HsaINT0073932 @ hg19
Intron Retention
Gene
ENSG00000100450 | GZMH
Description
granzyme H (cathepsin G-like 2, protein h-CCPX) [Source:HGNC Symbol;Acc:4710]
Coordinates
chr14:25076355-25076953:-
Coord C1 exon
chr14:25076818-25076953
Coord A exon
chr14:25076613-25076817
Coord C2 exon
chr14:25076355-25076612
Length
205 bp
Sequences
Splice sites
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
3' ss Seq
TCTTGCTTCTTCCCCACCAGCTG
3' ss Score
8.51
Exon sequences
Seq C1 exon
CTCCATAAATGTCACCTTGGGGGCCCACAATATCAAGGAACAGGAGCGGACCCAGCAGTTTATCCCTGTGAAAAGACCCATCCCCCATCCAGCCTATAATCCTAAGAACTTCTCCAACGACATCATGCTACTGCAG
Seq A exon
GTGAGGCACACTCCTGCCACTCTTGCTCTTCTTGGTCCAGTTGGTTCCACTCCCACTGGGATGCCGGCCCTTTCCTCCTTTCCATCCTGACCTCTTGGTCAGTTCCTGTGCCTTAGAGGAGAGGGAAGATTGTGCAGCCCCATCACTGTGTCGGGGCCCAGAAGGCCATTGCCTGACCTGGACTTTCTTGCTTCTTCCCCACCAG
Seq C2 exon
CTGGAGAGAAAGGCCAAGTGGACCACAGCTGTGCGGCCTCTCAGGCTACCTAGCAGCAAGGCCCAGGTGAAGCCAGGGCAGCTGTGCAGTGTGGCTGGCTGGGGTTATGTCTCAATGAGCACTTTAGCAACCACACTGCAGGAAGTGTTGCTGACAGTGCAGAAGGACTGCCAGTGTGAACGTCTCTTCCATGGCAATTACAGCAGAGCCACTGAGATTTGTGTGGGGGATCCAAAGAAGACACAGACCGGTTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100450-GZMH:NM_033423:3
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
No protein impact description available
No structure available
Features
Disorder rate (Iupred):
C1=0.130 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0008921=Trypsin=FE(20.5=100)
A:
NA
C2:
PF0008921=Trypsin=FE(38.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGCGGACCCAGCAGTTTATC
R:
AGTGGCTCTGCTGTAATTGCC
Band lengths:
306-511
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)