HsaINT0067245 @ hg19
Intron Retention
Gene
ENSG00000136750 | GAD2
Description
glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) [Source:HGNC Symbol;Acc:4093]
Coordinates
chr10:26581831-26589924:+
Coord C1 exon
chr10:26581831-26581920
Coord A exon
chr10:26581921-26589716
Coord C2 exon
chr10:26589717-26589924
Length
7796 bp
Sequences
Splice sites
5' ss Seq
AAGGTCAGT
5' ss Score
8.68
3' ss Seq
TGATATGGTCTGTCCCACAGGTG
3' ss Score
11.19
Exon sequences
Seq C1 exon
CCTCAGCACACAAATGTCTGCTTCTGGTACATTCCTCCAAGCTTGCGTACTCTGGAAGACAATGAAGAGAGAATGAGTCGCCTCTCGAAG
Seq A exon
GTCAGTGCTCCAAGCTCCTCTGATACATGTGTGTATTGAGCCTTTCATGTGCACATCTTCTTTATGACATATGCCTGTGGCCTTAGGAGACAGCCTACCTGGGTACATGGGCCCATTCCCGTCTGTGGACTCCTACAGAGCCAGGACATATAGAGCCTGATATATGCAGACATTTTTCTTCTTTTTTTTTTTTTTTTTTTTTTTGAGATGGAGTCTCACTGTGTCTTCCAGGTTGCAGTGCAGTGGCGTGATCTCAGCTCACTGCATCCTCCACCTCCCGGGTTCAAGCGATTCTCCTGCCTCAGCCTCCCGAGTAGCTGGGAATACAGGCACTCACCACCACGCCCAGACAATTTTTGTATTTTTAGTAGAGATGGGGTTTCAATATGTTGGCCAGGCTGGTCTCGAACTCCTGACCTCAGGTGATCTGCCCACCTTGGCCTCCCAAAGTGCTGAGATTACAGGCATGAGCCACTGTGCCCGGCCTATGCAGACTTTTAACAACTCTATTTGCTTGTTTTCTGAGAGTGAGTTTATGATGTCTTGAAAGAAGTAGTCAGGCGATAACCTTTGCTGGCATTCACAAAGCAACAAGGACGTTGCTGAAGTTCATTGATGTTCCAAGTGAAACTGGTGCTCAGTTACAAGCACAAAAGAGACTTTAGGTACCAGAAATGGTTAGCAAACAACGCTGCTGCTGACCCTCTTGAGCTGCCAAGGTCAAGGCTACCCTGGGTGTGTCCTTAGAGCTGTGGTGACCCCTAGAAGGTAAGAGGGCAAAGAGCAATAATAACAGCCACTGTTTTGAGTGTGCATTGTGTCCCAGCTCAATATCAGGTGTTAGGTCACTTAAAGCCTCAGAGCAACCTGACATGGGAAGGATTGTCCACCCATCTTGCTGATGGAGAAACTGACCCACAGGGAGAAAATGTAACTCCCAAAATCTCGCAGAAAGTCTGCATCCGAGCCTAAGGGCTTGAGCTTTAAATGGTACTGTGGTAAGACACCATTAATCTTTCATCCTCTCCTGCTCCCAGCACTTATACATGGGTGAAATGGGGTTTACAGTGCACATCGAAGCGGGGTATATGCAGGACCTGTCCCCCATTCGAAACTAGGGATGGTCATGTAGACTTGGATCTCAGAGTTGATTTGGTTGGTTTGGGGGTTCTTTTCATTTATCATAAAAGAGGGAACCTCCTCCAGTCACTGCCAAGAGCCCCGCAGGCTGTCCCCTCACTGCTCAGGAGCTTGGGCTGTCTCACTGACCTTTGGGAACACTTTAGTTCCTTCTACGTAAAATGAAGAAGAGGATTTTGTGTAGATATAAAACCTTCACTAAAGCTTTTATGTGTTAACATCTGTCCTTAAGCAACCCAAGATCAAACTCCTCATCGGGAGGAAACTTCCATATGGCTGAGGTCTTTAAACCAAGCCTCCTAATTAGAGTAGTGATTTGCAATCCTGGCCATACATTAGAATCATCCAGAAACTTCATAAAAGACACTAGTGACCAGGTCTCACCCTGAAAATGTAATCAGATTGTGCTTGGATGGGCCTGGGAATGATTCTGGAAGTTATCTAGATGATTCCAATGTGCACCTCAGCTAGAGAACCCCTGATCTAGAGGAAAAAATGGAAGAAAGCTTCTAGAACCAGGATCCGTGGTGCATGTGTCTGAGATGGAAGGGGCTGTGGTTGTGTTTGATGATTTCGTGAAGTTGGTTCATTCCAGGAAATCAAGCCCACAGGGTGGGAGGGAATGAGTAGAGGTCGCATTGGATAAGATGATCGGTGCAGGCAATAACAACGAGAATAGGGGGTGCGGGTGTCTGCTGTCATTTGAGAGGAAAAAATTCTTATTTTTCCTGGAATTTTTATGGTATACCTTCATAATGTAAAATTTCTTAACAATGACTTATTTAACCAGTTAGAAATTAGATGCCTCCATTCTTTTTGGCTTTCACTTCCTTATTGAACTGACTGGCCAGAAAGAGAATCCATGGACTAGTTTGGCTGATTTCATTTGTTGAATCAGTCCATTATCACTGGGCTGAGGGATGGAGCAAGATGGGAATACAGAATAAAAACTTTTTTTTTTCATCATTTTCTGAACAAAAGTCAACTTGGAGGCTCCCCCTTTTAAATATCACTCTTCAAATGCCTCCTAGGTTTCAGCACCTCATATGAGCTGTAATGAAGAATGGGGATGGAGATTATTTCCTGGAGATGGCAATTAGAATATTAGTAAACTGTTTTTATACTGTTGACAATTCAAATATGAAAATCTCCGGGGATTGCAGAATGAATTCTCCTGATTTTTCTCCAATTTTATTACTGTAATCAAGAGAATTCAGCAATTCAGATTTGGAAATGAAAATAGAACCACATGAATACCAAGTTTAACTTTTGTTCACGTATGCCAATGATTTTTTCAGACTTTCTGGAAAGTTCTTTATTAAGTGTGACGCCCTTAAAGTATCATGTCCAGGAACCAGTAAAATATTCATACGCATGCACACACACACACACACACACACACACACACACACACACAGTCCCAGAGGGAAAAGAACTGAGGTGAAATAATCTATGCTGTCCAGTATGGTAGTAATAGCCACATGTGGCTATTCATATTTAAATTTAAATCAATTAAAATTAAATTCAACCAAAAATTTGGTTCTTCAATCACACTAGCCACATTTCAGTCACTCAACTTGTGCCCAATGGCTGTTTTATGGGACAGTGCAGATATAGAACATCTCCATCACTGCACAGAGTTCTGTTGGTCCAGGCCGATATAGACTCAAAATTTGGGGAAATGCAGAGTTTCCTGTGCAGTTTATGTGAACCAAAAGAACAAAGTTAAATTCTGGACAAGACAAGGCAGAGAAATTACTCTGTACCATCTTGCCTGATTCATAGCTGTAGTGCACAATAGGAACTCAAAAATCGTTTGTTGAGCTAAAATTGTATCTTAGCGTGGTTGAGCTGCAAAAACAGACTAATATAGACTGGGTAGCTTATAAGCACAGAAATTTATTTCTCACTGTTCTAGAGGCGGGGAAGTCCAAGATCAAGGTGCCAGTAGATTCCGTGTCTGCTGGAACCCCTACTTCCTGGTTCGTCAATGGCCTTTTTCTCCCTGTATCCTCACATGGCAGAAAGAGGTCAAGGGAGCTCTCTGGGGTCCCTAAGACTGTGCCTTCCTGAACTAATCACCTACCAAAGGCCCTATCTCCTAATATCATCACATTGAGGGGTTAAGATTTCAACATATAAATTTTGGGAGGACAGAAAAATTCAGTCTATAGCAAATACCTTAGGCATATTCCAGAATAAGGAAGGGAAACAACATTTAGGAAACCTAATAGTGGCTCATAAGCCTTTTTCCAGAGTGCACTATTTGGGGACAAATATCTGGATAACAGAAGTTATTAATAAAGCAAATACAGTCATATCTTCATGAGGGTGGTAAACACGAGAATCCAGTCAGTGTGCTTCCTGCTGCTCTGTCAGGACTATGATCTTGCAGATGGCGCTTTGTCCCTGAGGCAGTGCAGATGATGAATGCTTGGGGCACTATGAGGATGTGACGCCACACACATGCCTTGGACACAGGGAGGGGCAGCAAGTGGGCTGTGCCAATGTTTACCAAACAAGAATCAAAAGGGCTGGTCTATTGATCACCTCTTGTGTTTCTGGTTCTTTATCTTCTTATTTTAATTTTTTTTATTCTTGATCATTATCTGGTTCTGTCAGCTTTTATAGTCCTACACTGATTGGAGGACTTTTCAAAGGTTAGCAGTGGATTTAATACTAAATTTGTAAGGAAGTAGCCTGGACTTATATTTAATACAGACTCTTTGAAAGTCTGTGTTATTAAGTGCAATAGAGGATTTAATTGGTGAAATTTTCGCATATTAGAATTTTTTTTTTTTAAGACAGGGTCTCACTCTGTTGCCCAGGCTGGAGTACAGTGGTGCCATCTCGGCTCACTGCAACCTCCACCTCTCAGGTTCAAGTGATTCTCCCACCTCAGCCTGCCGAGTAGCTGGGATTACAGGCACACACCACCACACCCAGCTAATTTTTATATTTTTTGGTCAGGACAGGGTTGGGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTCGAACGCCTGACCTTAAGTGATCGGCTCACCTCGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCAAGCCTAGCCAACAGTTTAGAATTTCTCATTTAATTATTCTGCTTTTACATTTTTCAGAAATTTCTCGCAGTCTTCCAAAATGTAAAAACAAAGAGGTTTTCTAAGACATAGTGAAAAATACATTTCTGTGATATCTTTTAAGTTTATTTCATAATGCTTTACTATGCACCCTCTTTGAAAGGGACAAATGTGGATTCCAATTATGGAAAAGTCGCCTGGTTATTGCTTTCTAAAGGACTGAAAAAGCTAATGGCACAAGAGAGAAGACAATACCCTAAAATTATTAAGGCAGGCCCAAAGAGCTCTTGTTGACTATACCTTTAGCGAATTCTTCAACATGCAACCACTCTTTCTCAACTTGCGTTCTTTATTTAGGAAAACTAGGAATCCAACCAAAAAGTACAAAAGCCTAGAAATAAGTGAAATCTCTATGTATTTCATCCAAAAGACCACTGGGATGGCTAGATAGTAGAAAGGAGAGCTTTATTGATGATATCAGTTTGCAAACTGGGAAGAGACAGCCTCCAGCATGTGTGGAAGGTGCCCTCTCTTCCAAGAGAGGAAGGGCAGGTTGGGTTTTATGCCTCACAGGGCCTGTATCACACAGTAGAGTCATACATATTCAGTAGGTTTTGGGGGAAAGCTATCCATATTTATGAGGGGAGCTGAGCACATGCAGAATGAGTAAACATATATGTAACATACATCCCATGTTTACTTCGGGGCAGGGTTTTAGTGTTAGAATGAGGTGAAATTTGGCTCTTCATGTCAAAAGGTGAACTGTAGGACATAAACACAGTTTGTGCACCGCATCTATAAGCTGCTAAAACTGGCTTAAGGTCTGCAATTGCTTACCAGGAAAGAATGTGTGTAAGGTCAGTCTTCTGTCTAGTCAGAGTTATAGTGGTCTGGTTAGTAAATCAGGGTAAGGAGGGGGTCTCATAGCGCCTATTGTTAGGGAATTTCAATCATTAGGAATTTAGTAATTTGCCCTCCAGCCAGGCCTTGAACCCTGGACCCATCTTAGTTGATATAGGAGTGTCTATTTTGGCCCCACAGATCACATATATTCATCAGAATAGTCCGAATCTTATTTTCCTTCTTAACTTGCAATGAGTGAATATACAACGAAGTAGATGTTCATGTTCCGGCTAATTTTAGTTCATCAGCATTTTCTGGAAGCAACCAAAAGTCATATGTATTTAGACAGCTGTGATTTCTGCCAATTCAGCTTGCTTCGGGAACTGAGGGGATTCAATCTTACTTTATGCCCAAATCTGTTTGCTTGTGGCTGTTAGCATTAATCTTTTAACCTTTGATTTGCATTCATCTGAAAAGCTAGAGATGATTGTCCTTAATAATTAGTGCCATTCTTCTGTATTTTTGCTTGGATTACCCATGAAAACTAAATGAGACTTTAATTTACTGAGTAAAGCTCTGTCATTATTTTATCAGTTCTAAAGGGCAAGCGTGATTTATTATACAAATAAAACTAAGGAATGGTTATGTGACTTGTCCTTAAATTCCTGCAGCCAAGTGGATTTGGAATTCCTTTTCTAATCTGAGATTTATCTTCGCAGGAACCACATTGACTTGACACGCCTCACAACACAAAGGATAAATTCCATGCCCCTTTGGCTGGAATATGCTAGTAGATCTATTTTCAGAAGTTAATCTCAGATTTGAGATATTTTAATTCTTCTTCTTATTTATTCCCTGGGATGAGTCCAGTGCTCTGCATACATTCTTAATGCTTTAGGTGAAAGAAGGATCAGGCCAAGAGAAACATTCCTCCCCATGGAACAAGGGGTGGGAAGGGATATAAGAACTCAATGTAGAGTCAGAAGATCTCAATGCTGGAATCATCCACGTTCATTTTTAGAGAAGGAAATTAGGTTCAGAATGAGAAGTGAAGGTGAAGTCTACCTGTTGACCTTGTCTTTGGTAACTAACAAATGATTGGACCCAATGGGAACATTGCTATTTTATGCATTGGATACTTTGAAGATGAAAACTTCATTATAAACCAATGATTATTTAAGAGTTGATATTTATAAGTCACATGTTCATAACAGCATTCCATTTGAATTGAACTGTCTATTTAAGATAAATCCAGCTGTGATAGAAGGCATGGTCTCCATTTTGAACCGGGTTTCTGACCATATGAAACTCAAAGAAGTCTAAAAGTTTCTCTGATGTCTATCTACCATTTGCAGAAATGAAGATCAGATATTATATATTTACAAACTCCAGTGGTAAATATATGTGGATAGACTGTATGTACAGTTAGACATGATTTAAGTTTTTGCTTCTTCCTAGATAGCTGTTTCTATTATGCTACTCTTTATAGCAATAAGAACTTAGGAATCCCCCAACATGAACCAAGCACTGTGCTGGTAAAGAACAACAACAAAAACAGTAGAAGACACTGTGTCTGCCCTCCAGGACCTGACAGTTGAGGTAGAGAAAGAAAATGTATTTGCTTGAAAGTAAGAGGATAGTAGGAAATTAGCATATAGTCAGAATCTATGGGGAAGGATCATGGATGATATGTTTACAGCTTAAAGGAAGAGAGCTACTGATGGACACTAGAAGTCAGGAAAGGCTTCATAGCAGTTGTAGGACTGTGGTGGAATCTTGAAGTGTGTGTAGGATATGAACCAGAAGAGAAAAGGGATGGATTCTAAGCACAGAGAACAAGTATGACATAGTAACACTGATGACAAGTGTGAAGGGATAAAAATACATATGGTAAATTCAAGAGATATTTAATAAAGGAGTCTTGTCAGAGTTGAAGATTCATTTTGGCAAGTGGTGGAAGATGAGGCCTCATAAATGGATGATGAAAGGTCTTTGCACTGAACTAGAGTTTAAACTTAATTTCATATACAATAGAGAGCTACTGAGGCTATAATCAAAAATCTGGCATAAATAGAGTATAATCTCGTCTGTGGTATGCTATCCTGTCTGTGATATGAAACATATGTTAAGTCCTTGTGAGTTCAGCTTTTTGTCCCAGCTAATTATCATCATTATTAAGGATTATCTTTCAAAATATCTTATAAAGTGAGGCACTGCAAAGAGAGAACGAAAAGAAACTAGAAAGCTCTGGGGTTTCAAGAAAGTTGCCAAAAGTCTGCTTATCTTCATATATCACCTGACACTCAAACTTACATTTTGGTAACAATCCTCTGAACTGTTTATTTCCAATGTTTTTACATTTACTGTGGGGGGAAAATGCCCCCAAACGTCTTGCTAACCCATTTAGCTTGGGGCCAATACTAGATTCATCCCATCCTCCCAAAACACTAACTGGAAAGTCAAGGACAAGGTGGCAGGCAGCTGATAGTCTATCACTTATTATTCCTCTTATCACTTGCAGGATCTTGAATGTGTTAGACTGTTCTAATTCTCTGATCCCAAGAAAACTTGGAGGTAACTCTTTCAAGAGAAAACAATAAGGTTCTGACTGTTGAGCTAAAAACTAAAGACGCTGCTTGCTGTTGGGTTCTTTGACTCAGGGGAGAGTCCCAGGAGAAAGTCACCATGCTGATATGGTCTGTCCCACAG
Seq C2 exon
GTGGCTCCAGTGATTAAAGCCAGAATGATGGAGTATGGAACCACAATGGTCAGCTACCAACCCTTGGGAGACAAGGTCAATTTCTTCCGCATGGTCATCTCAAACCCAGCGGCAACTCACCAAGACATTGACTTCCTGATTGAAGAAATAGAACGCCTTGGACAAGATTTATAATAACCTTGCTCACCAAGCTGTTCCACTTCTCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136750-GAD2:NM_000818:15
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0028214=Pyridoxal_deC=PD(2.7=33.3)
A:
NA
C2:
NO
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)