MmuINT1010197 @ mm10
Intron Retention
Gene
ENSMUSG00000035949 | Fbxw2
Description
F-box and WD-40 domain protein 2 [Source:MGI Symbol;Acc:MGI:1353435]
Coordinates
chr2:34810983-34813009:-
Coord C1 exon
chr2:34812815-34813009
Coord A exon
chr2:34811117-34812814
Coord C2 exon
chr2:34810983-34811116
Length
1698 bp
Sequences
Splice sites
5' ss Seq
CGGGTGTGT
5' ss Score
5.31
3' ss Seq
CTTTATGTTGTATGCACTAGTGT
3' ss Score
4.88
Exon sequences
Seq C1 exon
GGTCAGATGACTTGTCTGCAAAGCTGTGGGATGTAAGCACAGGGCAGTGTGTTTACGGCATCCAGACCCACACTTGTGCAGCTGTGAAGTTCGATGAACAGAAGCTTGTGACAGGCTCCTTTGACAACACTGTGGCCTGCTGGGAGTGGAGTTCCGGAGCCAGGACCCAGCACTTCCGGGGGCACACGGGGGCGG
Seq A exon
GTGTGTTCTCCTTTTTCAAGAATCTTTACAGTTACTTTAGCCATGCCTTGTAAGACTAAGAGTCAAATATTTAAGGTGGTTTTTTGTTTGTTTGTTCTTTTGGGGGGGGGTGGCGGCTTGCTTACTTGCTTTTAATCTAGCATTTTCTCTTTTTAACCACTGAAGCTATTTTCTTGCATTTTAGTTACTTACATTTGGGATGTATTTGCTTTTCTTTTAGCCTTGTAAACACTCTTTATGTATGCTGGAAGGAGCAGCTGTCCTTCTCTCCCAGTGCATTTCTCTCTTGCTACACAGTCATATTTGTTTTTTAGTGGACTCCACACTACTACACTTAGACATTTAGACCACTCCACTTACAAATTTAGAGCTGAAAACCCCTGGGCACAAGGTGGTTCACTGACTGTATGATCTTCACAGAGTACTTGCAGTTAGTGGTTGGCTGCTAAGTGAGTAAAACAAGCAACACCCTGGGCTATCAGGATACCTTGTTTATCCCGAGTTTCTTAAGTTGTACCTGATGCTTAGTATTTTTTTTTTTATCTAACTCTTACAAAACACTCCTCCAATTAAACTCATATTAAAAAAAATTTTTTTAATCTGTTCTTATTTAGAAATCTATGGTTTGTAGCCAAGTGTAGTGGAACACACATTTAATCCCAGCACTTGGTAGACAGAGGCTGGCAGATCTCTGGGTTTGAGGCCAGCCTGGTCAACATAGCGAGTTCCAGGACAGCAGAGCTATATGGAGAAACCCTGTCTCAAAAAGCAAACAAAAGAAAAATCTATGGCTTAGTACAGACCCCATCCATTAGAGTAATACCACACAGCCTAAGGACACCACAGCTTCTAGGTGATTTCATTCCTTACCTCTAAAAAGGCTTCTTGACACCTCTGAGCTTTTAATCCATGCCTTTGCTGTCTGCTCTACCTGAAGCATCTTTTTATTTTCTTAATAAACTATACACATCCTTCATGTCCCAGCTCCAATATGTTATCTTCTCTGAAGTCCTATCTGATAGCCTGGGCAGATTAGTCATTATCTTCAGTATTTCTCTAGCAACAGGTAACCTTTAAAAACAAAAACAAAAACGTAACTTTTCCCTCAGAGTTTTTGAAGACCAGCATCTTCATCTTTAGGTCCCCAATATCCTTTGAGTTTGATAGACATTTAAAAACAGATATTGAATATTCACTGCATGTTTTGAACTAGTTGCTAGGTGTATGATGTGAAGAAATTTAGACACCACTGAATGGATGACTAAGTCTGACTTCTAAGATCCTTGTTTTCTCTGCCCTGGCCCTTTAGGAGCCTGAGTGTGCTTTACTATCACTGCAGATCTTAAAAGGGGTGTCTGGGCTGCTGTTTTCCTATAAACTACCTAAGGTGTATGTGTGGTATCAAGCAGGCAAAAGGGGATGCCATCATTTCCATCTCACTGAAGCTAGCACAAATAGGAAAAAGTGAATTCTTTGAGTTATCCTCAAAGCTTTTTCAACCTTAGGATAAACTATGGTAATAATAGTTTTGAAAAAGATTTTCTTTGTATCATAAAATTGCTAGTTTAGTAGTTCAGCTCTTAATGTGCCCTGGTTAGGAAGTTATGTATTTGTACAGCTAAGAGAATAAATGTTACTGTTTTTACAAAGATGCAGTGACAGTGAAGCGTGTTTTTAACTTTATGTTGTATGCACTAG
Seq C2 exon
TGTTCAGTGTGGACTACAGTGATGAACTGGATATTTTGGTGAGTGGCTCTGCGGACTTCGCTGTGAAAGTATGGGCTTTATCTGCTGGGACATGCCTGAATACACTCACTGGGCATACTGAATGGGTCACCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000035949:ENSMUST00000028220:3
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0040027=WD40=PD(28.6=15.2),PF0040027=WD40=WD(100=53.0),PF0040027=WD40=PU(33.3=19.7)
A:
NA
C2:
PF0040027=WD40=PD(64.1=55.6)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTCAGATGACTTGTCTGCAA
R:
GGTGACCCATTCAGTATGCCC
Band lengths:
326-2024
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types