HsaINT0065770 @ hg19
Intron Retention
Gene
ENSG00000136877 | FPGS
Description
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:3824]
Coordinates
chr9:130569252-130569565:+
Coord C1 exon
chr9:130569252-130569366
Coord A exon
chr9:130569367-130569487
Coord C2 exon
chr9:130569488-130569565
Length
121 bp
Sequences
Splice sites
5' ss Seq
AAGGTGCCG
5' ss Score
5.74
3' ss Seq
GACATGTCCCTGTGCCACAGGAT
3' ss Score
8.05
Exon sequences
Seq C1 exon
CTCTCCCCACCTGGTGCAGGTTCGGGAGCGGATCCGCATCAATGGGCAGCCCATCAGTCCTGAGCTCTTCACCAAGTACTTCTGGCGCCTCTACCACCGGCTGGAGGAGACCAAG
Seq A exon
GTGCCGCATGCAGGAGGGCTGGCGGGTGGGTATGGTTGGGGGTGCTACGTGTTCCAGCACCCCATCTCCCCAGAGAAGGGGCTGCATGGGCTCTGGGCCCTGACATGTCCCTGTGCCACAG
Seq C2 exon
GATGGCAGCTGTGTCTCCATGCCCCCCTACTTCCGCTTCCTGACACTCATGGCCTTCCACGTCTTCCTCCAAGAGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136877-FPGS:NM_001018078:5
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF082457=Mur_ligase_M=FE(21.2=100)
A:
NA
C2:
PF082457=Mur_ligase_M=FE(14.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTCCCCACCTGGTGCAG
R:
CTTGGAGGAAGACGTGGAAGG
Band lengths:
188-309
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)