HsaINT0075314 @ hg19
Intron Retention
Gene
ENSG00000198265 | HELZ
Description
helicase with zinc finger [Source:HGNC Symbol;Acc:16878]
Coordinates
chr17:65145983-65147340:-
Coord C1 exon
chr17:65147162-65147340
Coord A exon
chr17:65146102-65147161
Coord C2 exon
chr17:65145983-65146101
Length
1060 bp
Sequences
Splice sites
5' ss Seq
CTGGTATGC
5' ss Score
6.73
3' ss Seq
GTTTATGCTGCATTTTCTAGGGT
3' ss Score
8.33
Exon sequences
Seq C1 exon
GGTATATTTCAGAAATCGCTGGGTAAAGACTGTCCACCCAGTTGTGCATCAGTACTGTTTGATCTCAAGCGCACATTCCACCTTTCAGATGCCCCAGAAAGAAGATATTCTTAAACATCGAGTGGTGGTTGTTACCTTGAATACTTCCCAGTACCTCTGTCAGTTGGACCTTGAACCTG
Seq A exon
GTATGCTGACTCAAGACACAGTCTCACAAGTTTAGGGCTTATGAATTCAGTTTAGACTGGGATTGGCAAACTACAGTGTGTGGGCCAAATCTGGCTCACTGACTGTTTTTGTAAATAAAGTTTTACTGGCTCATTTATTTACCTATTTATTGTCTATAGATGCTTTTGTGTTACAGTGGCTGAGTTGAGTTGTTGCAGCAGAGATTCATTATATGGTCCACAAAATCTAAAATATATACTGTTTGGCTCTTTACTGAAGAAAAATTTGCCAGCCTCTAGTTCAGACATTTTAGTGACTGCTATTCCATTTATTCTCTAGTTGGTCAGATGATGTTTATTATTGATCATATGAAGAATTCCAATTTGGAGAGTGTTGGTGTTTTCCTTTTCTTTTACACTTTTCTCAGATTTTTGTTATAAAATGCTTTTGCATTATATACTGTAGAGATGATAATTATGATAGGTTTTATTATGGCATGTTATTAAGATTGTTATATTTGAGTACAGGAACCATGTAAAATCAAACTAGTGTTATGTGAAGTACAGATGTAAGATGTCAAGAAGTTGTTCTGATAAATATGGCAAAACTTAACCATCAAAAAGCAGTACAAATCTGGGGCCAGGCGTGGTGGCTTATGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCAGGCGGATCACTTGAGGCCAGGAGTTCAGCCAGACTGGGAAATACAGTGAAACCTTATCTCTACAAAAAAGTTCAAAAATTAGCCAGGCCTTATGGCATATGCCCGTAGTCTCAGCTACTTGGGAGGCTGAGGTTGGAGGATCACCTGAGCCCGAGGCTACAGTGAGCTGTGATCATATAGCACTGCACTCCAGCCTGGGAGACAGAGTGACACCCTGTCTCAAAAAAAAAAAAAAAAAAAAAAAGAAAGAAAATAAATAAATAAAAGTACTCAATACTCTTAGATTAGCAAACTAAACTCTTTACTTAGCAGAAAAGAAAATAACTATAGTCCTTCTGCCTTTGTTGCTGCTCTAGCGTGCTATCCTGTGTTTATGCTGCATTTTCTAG
Seq C2 exon
GGTTTTTTACACACATTCTATTAGATGAAGCTGCCCAGGCCATGGAGTGTGAAACCATTATGCCTCTAGCATTAGCAACTCAAAACACTCGGATTGTCTTGGCTGGTGATCACATGCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000198265-HELZ:NM_014877:18
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF130861=AAA_11=PD(28.3=55.7),PF130861=AAA_11=PU(42.9=59.0)
A:
NA
C2:
PF130861=AAA_11=FE(46.4=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTATATTTCAGAAATCGCTGGGT
R:
GCATGTGATCACCAGCCAAGA
Band lengths:
296-1356
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)