HsaINT0073787 @ hg19
Intron Retention
Gene
ENSG00000169919 | GUSB
Description
glucuronidase, beta [Source:HGNC Symbol;Acc:4696]
Coordinates
chr7:65425673-65429445:-
Coord C1 exon
chr7:65429310-65429445
Coord A exon
chr7:65426051-65429309
Coord C2 exon
chr7:65425673-65426050
Length
3259 bp
Sequences
Splice sites
5' ss Seq
AGTGTAAGT
5' ss Score
8.46
3' ss Seq
TCTTTTTTTTTTTTTTGTAGCAC
3' ss Score
10
Exon sequences
Seq C1 exon
GATCCACCTCTGATGTTCACTGAAGAGTACCAGAAAAGTCTGCTAGAGCAGTACCATCTGGGTCTGGATCAAAAACGCAGAAAATACGTGGTTGGAGAGCTCATTTGGAATTTTGCCGATTTCATGACTGAACAGT
Seq A exon
GTAAGTGGCAGTTTGGCTCATGGGATAACGTACCCGTCCTCATTTTTTCAGGTTGCCTTTCCAATTCTGGCCATTTCAATTGTAAGAATATTGGAAACAAAGTTGGGGAAGCTGGTTTAATCCATGTAGGTTGCGTTGAGAATTTTCTAGGAAAAGTAAGTTGTGTTTAGGAAGTAGGAAAGCAATCAGGCCCCCGCCTCCCAAATACGGTCAAAAAGCAAACAGGAGAGTCAGCTATAGTGAATCGGAAATGGCTGGCTTGCCTTTTCCTTGTCTATTTTGTAGCCAAGGAGGAACGAAAAACGGGACCTCATCATGGATTTACTTTTGGGATACACTCATTATTCCATAGAAGGGTACAAAGCCTGAGAAACTTAAGGTATTTCAGTCTGTTGTATATTACTTGCGAAAAGCAGGCTTATCAAATACAGGTGAGTTTCAACGCATCTTGAATTTGGCAGCATTTACAAGTCTTCAGGCCAGGTGTAGTGGCTCACGCCTGTAATCCCAGCACTTTGGGAGGTCAGGGTGGGAGGATCGCTTGAGGCCAGGAGTTCAAGACCAGCCTGTTCAGCATAGCAAGACCCCATCTCTACAAAAAATAAACAGATTAGCTAGGCGTGGTGGTGTGTGCCTGTAGTCTCAGCTGCTTGGGAGGCTGAGGCAGGCGGATAACCTGAGCACAGGAGTTGGAGGCTGCAGTGAACTATGATTGCACCACTGCACAAGAGCCTGGACAACAGAGTGAGACTTGTCTTTAAAACACAAGATTGGTCTTCAAAGAGAATAACATCTGCGGTGTCTTGTGAGGATGGATGAGGGGCTGCCAAGTTCGCAATGAATGTGTCCCATTTCTTCTTAGTTTATGGACTTACCATAAACTGAAGATAGCAGTTTGGTGGGTTGGAGAAGCATGTGGTAATGGTGGGAATTATAATACATTACTTACAGGGAAAGACAGGCCTTTGAAAGGTAAAGCGTAAGAGTGAGAATGGAATACGGATGAATGAATGAACAAGATGAGGTGAGAAGGAAGAGGTAAAGGGAAAAGGAGAACAGGAAGCTGTCCTCTGCGTGGCACCTGTGATAAATGGTTTCTGGGGACATCCCTGATGGCAGTTTTGTGGAGAGGTGCGAGGCTTTATGCGGTAAGAAATGAGCTGCAGGCTGGGCGCAGTGGCTCAAGCCTGTGATCCCAGCACTTTGGGAGGCCAAGGTGGACAGATCACCTGAGGTCAGGAGTTTGAGACCAGCATGGCCAACATGGAGAAACCCCATCTCTACTAAAAATACAAAATTAGCCGGGTGTGGTAGCGCATGCCTGTAATGCCAGCCACTTGGGAGACTGAGGCATGAGAATCTGTTGAACCTGGGAGATGGAGGTTGCAATGAGCTAAGATCACAGCACTGTACTCCAGCTTGAGCAATAGAGTGAGACTCTTTTTTTTTTTTGAGACGGAGTTTTGCTCGTTTCCCAGGCTGGAGTGCAGTGGCGCTATCTCAGCCTACTGCAACCTCCACCTCCCAGGTTCAAGCAATTCTCCTGCCTCAGCCTCCCGATTAACTGGGATTGCAGGCATGCGCCACCACACCCGGCTAATTTTGTATTTTTAGTAGAGACGGGGTTTCTCCATGTTGGTCAGGCTGGGCTTGAACTACCGACCTCAGGTGATCCGCACATCTGGGCCTCCCAAAGTGCTGGGATTACAGGCATGAGCCACCATGGCCAGCTGAAACTCGGTCTTAAAAAGAAAAAAGAAATGAGCTGCATCACGTTGGGCAAGTCACCTAAGCTTTTCATAAGCCTGTCCAGTGGGGATAATGCCACCTCCTTGTTGGTGTCGTAAGGGCTGCATTTGATGAAGTACTTGGCGATGCCTGTGTTCACTTATGGAAGAAACAGTCTTGAACCTTTTGGTGGGGAAAGCCCCCTTTCCATTTAACATTTCCATTTAGTGGTGGTCTTACTGGGGACAGAGAATGTCCTGAGAGCACAGCCCTGACAGGTCGTTGCCAGCTGTGCTCCTCCACCAGGCTCAGCTCAGGCCTAATGACCACCAGTGGTGGGTGCTGCCAAGCTGGACGTCAGCCCCGGCGGACTTTGAACTCCATGAGTAGGTCCCACGCAGGGACCTGTGGCTGGTCAGGACCCTGGCTCCCACTAGGCGCTATCTCTTCAGAAAGGCCCAAGGCTTTTCAAGGGTAACTGTCCCAGATACCCCTAGCCCTCTGCCTACCCAGTTACCAGACAGCTGGGTACCCAGCATGTAAACCTTAGTTTGCAAATAAAAGATAAACTTTTAGTGCTTTTTTTTTTTTTGGAGATGGAGTCTCACTCTGTCGCCCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCTGCGTCCTGGGTTCAAGCGATTCTCCTGCCCCAGCCTCCTGAGTAGCTGGGACCACAGGCACCCACCACCATGCCTGTATAATTTTTGTATTTTTAGTAGAGATGAGGTTTCACCATATTGTCCAGGCTGGTCTTAATCTCCTGACCTTGTGATCCGCCTGCTTTGTCCTCCCAGAGTGCTGGGATTACAGGCATGAGCCAATGTGCCCAGCCAGTTTTTGTATTTTTAATAGAGGCGGGTTTCCTCATGTTGGCCAGGCTGATCTTGAACTCCTGACCTCAGGTGATCCACCTGCCTCAGCCTCCCAAAGCACTGGGATTACAGGCGTTGGCCACCACACCTGGCCACTGTTTTGGGTTTTTTTCCCCTAACAGACTAGAAAACTAGAAATTAACACACCAGGGAACCTGGGTGTTTGGGCAGAGCAGTGGTATTTAAATATTTCAACCCATAAATTGTCACTTCAGAGCAAGCATCCTGAAACTGTAAGAGGACATTTGGCTGAGCATGGTGGCTTGTGCTTATAATCCCAGCACTTTAGGGAGGCTAAGGAGGGCAGATTGCTTGAGCCCAGTAGTTTGAGACCAGCCTGGACAACATAATGAGACCTTGTCTTTACTAAAAAATAAAAATAAAAGATTACCGGGCATGGTGGTGCTGGAGAGGCTGAGGCAGGAGGATTGCCTGAGCCCAGGAGGTTGAGGCTGCAGTGAGCTATGATTGTGTCACCGCATTCCAGCCTGGGCAACAGGGAGAAAAAAGAAAAAAAAAGACATTTCTATTTAGTGCCTACCTTAGCTCCAGACTGGTTCTAACTTGACCCATCAGAAGACATCTGAATCGCTTTGTGTCTTTTTTTTTTTTTTGTAG
Seq C2 exon
CACCGACGAGAGTGCTGGGGAATAAAAAGGGGATCTTCACTCGGCAGAGACAACCAAAAAGTGCAGCGTTCCTTTTGCGAGAGAGATACTGGAAGATTGCCAATGAAACCAGGTATCCCCACTCAGTAGCCAAGTCACAATGTTTGGAAAACAGCCTGTTTACTTGAGCAAGACTGATACCACCTGCGTGTCCCTTCCTCCCCGAGTCAGGGCGACTTCCACAGCAGCAGAACAAGTGCCTCCTGGACTGTTCACGGCAGACCAGAACGTTTCTGGCCTGGGTTTTGTGGTCATCTATTCTAGCAGGGAACACTAAAGGTGGAAATAAAAGATTTTCTATTATGGAAATAAAGAGTTGGCATGAAAGTGGCTACTGAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169919-GUSB:NM_000181:11
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
Alternative protein isoforms
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0283612=Glyco_hydro_2_C=FE(14.9=100)
A:
NA
C2:
PF0283612=Glyco_hydro_2_C=PD(11.2=60.7)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)