HsaINT0063042 @ hg19
Intron Retention
Gene
ENSG00000119402 | FBXW2
Description
F-box and WD repeat domain containing 2 [Source:HGNC Symbol;Acc:13608]
Coordinates
chr9:123538371-123540823:-
Coord C1 exon
chr9:123540629-123540823
Coord A exon
chr9:123538505-123540628
Coord C2 exon
chr9:123538371-123538504
Length
2124 bp
Sequences
Splice sites
5' ss Seq
CGGGTGGGT
5' ss Score
6.14
3' ss Seq
TGTGTAATTATATGCACTAGTAT
3' ss Score
1.51
Exon sequences
Seq C1 exon
GGTCAGATGACTTGTCTGCAAAGCTGTGGGATGTGAGCACAGGGCAGTGCGTTTATGGCATCCAGACCCACACTTGTGCAGCGGTGAAGTTTGATGAACAGAAGCTTGTGACAGGCTCCTTTGACAACACTGTGGCTTGCTGGGAATGGAGTTCCGGAGCCAGGACCCAGCACTTTCGGGGGCACACGGGGGCGG
Seq A exon
GTGGGTTGCCCTTTTTCAAGGGTTTTTACAACTTAGCCTCATCCTTTTAAGCCAGGAGCCAAGAATGTGAAATGCTTTTTTTTTTTTAATTTAACCTGCTTTTTTCAACCCTCTTTCTTAGTCATTGCAGTTATTTCCCTTTATTCTAGTTACTCTTATTTCGAATGTTTTACCCAGTTTTGCTTTTTCTTGCTTTCTTCTATGTGTGTACCCTTCTGGTGGGAAGGGTAGTTTTCATTCTCTCTCTGTTTCTCTCTCTCTCTCTCATTCTCTCTCTCCCCCCTCCTGTTTCATTTATATCCTATTGAACAGACAGTCCCTTGGCTTTTATCAGATTCCATACCTCTGAACTGAGTAAATCCTACTTGTGTAAATTCCACTTTATTTGTAGCATTAGGGCTGAAAGTTCTTTGGTGTGACGGTGGTTCTTAGATTGTGTGGTCTACACAGATTACATCCAGTTTGAGCTTGGTTGACAGTTGATTAAAACAAGCTACCACCTAGAGATAAGGCGAAAGAAACATACCTGAATGTTTCCTAATAAATGTATAGCATCCTTATTTTGCAAAAACTGGTCATTTGAATATAGCCTTGAGATTTGAGCTTCTCTCTCTGTTGCTTTTTTTTTGGCGGGGGCGGGGGTGGGGAGGCTTTGTGTAGAAATTGAGCTATTTCCCAGCCTCTTGTGTTGAGCAGCTCCCTTCCTTTCCCCCATTTACCCACTGCTTTAGCCTCTGAGAATCATAGTCTGTAATGTCAAGCATTACGTTTATGAGCAGCCTTCCAAAACTCCCTTAACAGGTTGCGTCCCTCTATTTCCCAGTAACTTGTATTACTGTAGACCGCTCATCATACAAATATAATCTTGCTTCCCCACCAGACTAAACTCCATAAGGACAGTGATCTTATCTGTCTTGTTCACCCATGTGACTGGAGTTACTTGCACTGTACCTGGTGCTTAGTGATTCTTTGAAGTAAAACTAGCCGTTAGGCTAATAAAAACACGTATTTTTTGCTTCATTTTATTTGTCCTCCTATATACTCTTCTTCAGTCTTTGCTGTCTGCTACCACTTGTTAGAAATTAATATTTGAAGGTGCATGTATGCATGGAAGTATATGTTAAATTGAGTGTTATGTTCCACAATGTTAAGATGTACCATGACTTCCAGGTGATTTTATTCCTGATCAACTTTGAGAACCCTGCTCTAAAAATTTTTATTACTGTTGCCTAGACATTGCTGAGGTTTTTCTTAACTTCATACCTTTACTATTCCCTCTGCTTGCAGTATTCTTTTTTCTTTCCTTGATAAACTCTGCTCATCCTTTAGGGCCCATCTCCAATATCGCCTCTTCCCTGAAGTCCTCCCTGATACCCCTGGGCAGAGTTAGTCATTCTCCTTGATGTTTCCCTAGCAAGAGGTAAACATTTATTTTTTTCTGGGCTTCCTCCTCCACTCCCTACTTAGATTGAGTTCCTTAAAGGAAGAATCAGTGTCTTCATCTCTGGGTCCCTAATGTTCCTTTAGAACTGGTATACATTTGAAAACAAATATTTGAGTACACACTATACAGCTTACACTGTTTTTGGCGCTGGGGATACAGCTGTGAAGAAATTCAGACACTTTTGAGTTAATGGCTTAATCTAACCTTTGAGATCCTTGTTTTTGTTTTGTTTTTTCTCTCTTTACATTGGGTTTTCTTGAGTCTGGGTGCTGTTTTGCAGCTTCCATTCTTTATATTTTGTCTTACTGTTAGTGTGTATCAGAGTAGGACCATGTACGTTTTGTTTTCCTGCATAAATTAGATAAAGTATTGTGTAGTGTCAGGCAGGCAGTCCTAAGAAGGAATGCCATTATCTCCAACATTTGTTTTGCCTCTCACTGTAGCTACCACAAATAAAAGAGATTGTATTATTCCTAGGACTTTCCACCTTAGAATAATAAGCTATAATAGTAAGAATTTTGAAATAGTTTTATCAGAAAATTGCTAGTTGAATAGCATCATTCTTACGGTGTCTCTGGTTGGGAAATTATATAATTGGGGAAAATAAACATTATTGAACTCTATTATAAAAGACCCACTGACAGAGACATGTTTTAACTTTGTGTAATTATATGCACTAG
Seq C2 exon
TATTTAGCGTGGACTACAATGATGAACTGGATATCTTGGTGAGCGGCTCTGCAGACTTCACTGTGAAAGTATGGGCTTTATCTGCTGGGACATGCCTGAACACACTCACCGGGCACACGGAATGGGTCACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000119402-FBXW2:NM_012164:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PD(28.6=15.2),PF0040027=WD40=WD(100=53.0),PF0040027=WD40=PU(33.3=19.7)
A:
NA
C2:
PF0040027=WD40=PD(64.1=55.6),PF0040027=WD40=PU(31.9=33.3)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)