HsaINT0068285 @ hg38
Intron Retention
Gene
ENSG00000106633 | GCK
Description
glucokinase [Source:HGNC Symbol;Acc:HGNC:4195]
Coordinates
chr7:44146463-44147833:-
Coord C1 exon
chr7:44147650-44147833
Coord A exon
chr7:44146619-44147649
Coord C2 exon
chr7:44146463-44146618
Length
1031 bp
Sequences
Splice sites
5' ss Seq
GCTGTAAGG
5' ss Score
4.86
3' ss Seq
TGGACCTGCCCTATGTCCAGGTA
3' ss Score
6.07
Exon sequences
Seq C1 exon
GCACGGGCTGCAATGCCTGCTACATGGAGGAGATGCAGAATGTGGAGCTGGTGGAGGGGGACGAGGGCCGCATGTGCGTCAATACCGAGTGGGGCGCCTTCGGGGACTCCGGCGAGCTGGACGAGTTCCTGCTGGAGTATGACCGCCTGGTGGACGAGAGCTCTGCAAACCCCGGTCAGCAGCT
Seq A exon
GTAAGGATGCCCCCCTCCCCCACAACCCAGGCCCTGGGCCGCTCTGGTGCAGCGGCAGATGGGAGCCGGGCCATTGCAGATAATGGGCTTGTTTTTAAACAACTCTGGGGAAAAGCAAACTGACAATCCGTTCGTAAGCTCCATCCCTTCTGCTCAGTCATGACCTGCCCCTGTGAGAGATGAAGGGTTAGTCCCAGTTGTGATGTGATAAGCCCAGACCTCTTTCCTTCCGACAGGTGATCGTGCATGCAGAGGAGGCTCTGAGACGCCCCCAGCAAGGTTCCTGGGTTTAACCCAACATTCCCCAAAGTATGTATTTGGCCACATTCACAGAAAGAATATTAGTCTTTTGTGGAATGCTGCGGGTTGACAGTCACAGCTTGGAAACCAACCCACAGAGAGCTCATCATTAATCATGGCTATCACTTGTTTACCACCTACTGTGCCAGGCCTATGCTAATTACTTTATTAGCGTCCTCTCTGCCGCTCGCAGGCCTCTATTATTATAGGTCAGTAGTATTCGATTTATTTAAATTAAATACGGAAGGTCATAGATTAAGCAAGAAAGTGCCAGCAACATGGTGCGTGCCTCTGACTGGGCACTAACCCTCCAAGTCTTAGTTTTCCCAACCATAACTGGCCAATGAACAGCAGCTCTGGATGCAGCTAAAGGAAGACTGAAGCTGTAGGTCCCGTGCTCGGCGCAGGGCCCCCTGCAAGGAAGGTTTCGGAGGGACTGGATGGGGTCTTTGAACTATCTGTCTTTCCCTTTACTGCAGTGGGCCCAGGGGCAGGCCAAAGTTGCTCCCGTGATTGACTTGAACGTGCACGTTCCTAATCCCTGACATTTCTAAAGCTCTGGCTCATTAACGAGGGAAAGACGTGAACCAGCTGGGGGAGTGGGGATCGCAGTGCCCCACGTGGCCGCCTCGTGACCTCAGTGGGGAGCAGTGGGGCCGGCTCCCGGCTTCCACCTGCATGAGGGGCCCTCCCTCGTGCCTGCTGATGTAATGGACCTGCCCTATGTCCAG
Seq C2 exon
GTATGAGAAGCTCATAGGTGGCAAGTACATGGGCGAGCTGGTGCGGCTTGTGCTGCTCAGGCTCGTGGACGAAAACCTGCTCTTCCACGGGGAGGCCTCCGAGCAGCTGCGCACACGCGGAGCCTTCGAGACGCGCTTCGTGTCGCAGGTGGAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000106633:ENST00000403799:7
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.016 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0372711=Hexokinase_2=FE(25.4=100)
A:
NA
C2:
PF0372711=Hexokinase_2=FE(21.7=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCTACATGGAGGAGATGCAGA
R:
CTCTCCACCTGCGACACGAAG
Band lengths:
323-1354
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development