HsaINT0059132 @ hg38
Intron Retention
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177403859-177404413:-
Coord C1 exon
chr5:177404196-177404413
Coord A exon
chr5:177404091-177404195
Coord C2 exon
chr5:177403859-177404090
Length
105 bp
Sequences
Splice sites
5' ss Seq
GAGGTTAGG
5' ss Score
4.36
3' ss Seq
CAGCCCCTGCTCCTCCACAGCCT
3' ss Score
6.13
Exon sequences
Seq C1 exon
GAACCCGGACAACGACATCCGCCCGTGGTGCTTCGTGCTGAACCGCGACCGGCTGAGCTGGGAGTACTGCGACCTGGCACAGTGCCAGACCCCAACCCAGGCGGCGCCTCCGACCCCGGTGTCCCCTAGGCTTCATGTCCCACTCATGCCCGCGCAGCCGGCACCGCCGAAGCCTCAGCCCACGACCCGGACCCCGCCTCAGTCCCAGACCCCGGGAG
Seq A exon
GTTAGGAAGTGGGGGGGGGAAGGAGGAGCCGAGAGGGCGCCGGGCGAGCTAGATTCCGGCCAGCCGGCCGCGGGCTCTCCGTCCTCAGCCCCTGCTCCTCCACAG
Seq C2 exon
CCTTGCCGGCGAAGCGGGAGCAGCCGCCTTCCCTGACCAGGAACGGCCCACTGAGCTGCGGGCAGCGGCTCCGCAAGAGTCTGTCTTCGATGACCCGCGTCGTTGGCGGGCTGGTGGCGCTACGCGGGGCGCACCCCTACATCGCCGCGCTGTACTGGGGCCACAGTTTCTGCGCCGGCAGCCTCATCGCCCCCTGCTGGGTGCTGACGGCCGCTCACTGCCTGCAGGACCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187:ENST00000253496:9
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.554 A=NA C2=0.218
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PD(35.4=37.8)
A:
NA
C2:
PF0008921=Trypsin=PU(18.6=56.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTCATGTCCCACTCATGCCC
R:
GAAACTGTGGCCCCAGTACAG
Band lengths:
258-363
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development