HsaINT0056585 @ hg38
Intron Retention
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]
Coordinates
chr22:41157169-41158500:+
Coord C1 exon
chr22:41157169-41157408
Coord A exon
chr22:41157409-41158411
Coord C2 exon
chr22:41158412-41158500
Length
1003 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGA
5' ss Score
10.57
3' ss Seq
ACAAATGGTTTCTTTTGCAGTTG
3' ss Score
8.74
Exon sequences
Seq C1 exon
GATTACTTTGATATTGTGAAGAGCCCCATGGATCTTTCTACCATTAAGAGGAAGTTAGACACTGGACAGTATCAGGAGCCCTGGCAGTATGTCGATGATATTTGGCTTATGTTCAATAATGCCTGGTTATATAACCGGAAAACATCACGGGTATACAAATACTGCTCCAAGCTCTCTGAGGTCTTTGAACAAGAAATTGACCCAGTGATGCAAAGCCTTGGATACTGTTGTGGCAGAAAG
Seq A exon
GTAAGAAATGTGTTTCAGATTTGACTTTAACTTTTCTGGGATACCTAGAATAATATAGTGGTGACTGGGATAAGAGAATATCCTGCTTCTGGCTTTGACATGGCTTTTTTTTTTTTTTTTTTTTTTCCTTTTTGACAGGGTCTTATTCTCCCAGGCTGGAGTGCAGTGGTGAGGTCATAGCTCACTGCAGCTTCAACCTCCTGGGCTCAAGCAATTCTCCCACCTCAGCCTCCTGAGCAGCTGGGACTACAGCCGTACGCCACCATGCCTGGCTGATTTTTTAAATTTGTTTTGTAGAAACAGGGTCTCATGATGTTGCTCAGGCTAGTCTTGAACTCCTGGGCTCAAGCAGTCCTCCTGCCTCGGCCTCCCAAAGTGCTGGAATTACAGTCATGAGCCACCTCTCCCAGCCAACACAGTCTTTCTCTTACTGTGTGCCACAGTAGTAATATCTCTTAATATGAAATGGGCTTTCTTTAAAGGCATTTTTTCAGAGTGGCAATTGTATGGAAAAGTTGACTAATTAAATAATCAACAGACTGTTAACTCATCTGGAGTAGGGGCATTCTTATATTCACCTGTGGGTGCAGATTCCTCAGCATGTGCTGGCTTTCCTGTACATACCAATTCACATTATTGGTTTTTTGTTTTTAAAATAAGACTATGGTCTTGCTGTGTTGCCTAAGCTGGTCTGGAACTCTTGGGCTCACGCAGTCTTCCCACCTCAGCTTCTGAGCACTGCAGGCATGTGCCACCCTGCCCAGCTATTCCTGTTAGGTTCTTTGGTAAAGTGATGGAAGGATATGACTGCTAAGCCTACCTCAGCGTTTTGAAATAATGTGGTAGTAAACTGAGAATGATTTTCAGGAACTGAATTAGCCCATCATTATTAACATAAATGAGAACTAAGACACCACTGACTTCTGTTTCTGACTTGCCATTCTTACTGTTCTAGCTTGTCCTTAAGGCCTCTGTGCTTTTTAACAAATGGTTTCTTTTGCAG
Seq C2 exon
TTGGAGTTCTCTCCACAGACACTGTGTTGCTACGGCAAACAGTTGTGCACAATACCTCGTGATGCCACTTATTACAGTTACCAGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393:ENST00000263253:18
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.013 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=PD(64.4=70.0),PF060018=DUF902=PU(28.6=15.0)
A:
NA
C2:
PF060018=DUF902=PD(66.7=93.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTACTTTGATATTGTGAAGAGCCCCA
R:
TGTTCTGGTAACTGTAATAAGTGGCA
Band lengths:
326-1329
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development