HsaINT0059166 @ hg38
Intron Retention
Gene
ENSG00000180210 | F2
Description
coagulation factor II, thrombin [Source:HGNC Symbol;Acc:HGNC:3535]
Coordinates
chr11:46723180-46723518:+
Coord C1 exon
chr11:46723180-46723285
Coord A exon
chr11:46723286-46723381
Coord C2 exon
chr11:46723382-46723518
Length
96 bp
Sequences
Splice sites
5' ss Seq
TGAGTGAGT
5' ss Score
6.51
3' ss Seq
TGGGCAATTTCCTGTTCCAGAAT
3' ss Score
6.68
Exon sequences
Seq C1 exon
GTAACTGTGCTGAGGGTCTGGGTACGAACTACCGAGGGCATGTGAACATCACCCGGTCAGGCATTGAGTGCCAGCTATGGAGGAGTCGCTACCCACATAAGCCTGA
Seq A exon
GTGAGTGAGGGGCCGGCCTTCCCACCATGGGCTGAGAACAGGGAGCAAGCGTACCTCAAGCCCAACAGCCTCCTGTTGGGCAATTTCCTGTTCCAG
Seq C2 exon
AATCAACTCCACTACCCATCCTGGGGCCGACCTACAGGAGAATTTCTGCCGCAACCCCGACAGCAGCACCACGGGACCCTGGTGCTACACTACAGACCCCACCGTGAGGAGGCAGGAATGCAGCATCCCTGTCTGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000180210:ENST00000311907:5
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.056 A=NA C2=0.447
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PU(41.8=91.7)
A:
NA
C2:
PF0005113=Kringle=PD(57.0=95.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TACGAACTACCGAGGGCATGT
R:
TGTAGTGTAGCACCAGGGTCC
Band lengths:
178-274
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development