGAAAAGCAGGTCCTTACACTCACAGTTTGTGAGTGTCTGCATGGCAGCGGCTGCAGGGAAGCACAGCATGACTCCTATGTGGGCCTGGGACCCGCAGCAATTGCGCTCATGATTTTGGCCTTTCTGCTCCTGCTAT
Seq A exon
GTAAGTCTTTAAAAGCCACTCTGTTGTGCTTTTGGGAATCTGAGTGCACTCCTGGAGATGTGTTACTATGGTAGTCATTGATTTCTTCACAGTTATTCTTTAACCACACTAGAGCACTTTGAGGGTGAATAGGGAAACAACTGATGATTGGCAAATCACCAAAGCATAATATAAGACTCTTCAGAATTTTGTTTTATAAATGTATATCCTTTTCTGGTTTCAGTAACTTAGGAACTATTGGCATAAACTTCACTGGTATTCCCATTTTGATGAGCTCTGTGAGGGCAGCATGCTGTCTGTTCTCTTCACTGCTGTATTCCCAGTGTGTGGAACAGAGCCTTGCATGTAGTAAGCGCTCAAAAAAGATGTGTTGCATGACTTTGGGTTATGGGCACAAGGTTTTTTACAAACCCAGTTTATTCCAATCAATCCTGCTTTGTACATTCAACTTATCAGAGCTCCGCCTCCCTGATATTCCCCGCTTGCCTTGTTTCTTCGTCAGCACCAAAAGTAGGCAGACCCTCTGAGCACTTCCTGTCCTTCCTGACCGTAAGATGTTCTCAACCAGTCCTGCCTGCCCTACCCACGCTCCAAAGACCTCGGGTTTCCTTTTATAAAAGAACAAGGGACTGCATCCTGAGGTCACATGAAATATCACTCTACTTGACCACTGAATATGGACAGAGGGCCGCCTCCAAGGCAGCCTAGGCTAGTGCAGTGACAGAGGAGAGGTCTGTTAGACAAGGGGTCCCCAACCCCCAGGCTACAGACCAGCACCTGTCCATGGCCTGTTAGGAACCAGGCCGCACAGCAGGAGGTGAGTGGTGGAAGAGTGAGTGAAGCTTCATCTGTATTTACAGCCACTCCCCATCACTCGTGTTACCACCTGAGCTCTACCTCCTGTTAGACCAGTGCTGGCATTCGATTCTTATAGGAGCTCAAACTCTATCGTGAACTACTCATGCCAAGAGATCCAGGTTGCGTGCTCCTTATGAGAATCTAATGCCTGATGACCTGTCACTGTCTCCCATCACCCCCAGATGGGACCATCTAGTTGCAGAAAAATAAGTTCAGGGCTCCCACTGATTCTACATTATGGTGAGTTGTATAATTATTTCATTATATATTACAATGTAATAATAATAGAAATAAAGTACACAATAAATGTAATGCACTTGAGTCATCCCAAAACCAACCCCCCTACCCCTAACTTCCCTGTGGAAAAACTGTCTTCCATGAAACCAGTCCCTGGTGTCAAAAAGGTTGGGGACTGCTGTATTAGAGCCATTGGTAGATGTGCAATTGAAAGCACAGCACTCAACAGTCTGCAGTGTACTTTTATACCATCATCTCCATGCTATGGCTACATATACAGATACATAACGGTAAATGACTTGTCTCAGCTTACCAAGTTTGTAGGTAGGTACTGGAGCTGGGACTGTATCTTTTGCTCAGGGATTCCTTGCACTGCTTTCTCATCTCAGATTCCCTGGAGCCTAATGTGGTACTTGGCACATAATAGACACTTGATGAATGTTTGTTAAAATTGTTGAATTGCCACTGGCTGATTTCAGTCTTCTTATTAATCGTAGTAGCTGTAGTTAATGTGCTGTTGACTGTTTGACATAAAAACGAATCTAGGCAGTAGCCAGTTCATCATTGGAAGCTGCCAAATGGGAGTGGCAGATGGGCATGCAGGTGTGTTTAATTCTTTACTACATTGATCAAGGGGTCAGCCTTGGTCTTTGCTTCCTCCTAGGGGTAAAATAAAATCTAAGAAGAGGGCTCTGAAATTGTTATATGTTTCACTTTATTATTTCTAATTACTGTTTTCAATAGTACATATATTTTTGCAACAGTGATTTTTTTTTAATTGGACCATAGTTTTAAAAAAATTAATCTTTAAGCTGGTTTTGATGATTTGGATACTATCTGAACCTAGTCTTGGTATTCCACTCAGCAGCCACAGACAGCCTCTTTTTGATGAACAAGGCCTTGAATCTGTAAGACTCCCTCATCCTGCCTTCGGGTTTTGGAGTAATTCACCCAAAACAAGCTTGGTAAGGTTGGATCAGGGTGAAGAAAAGAAAAATAGAGCTGTAAATAAGTGAAGACAAGTCCAGGAAGGGACATGCAAATTCCAAAATTGTGCAATATAAATTTAGAAATATATCAAGGTTAACCTTATCTGTGTTCAATTTTGTGTCTGTACAG
Seq C2 exon
TGGTACCACTTTTACTGCTGATGTGCCATTGCGGAAAGGGCGCCAAAGGCTTTACCCCCATACCTGGCACCATAGAGATGCTGCATCCTTGGAATAATGAAGGAGCACCACCTGAAGACAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000046604-DSG2:NM_001943:12
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.317
Domain overlap (PFAM):
C1:
NO
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)